Article
Biochemistry & Molecular Biology
Emad A. S. Al-Dujaili, Ciara Casey, Angela Stockton
Summary: This study investigated the effects of pomegranate extract on cardiovascular risk factors. The results showed that pomegranate extract intake improved antioxidant and oxidative stress status and attenuated some cardiovascular risk factors.
Article
Agriculture, Multidisciplinary
Kais H. Al-Gubory, Ismail Laher, Catherine Garrel
Summary: The study showed that pomegranate peel powder can protect the small intestine against DSS-induced lipid peroxidation by enhancing the GSH/GSSG redox potential. The powder contains bioactive polyphenols and has the potential to be used in functional foods for preventing oxidative stress-induced small intestine pathogenesis.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2021)
Article
Food Science & Technology
Angela Stockton, Emad A. S. Al-Dujaili
Summary: This study assessed the effects of oral pomegranate extract and pomegranate juice on satiety parameters in healthy volunteers. The findings suggest that consumption of pomegranate extract can reduce the desire to eat, increase feelings of fullness and satisfaction. These results indicate the potential of pomegranate extract in reducing appetite and aiding in weight loss.
Article
Biochemistry & Molecular Biology
Raul Arcusa, Juan Angel Carillo, Begona Cerda, Thierry Durand, Angel Gil-Izquierdo, Sonia Medina, Jean-Marie Galano, Maria Pilar Zafrilla, Javier Marhuenda
Summary: This study aimed to evaluate the efficacy of long-term consumption of high polyphenolic content from fruits and vegetables (such as berries) as a nutraceutical against central nervous system lipid peroxidation, as assessed through urine biomarkers. The results showed significant reductions in AdA and DHA-derived metabolites after consumption of the nutraceutical, indicating its effectiveness in preventing CNS lipid peroxidation.
Article
Biochemistry & Molecular Biology
Marina Reguero, Marta Gomez de Cedron, Aranzazu Sierra-Ramirez, Pablo Jose Fernandez-Marcos, Guillermo Reglero, Jose Carlos Quintela, Ana Ramirez de Molina
Summary: Obesity is associated with chronic inflammation and metabolic disorders. A Mediterranean diet and pomegranate extract (PomE) can reduce inflammation and improve metabolic symptoms.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Endocrinology & Metabolism
Laine de Carvalho Guerra Pessoa Mamede, Rafaela Lira Formiga de Cavalcanti de Lima, Alexandre Sergio Silva, Joao Carlos Lima Rodrigues Pita, Nadjeanny Ingrid Galdino Gomes, Elisama Araujo de Sena, Rhayra Priscila Moraes Nobrega, Joao Otavio Scarano Alcantara, Julie Hanna Fontes de Souza, Glebia Alexa Cardoso, Jose Luiz de Brito Alves, Maria da Conceicao Rodrigues Goncalves
Summary: The study found that VD3 supplementation increased 25-hydroxyvitamin D levels and reduced specific oxidative stress and inflammation markers in overweight and obese women, but did not improve all related indicators.
DIABETES METABOLIC SYNDROME AND OBESITY-TARGETS AND THERAPY
(2021)
Article
Food Science & Technology
Arjun Ghimire, Niraj Paudel, Ranjana Poudel
Summary: The study showed that pomegranate peel extract from the Ganesh variety significantly improved the preservation of ground buffalo meat under refrigeration at 4 degrees C, effectively controlling Peroxide value, TBARS value, and total plate count, thereby extending the shelf life of the meat.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Carla Luis, Andre P. Sousa, Raquel Costa, Ana T. Maduro, Patrick J. Pais, Sara Sa, Alvaro Gestoso, Flavia Fernandes, Eliana Jeronimo, Raquel Soares, Ruben Fernandes, Pilar Baylina, Maria F. Duarte
Summary: The objective of this work is to evaluate the influence of pomegranate peel extract on the behavior of breast cell lines and related oxidative metabolism. The results showed that pomegranate peel extract has anti-proliferation and anti-migration effects on tumor cells, with minor effects on normal epithelial cells. Additionally, pomegranate peel extract affects the activity of antioxidant enzymes in tumor cells.
APPLIED SCIENCES-BASEL
(2023)
Article
Biochemistry & Molecular Biology
Sainan Zhou, Qing Zhang, Yuan Gao, Fang Liu, Wanxiu Cao, Zhaojie Li, Changhu Xue, Qingjuan Tang
Summary: The combination of Sargassum fusiforme with extracts of fruit and vegetable showed anti-obesity potential in obese mice by reducing lipid levels and fat accumulation. Among the supplements, Sargassum fusiforme together with turmeric extract and pomegranate peel extract exhibited the strongest efficacy in regulating adipocytokines and lipid metabolism gene expression. Furthermore, this combination also alleviated the imbalance of intestinal flora caused by a high-fat diet.
Article
Nutrition & Dietetics
Bartosz Fotschki, Ewelina Cholewinska, Katarzyna Ognik, Michal Sojka, Joanna Milala, Joanna Fotschki, Wieslaw Wiczkowski, Jerzy Juskiewicz
Summary: The required amount of berry polyphenols for health benefits is difficult to achieve through fresh fruit consumption, suggesting polyphenol-rich extracts as a dietary alternative. This study fed rats high-fat diets supplemented with 0.1 or 0.3% raspberry polyphenols and found that the higher dose of extract had more noticeable health-promoting effects, including reduced white adipose tissue weight, hepatic triglyceride content, and plasma IL-6 concentration, as well as increased acetic acid concentration in the cecal digesta. The enhanced content of ellagitannin and anthocyanin metabolites in the blood plasma of rats administered the high dose extract may partially explain these effects.
Article
Chemistry, Applied
Maria Jose de Figueiredo, Cristiani Viegas Brandao Grisi, Angela Maria Santiago, Erica de Andrade Vieira, Angela Maria Tribuzy de Magalhaes Cordeiro, Anderson Ferreira Vilela, Arianne Dantas Viana, Solange de Sousa, Libia de Sousa Conrado
Summary: This research evaluated the antioxidant, antimicrobial, and toxicity potential of Croton blanchetianus Baill leaf extract, finding high phenolic content and activity against various microorganisms but toxicity against brine shrimp. Heating treatment reduced toxicity while maintaining phenolic content and antioxidant activity. Packaging with ExCb helped preserve lamb rib quality and prevent lipid oxidation during refrigerated storage.
Article
Biochemistry & Molecular Biology
Xin Li, Licong Yang, Jingen Li, Lezhen Lin, Guodong Zheng
Summary: The study found that Smilax china L. flavonoid (SCF) can help slow down obesity and lipid metabolism disorders, potentially through enhancing the adiponectin receptor/AMPK signaling pathway and improving gut microbiota composition.
Article
Chemistry, Multidisciplinary
Matthew Flavel, Timothy P. Ellis, Lauren Stahl, Denovan Begg, Jason Smythe, Leodevico L. Ilag, Richard S. Weisinger, Barry Kitchen, Markandeya Jois
Summary: This study found that feeding high-fat, high-carbohydrate diets supplemented with polyphenols extracted from sugar cane can reduce body weight and adipose tissue accumulation in mice. The mechanism behind this weight loss is likely due to reduced carbohydrate absorption, leading to a decrease in body weight.
APPLIED SCIENCES-BASEL
(2021)
Article
Agriculture, Multidisciplinary
Haidan Shi, Xuezhi Li, Chen Hou, Li Chen, Yuhuan Zhang, Jianke Li
Summary: Pomegranate peel polyphenols (PPPs) combined with inulin have lipid-lowering effects, reducing body weight and lipid levels while improving gut microbiota and metabolite profiles. These findings demonstrate the anti-obesity effect of PPPs.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Isabel Torres-Cuevas, Ivan Millan, Miguel Asensi, Maximo Vento, Camille Oger, Jean-Marie Galano, Thierry Durand, Angel L. Ortega
Summary: The loss of redox homeostasis induced by hyperglycemia is a key factor in the development of diabetic retinopathy, and pterostilbene has been shown to be effective in preventing diabetic retinopathy by inhibiting lipid peroxidation. In addition to restoring lipid peroxidation levels in diabetes, pterostilbene can also serve as a suitable biomarker for diabetic retinopathy by proposing the use of a derivative of adrenic acid.
Article
Public, Environmental & Occupational Health
Simin Darvish Noori Kalaki, Fatemeh Darabi, Mohammed I. M. Gubari, Mehdi Yaseri, Mohammad Esmail Motlagh, Ramin Heshmat, Mostafa Qorbani, Michael E. Jones, Saeed Safari, Alireza Baratloo, Masoud Baikpour, Mahmoud Yousefifard, Mostafa Hosseini, Roya Kelishadi
Summary: Based on the 2017 AAP guidelines, the prevalence of hypertension in Iranian children was 14.7%, with slightly higher rates in boys compared to girls.
IRANIAN JOURNAL OF PUBLIC HEALTH
(2023)
Review
Respiratory System
Hayley A. Scott, Shawn H. M. Ng, Rebecca F. McLoughlin, Sarah R. Valkenborghs, Parameswaran Nair, Alexandra C. Brown, Olivia R. Carroll, Jay C. Horvat, Lisa G. Wood
Summary: This review examined the association between obesity and airway/systemic inflammation and adipokine levels in adults with asthma. The results showed that obese asthmatics have a different pattern of inflammation compared to non-obese asthmatics. Further mechanistic studies and investigations into the clinical relevance of this altered inflammatory response are warranted.
Article
Nutrition & Dietetics
Lily M. Williams, Bronwyn S. Berthon, Isobel L. Stoodley, Evan J. Williams, Lisa G. Wood
Summary: Medicinal mushroom extracts (MMEs) have immunomodulatory effects on innate immunity. This study examined the influence of MMEs on immune cell responses to inflammatory stimuli in older adults. The extracts showed differential effects on the release of inflammatory and antiviral mediators in vitro.
Article
Ophthalmology
Kia Bayat, Kiana Hassanpour, Hamideh Sabbaghi, Sahba Fekri, Narsis Daftarian, Tahmineh Motevasseli, Fatemeh Suri, Bahareh Kheiri, Mehdi Yaseri, Hamid Ahmadieh
Summary: The purpose of this study was to evaluate the choroidal structure in patients with inherited retinal diseases (IRDs) by investigating the choroidal vascularity index (CVI). The results showed that the CVI of IRD patients was significantly lower than that of healthy individuals matched for age and sex.
INTERNATIONAL JOURNAL OF RETINA AND VITREOUS
(2023)
Letter
Nutrition & Dietetics
Elham Alipoor, Shima Jazayeri, Mostafa Dahmardehei, Shiva Salehi, Mehdi Yaseri, Mohammad Reza Emami, Seyed Mahdi Rezayat, Mohammad Javad Hosseinzadeh-Attar
CLINICAL NUTRITION
(2023)
Article
Biochemistry & Molecular Biology
Elham Alipoor, Mohammad Javad Hosseinzadeh-Attar, Ali Vasheghani-Farahani, Mahnaz Salmani, Mahsa Rezaei, Zahra Namkhah, Monireh Ahmadpanahi, Yaser Jenab, Mohammad Alidoosti, Mehdi Yaseri
Summary: This study investigated the relationship between circulating NRG4 and irisin and cardiometabolic risk factors with CAD risk and severity. The results showed that NRG4 and irisin may be associated with the severity of coronary stenosis.
Article
Ophthalmology
Amirreza Ramezani, Hamideh Sabbaghi, Marzieh Katibeh, Hamid Ahmadieh, Bahareh Kheiri, Mehdi Yaseri, Siamak Moradian, Yousef Alizadeh, Reza Soltani Moghadam, Abdolreza Medghalchi, Koorosh Etemad, Hassan Behboudi
Summary: This study aimed to report the prevalence and associated factors of cataract among the Iranian population in Gilan Province. A population-based cross-sectional study was conducted on residents aged ≥ 50 years old. The study found that older age and history of previous ocular surgery were associated with higher prevalence of cataract, while longer exposure to sunlight was associated with lower prevalence.
INTERNATIONAL OPHTHALMOLOGY
(2023)
Article
Audiology & Speech-Language Pathology
Maziar Khorshidi, Nematollah Rouhbakhsh, Farzaneh Fatahi, Nasrin Yazdani, Mehdi Yaseri, Saeid Aarabi
Summary: This study investigated the impact of Words-in-Noise (WIN) training on speech perception in children with unilateral hearing loss. The results showed that WIN training improved word identification in noise and some electrophysiological parameters in these children. Therefore, WIN training can partially solve speech comprehension problems with noise in this population.
AUDITORY AND VESTIBULAR RESEARCH
(2023)
Meeting Abstract
Nutrition & Dietetics
S. R. Valkenborghs, L. G. Wood, R. Callister, J. W. Upham, C. L. Grainge, S. Anderson, L. M. Williams, R. F. McLoughlin, E. J. Williams, H. A. Scott
PROCEEDINGS OF THE NUTRITION SOCIETY
(2023)
Meeting Abstract
Nutrition & Dietetics
E. J. Williams, L. G. Wood, L. R. Dowling, S. Stanton, K. J. Baines
PROCEEDINGS OF THE NUTRITION SOCIETY
(2023)
Meeting Abstract
Nutrition & Dietetics
E. J. Williams, B. Smith, A. L. Pillar, K. Daly, J. R. Mayall, J. C. Horvat, L. G. Wood
PROCEEDINGS OF THE NUTRITION SOCIETY
(2023)
Meeting Abstract
Nutrition & Dietetics
L. M. Williams, B. S. Berthon, I. L. Stoodley, E. J. Williams, L. G. Wood
PROCEEDINGS OF THE NUTRITION SOCIETY
(2023)
Meeting Abstract
Nutrition & Dietetics
B. S. Berthon, C. A. Thompson, H. A. Scott, P. G. Gibson, L. G. Wood
PROCEEDINGS OF THE NUTRITION SOCIETY
(2023)
Review
Ophthalmology
Seyed Mohamadmehdi Moshtaghion, Mohammad Abolhosseini, Mehdi Yaseri, Seyed Bagher Hosseini, Mozhgan Rezaei Kanavi
Summary: The purpose of this study was to determine the diagnostic accuracy of confocal scan for Acanthamoeba keratitis (AK) and fungal keratitis (FK). The results of the meta-analysis showed that confocal scan had acceptable performance in diagnosing both AK and FK.
INTERNATIONAL OPHTHALMOLOGY
(2023)
Article
Health Policy & Services
Akram Yazdani, Hojjat Zeraati, Shahpar Haghighat, Ahmad Kaviani, Mehdi Yaseri
Summary: This study used a censored quantile regression model to examine the impact of prognostic factors on survival time in breast cancer patients. It confirmed the control effect of heterogeneity due to treatment differences between medical centers.
HEALTH SERVICES RESEARCH AND MANAGERIAL EPIDEMIOLOGY
(2023)
