期刊
INFLAMMOPHARMACOLOGY
卷 24, 期 2-3, 页码 81-86出版社
SPRINGER BASEL AG
DOI: 10.1007/s10787-016-0264-5
关键词
Curcuminoids; Antioxidant activity; 2,4,6-trihydroxyphenolic chalcone; Ascorbic acid; Diphenylpicrylhydrazyl radical
资金
- Karadeniz Technical University (KTU-BAP) Trabzon, Turkey
The antioxidant properties of the synthetic compound (C1)-(C8), which comprised 7 curcuminoids and a chalcone, were evaluated by two complementary assays, DPPH and beta-carotene/linoleic acid. It was found that, in general, the free radical scavenging ability of (C1)-(C8) was concentration-dependent. Compounds (C1) and (C4), which contained (4-OH) phenolic groups, were found to be highly potent antioxidants with higher antioxidant values than BHT suggesting that synthetic curcuminoids are more potent antioxidants than standard antioxidants like BHT. Using beta-carotene-linoleic acid assay, only the water-soluble 2, 4,6-trihydroxyphenolic chalcone (C5) showed 85.2 % inhibition of the formation of conjugated dienes reflecting on its potent antioxidant activity.
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