Article
Chemistry, Physical
Pouyan Razmshoar, S. Hajir Bahrami, Mohammad Rabiee, Marie Hangouet, Marie Martin, Guy Raffin, Abdelhamid Errachid, Nicole Jaffrezic-Renault
Summary: A novel immunosensor platform utilizing customized chemistry of nanofibers and dendrimers was proposed. PS-PAMAM NFs were successfully produced with smaller diameter, uniform morphology, and more hydrophilic properties, providing a better path for antibody immobilization. PAMAM played a critical role in increasing antibody immobilization without agglomeration.
APPLIED SURFACE SCIENCE
(2022)
Article
Materials Science, Multidisciplinary
Qingsong Li, Chen Ding, Wei Yuan, Ruijie Xie, Xiaomeng Zhou, Yang Zhao, Mei Yu, Zijian Yang, Jing Sun, Qiong Tian, Fei Han, Hanfei Li, Xinping Deng, Guanglin Li, Zhiyuan Liu
Summary: A highly permeable and stretchable conductor based on electrospun fluorine rubber fiber mat is reported, demonstrating high stretchability, strain-insensitivity, and stability for on-skin applications.
ADVANCED FIBER MATERIALS
(2021)
Article
Polymer Science
Chonthicha Iumsrivun, Takayuki Yui, Atsushi Yokoyama, Yuya Ishii
Summary: This study investigated the quasistatic direct electromechanical properties of submicron/micron electrospun fiber mats composed of different polymers. It was found that PMMA, aPS, and PDLLA fiber mats exhibited significant high direct electromechanical responses, while the PVA fiber mat showed minimal response. Furthermore, the direct electromechanical properties of PMMA and aPS fiber mats remained stable even 30 days after fabrication.
Article
Materials Science, Ceramics
Dengsheng Ji, Qin Ouyang, Yanfei Wang, Heng Wang, Hongze Liang, Liu He, Qing Huang
Summary: Flexible and thermal stable SiC fiber mats were prepared from boron-doped polyaluminocarbosilane (PACS) precursor by electro-spinning, curing, and pyrolysis. Two boron-containing compounds, o-carborane (oCB) and phenylboronic acid (PBA), were used as boron sources, and their effects on the properties and structure of the SiC fiber mats were investigated.
CERAMICS INTERNATIONAL
(2023)
Article
Biochemistry & Molecular Biology
Somaye Akbari, Addie Bahi, Ali Farahani, Abbas S. Milani, Frank Ko
Summary: By blending softwood Kraft lignin with polyamidoamine dendritic polymer, bead-free nanofiber mats were successfully produced for the first time, showing enhanced mechanical and thermal characteristics. The chemical interactions between lignin functional groups and amino groups in PAMAM were verified, suggesting potential applications in membranes, filtration, and controlled release drug delivery.
Article
Optics
Nideesh Padiyakkuth, Rodolphe Antoine, Nandakumar Kalarikkal
Summary: The development of novel polymer nanofiber-based photonic devices has led to improved optical materials, extremely appealing for random lasers. Electrospun polymer fibers have been proposed as convenient materials for random lasers, offering a versatile and low-cost strategy for developing new scattering materials. In this study, electrospun PVDF polymer mats doped with R6G dye were utilized to observe the transition from amplified spontaneous emission to lasing with coherent feedback by increasing the gain concentration.
JOURNAL OF LUMINESCENCE
(2022)
Article
Materials Science, Characterization & Testing
Juyeon Kim, Hong Dinh Duong, Jong Il Rhee
Summary: This study fabricated six electrospun fluorescent fiber mats using a temperature-sensitive fluorescent dye and six different polymers. The electrospun fiber mats were characterized as fluorescence temperature sensors and showed good stability, short response time, and good reversibility in aqueous solution (PAN) and high sensitivity and selectivity in air (PMMA). These two mats were tested as non-invasive sensors for measuring temperature in biological and environmental processes.
Article
Biotechnology & Applied Microbiology
Sun Ah Jang, Ji Hyun Park, Hye Jin Lim, Joon Young Oh, Ki Hyeon Bae, Kyung Jin Lee, Jae Kwang Song, Dong-Myung Kim
Summary: By using electrospun polyhydroxybutyrate nanofibers as an alternative support for enzyme immobilization, it is possible to anchor enzymes more efficiently and improve their stability and activity compared to conventional immobilization supports. This approach combines the advantageous features of nanofibrous material and specificity of biomolecular interaction, and can be widely adopted in the development of various enzymatic processes.
ENZYME AND MICROBIAL TECHNOLOGY
(2021)
Article
Chemistry, Applied
Zhouru Li, Wuyin Weng, Zhongyang Ren, Yucang Zhang, Songnan Li, Linfan Shi
Summary: Starch-based nanofiber mats prepared by electrospinning can adsorb the odor of oyster peptides, improving the flavors of marine products.
FOOD HYDROCOLLOIDS
(2022)
Article
Chemistry, Medicinal
Wiphada Rongthong, Nakorn Niamnont, Choladda Srisuwannaket, Nophawan Paradee, Withawat Mingvanish
Summary: The study investigated the preparation conditions and stability of gelatin fiber mats loaded with crude C. carandas fruits ethanol extract, showing that the electrospun gelatin fiber mats prepared under certain conditions have high release efficiency and stability of bioactive compounds.
JOURNAL OF PHARMACEUTICAL SCIENCES
(2021)
Article
Chemistry, Multidisciplinary
Hongmei Wang, Shengbao Duan, Yezhou Chen, Huan Liu, Jingjing Tian, Feiran Wu, Ziqian Du, Longhai Tang, Yong Li, Shaohua Ding
Summary: This study investigates the potential of using a natural silk cocoon membrane as a substrate for immunosensing assays. The membrane exhibits excellent bioactivity and stability, making it a versatile and thermally stable platform for immunoassays.
Article
Chemistry, Physical
Francisco J. Garcia-Mateos, Juana M. Rosas, Ramiro Ruiz-Rosas, Jose Rodriguez-Mirasol, Tomas Cordero
Summary: Functional carbon fibers with high porosity and surface area can be prepared by thermal treatment and doping with phosphoric acid. The presence of phosphorus preserves the porosity of the fibers at high temperature and allows for the development of electrical conductivity.
Review
Pharmacology & Pharmacy
Deepakkumar Mishra, Shilpkala Gade, Varun Pathak, Lalitkumar K. Vora, Kiran Mcloughlin, Reinhold Medina, Ryan F. Donnelly, Thakur Raghu Raj Singh
Summary: The limitations of conventional ocular drug delivery methods have led to the development of novel drug delivery systems using electrospun fibers. These fibers have exceptional structural properties and have gained significant interest in ocular drug delivery and biomaterial applications. This review discusses the recent developments of electrospun fibers for delivering drugs, biologics, cells, growth factors, and tissue regeneration in treating ocular diseases. The review also provides insights into the selection of materials and fabrication techniques for achieving controlled drug release and cell therapy.
DRUG DISCOVERY TODAY
(2023)
Article
Polymer Science
Sarah O. L. Souza, Sergio M. de Oliveira, Luciana M. Silva, Rodrigo L. Orefice
Summary: Photopolymerizable hydrogels based on methacryloyl gelatin (GeIMA) with enhanced mechanical properties and biological activity were prepared by incorporating mats of electrospun polycaprolactone fibers containing GeIMA in GelMA hydrogels. The results showed that the fiber mats within the hydrogels could enhance the biological activity of the materials, thus expanding the usage of biomolecule-based hydrogels in biomedical applications.
JOURNAL OF APPLIED POLYMER SCIENCE
(2022)
Article
Chemistry, Multidisciplinary
Yuliya Kan, Julia Bondareva, Eugene S. Statnik, Julijana Cvjetinovic, Svetlana Lipovskikh, Arkady S. Abdurashitov, Maria A. Kirsanova, Gleb B. Sukhorukhov, Stanislav A. Evlashin, Alexey Salimon, Alexander M. Korsunsky
Summary: This study focuses on the fabrication of core-shell nanofiber mats using electrospinning technique. The core-shell structure was modified with silica nanoparticles and graphene oxide to enhance fiber integrity and stability. The influence of nano additives and crosslinking conditions on fiber diameter, hydrolysis, and mechanical properties were investigated. The results suggest that electrospun core-shell nanofiber mats have great potential for biomedical applications.
Article
Physics, Applied
Bhaskar Das, Syed Minhaz Hossain, Anupam Nandi, Debabrata Samanta, Ashit Kumar Pramanick, Sergio Omar Martinez Chapa, Mallar Ray
Summary: In addition to searching for new materials for next-generation solar cells, improving the efficiency of existing crystalline silicon-based photovoltaic modules is also crucial. This study used a silicon nanocrystal dispersed gel-glass as a luminescent down shifting material to enhance the efficiency of conventional solar cell modules.
JOURNAL OF PHYSICS D-APPLIED PHYSICS
(2022)
Article
Polymer Science
Hamed Hosseinian, Samira Hosseini, Sergio O. Martinez-Chapa, Mazhar Sher
Summary: Wearable contact lenses for medical applications have gained significant attention due to their ability to record physiological information in real-time. These devices are utilized for IOP measurement, glucose detection, ocular drug delivery, and colorblindness treatment. Challenges and shortcomings of current devices are discussed, and the use of electrospun fibers for drug loading and release is highlighted. The transition from clinical trials to real-world applications is also explored.
Article
Chemistry, Analytical
Snehan Peshin, Derosh George, Roya Shiri, Lawrence Kulinsky, Marc Madou
Summary: Compact disc (CD)-based centrifugal microfluidics is a popular choice for portable biological and chemical assays. This study presents two new multiple-use wax valve designs driven by capillary or magnetic forces. The capillary-driven wax valve was analyzed through numerical simulations and experimental results, and the parameters of the valve were measured and analyzed theoretically.
Article
Chemistry, Multidisciplinary
Reyna Berenice Gonzalez-Gonzalez, Lucy Teresa Gonzalez, Marc Madou, Cesar Leyva-Porras, Sergio Omar Martinez-Chapa, Alberto Mendoza
Summary: In this study, carbon dots were synthesized from activated and non-activated pyrolytic carbon black obtained from waste tires and chemically oxidized with HNO3. The effects on carbon dot properties were analyzed using various characterization techniques. The results showed that carbon dots from activated precursors exhibited different photoluminescence properties compared to those from non-activated precursors. Additionally, a dialysis method was proposed to purify the carbon dots.
Article
Nanoscience & Nanotechnology
Vianni Chopra, Jijo Thomas, Gaurav Chauhan, Swati Kaushik, Swati Rajput, Rajdeep Guha, Naibedya Chattopadhyay, Sergio O. Martinez-Chapa, Deepa Ghosh
Summary: By developing a scaffold that mimics the micro-/nano-bone structure, the differentiation of mesenchymal stem cells to osteogenic lineage can be accelerated without the need for exogenous osteogenic supplements. Additionally, the scaffold enhances angiogenesis and exhibits anti-biofilm activity.
ACS APPLIED NANO MATERIALS
(2022)
Article
Biochemical Research Methods
Yujia Liu, Lawrence Kulinsky, Roya Shiri, Marc Madou
Summary: In this study, a novel method of inward pumping using elastic membranes was introduced to centrifugal microfluidic platforms, allowing the liquid to be returned from the periphery to the center of the disk. By controlling the disk's angular velocity and the fluidic resistance in two channels, efficient inward pumping was achieved, demonstrating enhanced fluid mixing and the utility for multi-step assays on the disk.
Article
Chemistry, Analytical
Masoud Madadelahi, Javid Azimi-Boulali, Marc Madou, Sergio Omar Martinez-Chapa
Summary: The fluidic barrier in centrifugal microfluidic platforms is a newly introduced concept that is used for making multiple emulsions and microparticles. This study focuses on the application of particle generation to better understand this method. Theoretical models are used to explain how liquid polymeric droplets pass through a fluidic barrier, and experimental investigations are conducted to explore the effects of different parameters on the size and aspect ratio of the particles. The concept is further extended to two-source fluids, and the importance of source channel geometry, barrier length, and rotational speed in generating two-fluid droplets is studied.
Article
Chemistry, Physical
Albert Cisquella-Serra, Marco Magnani, Marc Madou, Manuel Gamero-Castano
Summary: This article presents a novel technique for building carbon nanofiber composites using chemical vapor deposition (CVD) assisted by Joule heating. The heating of electrospun carbon nanofibers mats, induced by the passing of an electric current through the resistive mat and the associated Joule heating, is studied using infrared thermography. A thermal model is developed to correlate the imposed electrical dissipation and the temperature of the mat, a key variable in CVD. Joule heating is used to decompose W(CO)6 and deposit a coating of WO3-x on all carbon nanofibers without the need of annealing.
Review
Biophysics
Vahid Kordzadeh-Kermani, Masoud Madadelahi, Seyed Nezameddin Ashrafizadeh, Lawrence Kulinsky, Sergio O. Martinez-Chapa, Marc J. Madou
Summary: This review introduces the on-board power supply and electrokinetic applications of electrified-LOD (eLOD) devices. By utilizing electrokinetic phenomena, different microfluids can be propelled, separated, and manipulated. While extensive research exists on stationary platforms, the applications on rotating platforms are still underdeveloped.
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Polymer Science
Ivan Djordjevic, Gautama Wicaksono, Juhi Singh, Manisha Singh, Elizabeth G. Ellis, Maher A. Alraddadi, Andrew P. Dove, Terry W. J. Steele
Summary: In this study, thiol/ene-based resorbable elastomers were combined with a carbene bioadhesive to create a dual crosslinked, three-component hybrid network. The resulting hybrid bioadhesive displayed both tunable dynamic moduli and shear adhesion strength, making it a promising candidate for various biomedical applications.
EUROPEAN POLYMER JOURNAL
(2022)
Article
Chemistry, Analytical
Snehan Peshin, Marc Madou, Lawrence Kulinsky
Summary: Over the past 20 years, numerous immunoassays have been successfully integrated on CD platforms, enabling portable POC platforms with sample-to-answer capabilities. This study demonstrates the simultaneous integration of blood plasma separation (BPS) and reciprocation on a CD platform, allowing for the separation of plasma from red blood cells without inflow into the reciprocation chamber. Experimental results showed that the integrated design had significantly higher fluorescent signal compared to the standard design when the reciprocation time was increased to 7 minutes.
Article
Materials Science, Multidisciplinary
Elizabeth Ellis, Ivan Djordjevic, Muhammad Naziruddin Bin Mohd Ali, Terry W. J. Steele
Summary: Light-activated carbenes provide a unique method of non-specific covalent bond formation needed in bioadhesives and rapid gelation. The behavior of carbene-based bioadhesives in the presence of various liquid additives containing reactive functional groups has been investigated. The results show that different additives have different effects on material properties, such as maintaining storage modulus, reducing viscosity, accelerating hydrolysis, increasing hydrophilicity, and enhancing dynamic modulus.
ACS APPLIED POLYMER MATERIALS
(2023)
Article
Education & Educational Research
Samira Hosseini, Claudia Camacho, Katia Donjuan, Luis Pego, Jose Escamilla
Summary: The COVID-19 outbreak has exposed the vulnerability of our species and society. The delivery of education during the pandemic became a pressing issue, leading to the digitalization of education. However, this highlighted the negative impact on students' mental health. In response, Tecnologico de Monterrey launched the Unplugged Day initiative, which proved to promote students' well-being and offer strategies for addressing mental health issues.
EDUCATION SCIENCES
(2023)
Review
Chemistry, Analytical
Masoud Madadelahi, Marc J. Madou
Summary: The pandemic has provided financial and regulatory support for the improvement of limit of detection (LOD), speed, and cost of important diagnostic tools such as lateral flow assays (LFA), enzyme-linked immunosorbent assays (ELISA), and polymerase chain reaction (PCR). Among these tools, PCR has shown the most progress in overall performance. However, implementing PCR in point of care (POC) settings remains challenging due to strict requirements for low LOD, multiplexing, accuracy, selectivity, robustness, and cost. This article introduces three parameters to guide the design of the next generation of PCR reactors based on POC requirements: the overall sample-to-answer time (t), lambda (?), which determines the minimum number of copies required per reactor volume, and gamma (?), the system's thermal efficiency. Evaluation: 8/10.
Review
Nanoscience & Nanotechnology
Kendra Corral-Najera, Gaurav Chauhan, Sergio O. Serna-Saldivar, Sergio O. Martinez-Chapa, Mohammad Mahdi Aeinehvand
Summary: This article discusses the importance and roles of membranes in organ-on-a-chip (OOC) platforms, including providing support, allowing permeation/exchange of nutrients and relevant molecules through membrane pores, and enabling the delivery of mechanical or chemical stimuli. OOC platforms allow for in vitro study of physiological processes, while membranes in OOCs broaden knowledge of how mechanical and chemical cues affect cells and organs. OOCs with membranes are used as in vitro microfluidic models to replace animal testing for various applications such as drug discovery and disease modeling.
MICROSYSTEMS & NANOENGINEERING
(2023)