期刊
ANNUAL REVIEW OF VIROLOGY, VOL 3
卷 3, 期 -, 页码 453-472出版社
ANNUAL REVIEWS
DOI: 10.1146/annurev-virology-110615-042127
关键词
Escherichia coli; lysis; lysogeny; noise; decision-making; fluorescence microscopy; systems biology
类别
资金
- NIGMS NIH HHS [R01 GM082837] Funding Source: Medline
- Direct For Mathematical & Physical Scien
- Division Of Physics [1147498] Funding Source: National Science Foundation
Studies over more than half a century have resulted in what some consider a complete narrative for the life cycle of bacteriophage.. However, this narrative is only complete within the limited resolution offered by the traditional genetic and biochemical approaches that were used to create it. A recent series of studies performed at the single-cell and single-phage levels has revealed a wealth of previously unknown features. By pointing to many open questions, these new studies highlight the limitations of our current understanding of lambda, but they also initiate the process of forming a more detailed and quantitative narrative for the system.
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