Article
Chemistry, Physical
Lorenza Romagnoli, Andrea D'Annibale, Elena Blundo, Atanu Patra, Antonio Polimeni, Daniele Meggiolaro, Iryna Andrusenko, Danilo Marchetti, Mauro Gemmi, Alessandro Latini
Summary: A new one-dimensional hybrid iodoplumbate with excellent thermal stability and resistance to water and oxygen is reported for the first time. It exhibits strong visible fluorescence under UV irradiation and forms an efficient light-emitting material when combined with PbI2. Extensive characterization and theoretical calculations reveal its potential for applications in light-emitting and photovoltaic devices.
CHEMISTRY OF MATERIALS
(2023)
Article
Chemistry, Physical
Quan Wang, Ning Sui, Xiujun Gao, Xiaochun Chi, Lingyun Pan, Ran Lu, Hanzhuang Zhang, Zhihui Kang, Bing Zhao, Yinghui Wang
Summary: A comparative investigation on the photophysical properties of a quinoxaline derivative QDMA2 was conducted using various spectroscopies. It was found that a solvent-stabilized charge-transfer state plays a role in the relaxation process of excited QDMA2, and the aggregated QDMA2 molecules exhibit a correlated color temperature value in organic light-emitting diode testing. Pressure-dependent photoluminescence of aggregated QDMA2 suggests that intermolecular interactions can impact the color and intensity of photoluminescence by adjusting the band gap and irradiative channel of the molecules.
JOURNAL OF PHYSICAL CHEMISTRY B
(2021)
Article
Chemistry, Applied
Corentin Pigot, Guillaume Noirbent, Thanh-Tuan Bui, Sebastien Peralta, Sylvain Duval, Malek Nechab, Didier Gigmes, Frederic Dumur
Summary: A series of twelve dyes based on the 4,4-bis(4-methoxyphenyl)butadienyl donor have been designed and synthesized, allowing for dyes with absorption wavelengths between 400 and 650 nm. Solvatochromism experiments revealed linear correlations using specific scales and comparisons with reference compounds provided insights into the electron releasing ability of the donor. The variation in absorption maxima of the dyes was found to be more influenced by the polarizability of the solvent rather than its polarity, and theoretical calculations supported the experimental results.
Article
Crystallography
Liang Jiao, Hui Tian, Man Wang, Tianyu Li, Qiong Wu
Summary: The text provides structural information about a molecule, including its composition, crystal structure parameters, and other specific data such as temperature.
ZEITSCHRIFT FUR KRISTALLOGRAPHIE-NEW CRYSTAL STRUCTURES
(2021)
Article
Chemistry, Physical
Raheleh Afzali, Mohammad Vakili, Vahidreza Darugar
Summary: In this study, the structure, spectroscopy, and vibrational analysis of Cu(dmpd)(2) were investigated using density functional theory and experimental techniques, and compared to other copper complexes. The results indicated that the Cu-O bond strength of Cu(dmpd)(2) is close to Cu(bzac)(2) and higher than Cu(tmhd)(2).
JOURNAL OF MOLECULAR STRUCTURE
(2021)
Article
Chemistry, Multidisciplinary
A. Finko, A. Sokolov, L. A. Vasilyeva, D. A. Skvortsov, A. S. H. Al-Khazraji, E. N. Ofitserov, N. Zyk, A. G. Majouga, E. K. Beloglazkina
Summary: New bis(seleno-imidazolone) derivatives bearing alkyl and aryl moieties at the N(1) atom of the five-membered ring were synthesized, and their cytotoxicity against various cell lines was evaluated.
RUSSIAN CHEMICAL BULLETIN
(2021)
Article
Chemistry, Medicinal
Luca Scapinello, Guglielmo Vesco, Luca Nardo, Angelo Maspero, Federico Vavassori, Simona Galli, Andrea Penoni
Summary: The newly synthesized zinc complex exhibits a zincoxane molecular structure with high affinity for hard nucleophiles, especially in interactions with DNA. The complex also shows stability in coordination with DMSO and holds potential for the development of optimized drug substances for anticancer applications.
Article
Multidisciplinary Sciences
Hojat Jafari, Elham Ameri, Majid Rezaeivala, Avni Berisha
Summary: Due to the high anti-corrosion property, accessibility, being eco-friendly and low cost of steel, the use of reduced form of Schiff base (RSH) as a corrosion inhibitor for steel has been investigated. The results show that RSH can effectively inhibit corrosion and the inhibition efficiency increases with the concentration of inhibitor.
ARABIAN JOURNAL FOR SCIENCE AND ENGINEERING
(2023)
Article
Crystallography
Xiao-Ming Chen, Fei Zeng
Summary: This is a structure of C28H32O6, with an orthorhombic crystal system in the Pnma space group, and the parameters are a = 7.752(2) angstrom, b = 29.959(8) angstrom, c = 10.176(3) angstrom. The volume is 2363.5(11) angstrom(3) with 4 molecules in the unit cell. The R-factor (R-gt(F)) is 0.1145 and the weighted R-factor (wR(ref)(F-2)) is 0.1076 at a temperature of 296(2) K.
ZEITSCHRIFT FUR KRISTALLOGRAPHIE-NEW CRYSTAL STRUCTURES
(2023)
Article
Chemistry, Multidisciplinary
Lorenza Romagnoli, Andrea D'Annibale, Elena Blundo, Antonio Polimeni, Alberto Cassetta, Giuseppe Chita, Riccardo Panetta, Andrea Ciccioli, Alessandro Latini
Summary: AEPyBiI, a novel perovskite material, was synthesized with good thermal stability and environmental stability. It exhibits superior photoluminescence properties compared to common InP materials, and its simple synthesis and non-toxic composition make it a promising environmentally friendly light-emitting material.
CRYSTAL GROWTH & DESIGN
(2022)
Article
Crystallography
Rui Duan, Wang Man, Huang Meifen, Xun Ma, Qiong Wu
Summary: The crystal structure of the substance is monoclinic with cell parameters a = 10.2649(3) angstrom, b = 10.1903(3) angstrom, c = 21.2494(6) angstrom, and β = 100.522(1) degrees.
ZEITSCHRIFT FUR KRISTALLOGRAPHIE-NEW CRYSTAL STRUCTURES
(2022)
Article
Crystallography
Baiying Wei, Chenzhong Cao
Summary: This text provides crystallographic data of a compound with molecular formula C17H14Cl2CuN2O2, including its crystal system, lattice parameters, temperature, and other relevant details.
ZEITSCHRIFT FUR KRISTALLOGRAPHIE-NEW CRYSTAL STRUCTURES
(2021)
Article
Chemistry, Physical
Yasmin M. Ahmed, Ashraf M. Ashmawy, M. M. Omar, Ashraf A. Abbas, Sara G. Mostafa, Gehad G. Mohamed
Summary: The goal of this research was to create new ligand-metal complexes and characterize them using various physicochemical techniques. The data from elemental analyses, molar conductivity, magnetic susceptibility, infrared (IR), electronic absorption, 1 H NMR, mass spectral studies, and thermal analysis confirmed the stoichiometry and octahedral geometry of the metal complexes. The complexes showed superior antimicrobial, antioxidant, and anticancer activities compared to the ligand, and the ligand successfully inhibited the corrosion of steel.
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Article
Chemistry, Physical
Vahid Amani, Esmail Owla, Darioush Sharafie
Summary: Metal-organic frameworks (MOFs) have drawn attention for their potential applications in various fields, with a new pillared-layer zinc-organic framework CFU-1 synthesized and characterized for its molecular recognition of nitroaromatics. The study highlights the framework's structural features, stability, and potential for sensing nitro-analytes such as nitrobenzene and 2,4,6-trinitrotoluene.
JOURNAL OF MOLECULAR STRUCTURE
(2021)
Article
Chemistry, Multidisciplinary
Bhagwat T. Vhanale, Avinash T. Shinde
Summary: In this study, the synthesis, characterization, and biological properties of four novel Ni(II) and Fe(III) Schiff base complexes are reported. The complexes were characterized using various techniques, confirming the binding mode of the ligand, the structures of the complexes, and their antibacterial and antioxidant activities.
JOURNAL OF THE IRANIAN CHEMICAL SOCIETY
(2022)
Article
Chemistry, Medicinal
Prashant Kumar, Daniel Pletzer, Evan F. Haney, Negin Rahanjam, John T. J. Cheng, Marty Yue, Waleed Aljehani, Robert E. W. Hancock, Jayachandran N. Kizhakkedathu, Suzana K. Straus
ACS INFECTIOUS DISEASES
(2019)
Review
Chemistry, Multidisciplinary
Evan F. Haney, Suzana K. Straus, Robert E. W. Hancock
FRONTIERS IN CHEMISTRY
(2019)
Article
Biochemistry & Molecular Biology
Nigare Raheem, Prashant Kumar, Ethan Lee, John T. J. Cheng, Robert E. W. Hancock, Suzana K. Straus
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
(2020)
Review
Biochemistry & Molecular Biology
Surajit Bhattacharjya, Suzana K. Straus
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2020)
Article
Chemistry, Medicinal
Hashem Etayash, Daniel Pletzer, Prashant Kumar, Suzana K. Straus, Robert E. W. Hancock
JOURNAL OF MEDICINAL CHEMISTRY
(2020)
Review
Biochemistry & Molecular Biology
Matthew Drayton, Jayachandran N. Kizhakkedathu, Suzana K. Straus
Review
Biochemistry & Molecular Biology
Taylor Rounds, Suzana K. Straus
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2020)
Review
Biochemistry & Molecular Biology
Matthew Drayton, Julia P. Deisinger, Kevin C. Ludwig, Nigare Raheem, Anna Mueller, Tanja Schneider, Suzana K. Straus
Summary: The rapid rise of multidrug-resistant bacteria has raised concerns about the effectiveness of traditional antibiotics. Antimicrobial peptides, with their diverse mechanisms of actions, offer a promising solution to combat these pathogens. This review discusses the mechanisms of antibiotic resistance and the potential of antimicrobial peptides in providing a more robust treatment of bacterial infections.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Chemistry, Multidisciplinary
Matthew Drayton, Morgan A. Alford, Daniel Pletzer, Evan F. Haney, Yoan Machado, Haiming D. Luo, Christopher M. Overall, Jayachandran N. Kizhakkedathu, Robert E. W. Hancock, Suzana K. Straus
Summary: A novel PEG-HDP conjugate was designed targeting MMPs at sites of inflammation and infection, enhancing antimicrobial activity through enzymatic cleavage while improving biocompatibility, demonstrated by strong antibacterial efficacy in a mouse abscess model with high-density MRSA infection.
JOURNAL OF CONTROLLED RELEASE
(2021)
Correction
Chemistry, Medicinal
Hashem Etayash, Morgan Alford, Noushin Akhoundsadegh, Matthew Drayton, Suzana K. Straus, Robert E. W. Hancock
JOURNAL OF MEDICINAL CHEMISTRY
(2022)
Article
Chemistry, Medicinal
Hashem Etayash, Morgan Alford, Noushin Akhoundsadegh, Matthew Drayton, Suzana K. Straus, Robert E. W. Hancock
Summary: A novel vancomycin-innate defense regulator conjugate (V-IDR1018) was developed with multiple functions including bacterial killing, biofilm eradication, and immune modulation. It showed potent antibacterial activity, resistance against antimicrobial resistance, and stimulation of immune responses, making it a valuable candidate for treating complex infectious diseases.
JOURNAL OF MEDICINAL CHEMISTRY
(2021)
Review
Virology
Keng-Shuo Pi, Yurou Sang, Suzana K. Straus
Summary: Multiple sclerosis (MS) is a disease caused by immune system attacks on the protective myelin sheath. Various viruses, including Epstein-Barr virus, human herpesvirus 6, cytomegalovirus, and varicella-zoster virus, have been identified as potential triggering agents for MS. This review examines the specific role of proline-rich proteins encoded by these viruses and their potential molecular role in MS.
Article
Virology
Keng-Shuo Pi, Daria Bortolotti, Yurou Sang, Giovanna Schiuma, Silvia Beltrami, Sabrina Rizzo, Alessandra Bortoluzzi, Eleonora Baldi, A. Louise Creagh, Charles A. Haynes, Roberta Rizzo, Suzana K. Straus
Summary: Multiple studies have suggested a potential link between HHV-6A and multiple sclerosis. The authors conducted experiments to examine hypotheses related to the interactions and roles of U24 protein in HHV-6A in MS.
Article
Infectious Diseases
Felix L. Santana, Karel Estrada, Morgan A. Alford, Bing C. Wu, Melanie Dostert, Lucas Pedraz, Noushin Akhoundsadegh, Pavneet Kalsi, Evan F. Haney, Suzana K. Straus, Gerardo Corzo, Robert E. W. Hancock
Summary: Host defense peptides (HDPs) are an alternative approach to combat antibiotic resistance. Crocodylians have a robust immune system and researchers have discovered novel cathelicidin sequences with broad-spectrum antimicrobial and antibiofilm activities. Among them, As-CATH8 exhibited similar activity profiles to last-resort antibiotics, killed planktonic and biofilm cells, caused cell membrane depolarization and binding to DNA. As-CATH8 also showed superior antibiofilm activity against methicillin-resistant Staphylococcus aureus (MRSA) compared to human cathelicidin LL-37. Moreover, As-CATH8 demonstrated strong antibacterial effects against clinical isolates of S. aureus and Acinetobacter baumannii in a murine abscess model. This study expands the understanding of cathelicidin peptides in crocodylians and highlights the therapeutic potential of As-CATH8 for common skin infections.
Article
Multidisciplinary Sciences
Chanel C. La, Stephanie A. Smith, Sreeparna Vappala, Reheman Adili, Catherine E. Luke, Srinivas Abbina, Haiming D. Luo, Irina Chafeeva, Matthew Drayton, Louise A. A. Creagh, Maria de Guadalupe Jaraquemada-Pelaez, Nicole Rhoads, Manu Thomas Kalathottukaren, Peter K. Henke, Suzana K. Straus, Caigan Du, Edward M. Conway, Michael Holinstat, Charles A. Haynes, James H. Morrissey, Jayachandran N. Kizhakkedathu
Summary: Current treatments for thrombosis prevention are complicated by the risk of bleeding. This study proposes a design concept called macromolecular polyanion inhibitors (MPI) to inhibit polyphosphate (polyP) and reduce bleeding risk. The lead MPI candidates exhibit antithrombotic activity in mouse models without causing bleeding and are well tolerated. This inhibitor has the potential to improve thrombosis prevention without increasing the risk of bleeding.
NATURE COMMUNICATIONS
(2023)