期刊
SPRINGERPLUS
卷 5, 期 -, 页码 -出版社
SPRINGER INTERNATIONAL PUBLISHING AG
DOI: 10.1186/s40064-016-3683-2
关键词
Tibia and fibula fracture; Non-union; Autologous platelet lysates; Percutaneous injections
资金
- Opening Project of Shanghai Key Laboratory of Orthopaedic Implant [KFKT2015003]
Background: Nonunions of the tibia represent challenging orthopedic problems, which require the surgeon to analyze numerous factors and choose an appropriate treatment. This article presents a case report of tibia and fibula fracture patient who failed the internal fixation surgery and successfully recovered after one course of percutaneous autologous platelet lysates injection. Case description: The patient received an internal nickelclad breakage at 9 months post-surgery but reluctant to accept a second surgery, then autologous platelet lysates (APL) injection which is a less invasive method was recommended. The injections were carried once a week for three times. Radiologic evaluation was conducted every month until recovery. Discussion and evaluation: To the best of our knowledge, this is the first reported case of tibia delayed union with breakage of the plate resolved with APL injection. Improved clinical evidence was observed at 4 and 6 months after injection. The patient got good bony union at 8 months post-injection. The patient didn't feel any discomfort post-injection, no complications such as infection, refracture etc. were observed. Conclusions: APL percutaneous injection could be a new therapeutic option for the treatment of nonunion or delayed healing fractures.
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