NIK regulates MT1-MMP activity and promotes glioma cell invasion independently of the canonical NF-κB pathway

Hic-5 mediates the initiation of endothelial sprouting by regulating a key surface metalloproteinase

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Membrane-type matrix metalloproteinases: Their functions and regulations

(2015) Yoshifumi Itoh   MATRIX BIOLOGY

Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) promotes glioma cell invasion through induction of NF-κB-inducing kinase (NIK) and noncanonical NF-κB signaling

(2015) Evan M Cherry et al.   Molecular Cancer

Cell shape and the microenvironment regulate nuclear translocation of NF- B in breast epithelial and tumor cells

(2015) J. E. Sero et al.   Molecular Systems Biology

Topological robustness analysis of protein interaction networks reveals key targets for overcoming chemotherapy resistance in glioma

(2015) Hátylas Azevedo et al.   Scientific Reports

NF-κB and STAT3 in glioblastoma: therapeutic targets coming of age

(2014) G Kenneth Gray et al.   Expert Review of Neurotherapeutics

Genomic profiling reveals distinctive molecular relapse patterns inIDH1/2wild-type glioblastoma

(2014) Vera Riehmer et al.   GENES CHROMOSOMES & CANCER

NF-κB Inducing Kinase, a Central Signaling Component of the Non-Canonical Pathway of NF-κB, Contributes to Ovarian Cancer Progression

(2014) Masaya Uno et al.   PLoS One

IHC Profiler: An Open Source Plugin for the Quantitative Evaluation and Automated Scoring of Immunohistochemistry Images of Human Tissue Samples

(2014) Frency Varghese et al.   PLoS One

NF- B, an Active Player in Human Cancers

(2014) Y. Xia et al.   Cancer Immunology Research

The Somatic Genomic Landscape of Glioblastoma

(2013) Cameron W. Brennan et al.   CELL

NIK Controls Classical and Alternative NF- B Activation and Is Necessary for the Survival of Human T-cell Lymphoma Cells

(2013) L. Odqvist et al.   CLINICAL CANCER RESEARCH

A screen for morphological complexity identifies regulators of switch-like transitions between discrete cell shapes

(2013) Zheng Yin et al.   NATURE CELL BIOLOGY

The NF-κB RelB Protein Is an Oncogenic Driver of Mesenchymal Glioma

(2013) Dong Whan Lee et al.   PLoS One

Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

(2013) J. Gao et al.   Science Signaling

Calpain-mediated vimentin cleavage occurs upstream of MT1-MMP membrane translocation to facilitate endothelial sprout initiation

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Trespassing cancer cells: ‘fingerprinting’ invasive protrusions reveals metastatic culprits

(2012) Richard L Klemke   CURRENT OPINION IN CELL BIOLOGY

NF- B, the first quarter-century: remarkable progress and outstanding questions

(2012) M. S. Hayden et al.   GENES & DEVELOPMENT

NF-κB and the link between inflammation and cancer

(2012) Joseph A. DiDonato et al.   IMMUNOLOGICAL REVIEWS

N-WASP coordinates the delivery and F-actin–mediated capture of MT1-MMP at invasive pseudopods

(2012) Xinzi Yu et al.   JOURNAL OF CELL BIOLOGY

The kinase TBK1 controls IgA class switching by negatively regulating noncanonical NF-κB signaling

(2012) Jin Jin et al.   NATURE IMMUNOLOGY

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

Life at the Leading Edge

(2011) Anne J. Ridley   CELL

Inflammation meets cancer, with NF-κB as the matchmaker

(2011) Yinon Ben-Neriah et al.   NATURE IMMUNOLOGY

The 'ins' and 'outs' of podosomes and invadopodia: characteristics, formation and function

(2011) Danielle A. Murphy et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

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(2010) Shao-Cong Sun   CELL RESEARCH

NF-κB inducing kinase: A key regulator in the immune system and in cancer

(2010) Yee Mon Thu et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Overexpression of NF-κB inducing kinase underlies constitutive NF-κB activation in lung cancer cells

(2010) Yasunori Saitoh et al.   LUNG CANCER

CNK1 Promotes Invasion of Cancer Cells through NF- B-Dependent Signaling

(2010) R. D. Fritz et al.   MOLECULAR CANCER RESEARCH

Controlling the Fate of NIK: A Central Stage in Noncanonical NF- B Signaling

(2010) S. C. Sun   Science Signaling

Negative Feedback in Noncanonical NF- B Signaling Modulates NIK Stability Through IKK -Mediated Phosphorylation

(2010) B. Razani et al.   Science Signaling

Modulation of the Membrane Type 1 Matrix Metalloproteinase Cytoplasmic Tail Enhances Tumor Cell Invasion and Proliferation in Three-dimensional Collagen Matrices

(2009) Natalie M. Moss et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A MT1-MMP/NF-κB signaling axis as a checkpoint controller of COX-2 expression in CD133(+) U87 glioblastoma cells

(2009) Borhane Annabi et al.   Journal of Neuroinflammation

Investigating endothelial invasion and sprouting behavior in three-dimensional collagen matrices

(2009) Kayla J Bayless et al.   Nature Protocols

Proliferation of Human Glioblastoma Stem Cells Occurs Independently of Exogenous Mitogens

(2009) John J. P. Kelly et al.   STEM CELLS

Mapping proteolytic cancer cell-extracellular matrix interfaces

(2008) Katarina Wolf et al.   CLINICAL & EXPERIMENTAL METASTASIS

Control of canonical NF- B activation through the NIK-IKK complex pathway

(2008) B. Zarnegar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA