期刊
ORGANIC CHEMISTRY FRONTIERS
卷 3, 期 3, 页码 335-338出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5qo00372e
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资金
- Tsinghua University
- Thousand Plan Youth program of China
- Bayer
- Tsinghua-Peking Centre for Life Sciences (CLS)
The first NHC-catalyzed dehydrogenative coupling of enals is described. With a suitable combination of NHC precatalyst, base, and solvent, the reaction proceeded smoothly to yield a wide range of monobactams. These substituted monobactams have been synthesized for the first time, and they are versatile synthetic intermediates toward other useful complex molecules.
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