Article
Chemistry, Multidisciplinary
Samuel J. Francis, Marco D. Torelli, Nicholas A. Nunn, Gowthami M. Arepally, Olga A. Shenderova
Summary: Thrombosis is a major health issue in the United States and there is a lack of understanding about its causes, progression, and response to anticoagulant therapy. This study demonstrates the use of fluorescent nanodiamond (FND) as a label for blood clots, which offers advantages over organic fluorophores, such as reduced photodegradation. The addition of tissue plasminogen activator (tPa) allows visualization of clot lysis, which is important for studying the resolution of deep vein thrombosis and pulmonary embolism.
Article
Biochemistry & Molecular Biology
Xin Yu, Xinmiao Ji, Yixiang Fan, Biao Yu, Xinyu Wang, Chuanlin Feng, Lei Zhang, Chao Song, Xin Zhang
Summary: Moderate static magnetic fields (SMFs) can reduce cisplatin-induced kidney toxicity by inhibiting cell death and reducing oxidative stress. This novel physical method shows potential for mitigating the side effects of cisplatin in cancer treatment.
Article
Chemistry, Multidisciplinary
Jelena Lazovic, Eberhard Goering, Anna-Maria Wild, Peter Schuetzenduebe, Anitha Shiva, Jessica Loeffler, Gordon Winter, Metin Sitti
Summary: Nanodiamonds have great potential for diverse applications and can be visualized and tracked using non-invasive imaging techniques. They possess paramagnetic properties that enable them to provide high contrast to noise ratio in MRI for cell labeling and tracking.
ADVANCED MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Virjinia Doltchinkova, Siya Lozanova, Blaga Rukova, Rumin Nikolov, Elitsa Ivanova, Chavdar Roumenin
Summary: This study investigates the effects of static magnetic field (SMF) on the electrokinetic potential and morphological characteristics of erythrocytes in both normal individuals and those with beta-thalassemia. The results show that SMF can alter the electrokinetic potential and morphology of erythrocytes, as well as induce lipid peroxidation. The study also reveals the influence of SMF on the electrostatic free energy of erythrocytes and its correlation with membrane structural-functional state. This research has potential applications in biomedicine.
FRONTIERS IN CHEMISTRY
(2023)
Article
Chemistry, Analytical
Kamlesh Awasthi, Si-Pei Li, Chao-Yuan Zhu, Hsin-Yun Hsu, Nobuhiro Ohta
Summary: Application of nanosecond pulsed electric field (nsPEF) is a promising research area for cancer treatment. In this study, nsPEF with a pulse width of 50 ns and a frequency of 2 kHz was applied to breast cancer cells to induce changes in intracellular function and dynamics. The results showed that nsPEF had different effects on different subtypes of breast cancer cells, leading to apoptosis in one subtype and necrosis in another. Various microscopic measurements confirmed these different modes of nsPEF-induced cell death. This finding provides valuable information for the development of effective cancer therapies.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Multidisciplinary Sciences
E. K. G. D. Ferreira, D. S. D. Lara, G. F. Silveira
Summary: The objective of this study is to evaluate the performance of predictive models using CNN in identifying the number of cells in HCS digital contrast microscopy images. The study found that the number and quality of images significantly affect the predictive ability.
SCIENTIFIC REPORTS
(2023)
Article
Chemistry, Applied
Maciej J. Glowacki, Mateusz Ficek, Miroslaw Sawczak, Anna Wcislo, Robert Bogdanowicz
Summary: This study proposes the use of fluorescent nanodiamonds as stable markers for investigating comestible liquids. By manipulating the composition and pH value of cocktails, the surface chemistry and stability of nanodiamonds can be altered. Nanodiamonds can be applied in monitoring the condition of foodstuffs and detecting toxins and pathogens.
Article
Multidisciplinary Sciences
Alice Sandmeyer, Lili Wang, Wolfgang Huebner, Marcel Mueller, Benjamin K. Chen, Thomas Huser
Summary: Cost-effective, highly portable, and easy to use high-resolution live-cell imaging systems can revolutionize research in challenging environments, enabling real-time tracking of virus particles and studying infection mechanisms.
Article
Environmental Sciences
L. Makinistian, L. Zastko, A. Tvarozna, L. E. Dias, I Belyaev
Summary: Research suggests that the static magnetic field generated by the use of earphones can have a wide range of exposure and potential biological effects on the human body. With no scientific consensus on the possible mechanisms of interaction with living tissues, caution in using earphones may be advisable.
ENVIRONMENTAL RESEARCH
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Felix Eisenhut, Sven-Martin Schlaffer, Stefan Hock, Elisabeth Heynold, Natalia Kremenevski, Ingmar Bluemcke, Michael Buchfelder, Arnd Doerfler, Manuel A. Schmidt
Summary: This study aimed to compare the effectiveness of 7T and 3T ultra-high-field magnetic resonance imaging (MRI) in detecting and localizing pituitary microadenomas. The results showed that 7T MRI outperformed 3T MRI in detecting microadenomas and providing more precise localization, with better image quality. Therefore, 7T sellar imaging is a promising option that can help reduce the need for invasive diagnostics.
INVESTIGATIVE RADIOLOGY
(2022)
Article
Materials Science, Multidisciplinary
Rajakar Selvam, Ashish Gandhi, Shih-Che Hung, Artashes V. Karmenyan, Elena Perevedentseva, Wang-Chi Yeh, Sheng-Yun Wu, Hsin-Hou Chang, Chia-Liang Cheng
Summary: The study utilized magnetic nanodiamond particles as an efficient drug delivery vehicle, conjugated with human serum albumin to improve dispersion in biological medium and facilitate controlled release of drugs. Results showed that when loaded with clinical drug, the particles exhibited significantly improved effectiveness against cancer cells when exposed to a magnetic field.
DIAMOND AND RELATED MATERIALS
(2023)
Article
Biochemical Research Methods
Yuyao Hu, Dong Liang, Jing Wang, Yaping Xuan, Fu Zhao, Jun Liu, Ruxin Li
Summary: The V-HiLo-ED method, based on edge detection, is proposed to remove background noise in fluorescence microscopy imaging. Compared with other software algorithms and hardware methods, V-HiLo-ED performs better in background removal and imaging quality, while also improving the signal-to-noise ratio of images.
JOURNAL OF BIOPHOTONICS
(2022)
Article
Physics, Multidisciplinary
Hiraku Toida, Koji Sakai, Tetsuhiko F. Teshima, Masahiro Hori, Kosuke Kakuyanagi, Imran Mahboob, Yukinori Ono, Shiro Saito
Summary: The authors demonstrate magnetometry of cultured neurons on a polymeric film using a superconducting flux qubit, achieving electron spin resonance spectroscopy. The magnetization signal from the neurons is observed by changing the temperature and magnetic field, and it is identified to originate from iron ions in neurons. This technique can be extended to achieve electron spin resonance spectroscopy at the single-cell level.
COMMUNICATIONS PHYSICS
(2023)
Article
Biochemical Research Methods
Sebastian Acuna, Mayank Roy, Luis E. Villegas-Hernandez, Vishesh K. Dubey, Balpreet Singh Ahluwalia, Krishna Agarwal
Summary: Contrast in fluorescence microscopy images can be increased by exploiting the fluctuation of emitters in a stack of images, yielding results comparable to structured illumination microscopy in tissue samples.
BIOMEDICAL OPTICS EXPRESS
(2021)
Article
Computer Science, Information Systems
Aamir Qamar, Shahid Iqbal, Sadiq Ahmad, Abbas Z. Kouzani, M. A. Parvez Mahmud
Summary: In this paper, a new algorithm based on static electric field and ordered pairs is proposed to draw the configuration of unknown grounding grid. Unlike magnetic field, electric field does not require gradient, and the maximum electric field value indicates the location of grounding conductor, with connections validated by measuring the electric field on the circle.
Article
Neurosciences
Daniele Linaro, Istvan Biro, Michele Giugliano
EUROPEAN JOURNAL OF NEUROSCIENCE
(2018)
Meeting Abstract
Biophysics
Niccolo Paolo Pampaloni, Martin Lottner, Michele Giugliano, Alessia Matmglio, Francesco D'Amico, Maurizio Prato, Jose Antonio Garrido, Laura Ballerini, Denis Scaini
BIOPHYSICAL JOURNAL
(2018)
Article
Nanoscience & Nanotechnology
Niccolo Paolo Pampaloni, Martin Lottner, Michele Giugliano, Alessia Matruglio, Francesco D'Amico, Maurizio Prato, Jose Antonio Garrido, Laura Ballerini, Denis Scaini
NATURE NANOTECHNOLOGY
(2018)
Review
Neurosciences
Niccolo Paolo Pampaloni, Michele Giugliano, Denis Scaini, Laura Ballerini, Rossana Rauti
FRONTIERS IN NEUROSCIENCE
(2019)
Article
Neurosciences
Anastasiya Moskalyuk, Sebastiaan Van De Vijver, Peter Verstraelen, Winnok H. De Vos, R. Frank Kooy, Michele Giugliano
Article
Multidisciplinary Sciences
Sebastiaan Van De Vijver, Stephan Missaulf, Jeroen Van Soom, Pieter Van Der Veken, Koen Augustyns, Jurgen Joossens, Stefanie Dedeurwaerdere, Michele Giugliano
Article
Neurosciences
Daniele Linaro, Gabriel K. Ocker, Brent Doiron, Michele Giugliano
JOURNAL OF NEUROSCIENCE
(2019)
Article
Nanoscience & Nanotechnology
Shashi K. R. Singam, Milos Nesladek, Etienne Goovaerts
Article
Cell Biology
Joana Lourenco, Angela Michela De Stasi, Charlotte Deleuze, Mathilde Bigot, Antonio Pazienti, Andrea Aguirre, Michele Giugliano, Srdjan Ostojic, Alberto Bacci
Article
Neurosciences
Matteo Manzati, Teresa Sorbo, Michele Giugliano, Laura Ballerini
Article
Neurosciences
Peter D. Jones, Anastasiya Moskalyuk, Clemens Barthold, Katja Gutoehrlein, Gerhard Heusel, Birgit Schroeppel, Ramona Samba, Michele Giugliano
FRONTIERS IN NEUROSCIENCE
(2020)
Article
Neurosciences
Stefano Borda Bossana, Christophe Verbist, Michele Giugliano
FRONTIERS IN CELLULAR NEUROSCIENCE
(2020)
Article
Biochemical Research Methods
Christophe Verbist, Michael G. Mueller, Huibert D. Mansvelder, Robert Legenstein, Michele Giugliano
PLOS COMPUTATIONAL BIOLOGY
(2020)
Review
Multidisciplinary Sciences
Richard George, Michela Chiappalone, Michele Giugliano, Timothee Levi, Stefano Vassanelli, Johannes Partzsch, Christian Mayr
Article
Biochemistry & Molecular Biology
Simone Frisari, Manuela Santo, Ali Hosseini, Matteo Manzati, Michele Giugliano, Antonello Mallamaci
Summary: This study functionally evaluated the impact of FOXG1 mutations on neurodevelopmental and physiological processes. The results provide valuable insights into the misregulated processes in FOXG1 syndrome patients and suggest the use of murine pallial cultures for profiling novel FOXG1 mutations.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)