Review
Polymer Science
Zohaib Khurshid, Binoy Mathews Nedumgottil, Ramy Moustafa Moustafa Ali, Sompop Bencharit, Shariq Najeeb
Summary: This study critically analyzed and evaluated PEEK dental prostheses and found that they may provide a viable and more esthetic alternative to conventional prostheses. However, the long-term viability of PEEK prostheses is still uncertain due to limitations in the research.
Article
Dentistry, Oral Surgery & Medicine
Pietro Ausiello, Alessandro Espedito Di Lauro, Joao Paulo Mendes Tribst, David C. Watts
Summary: This study aimed to evaluate the influence of new resin-based CAD-CAM implant-supported materials on posterior crown restoration stress and strain concentrations. The finite element analysis revealed differences in stress distribution among different resin materials. The Estelite P Block material showed lower tensile and shear stresses compared to other resin-based materials.
Article
Materials Science, Multidisciplinary
Ladislav Cvrcek, Jan Krcil, Jana Musilkova, Veronika Musilkova, Lucie Bacakova, Vaclav Nehasil, Frantisek Denk, Zdenek Cejka
Summary: In this study, a PEEK material with a gradient surface topography and suitable chemical composition was prepared by 3D printing and coating with a nanostructured TiNb layer. The surface properties and biological activity were analyzed, and the results showed that the nanostructured TiNb layer significantly improved the biological activity of PEEK.
MATERIALS & DESIGN
(2022)
Review
Biotechnology & Applied Microbiology
Xinming Gu, Xiaolin Sun, Yue Sun, Jia Wang, Yiping Liu, Kaixuan Yu, Yao Wang, Yanmin Zhou
Summary: PEEK has been increasingly used as an implant material due to its biocompatibility, chemical stability, and elastic modulus similar to natural bone, but suffers from poor integration with surrounding bone tissue. Various strategies for functionalizing the surface and changing the structure of PEEK have been proposed to improve its bioactivity. Inspired by bone tissue, this review explores ways to enhance the biocompatibility of PEEK implants and suggests directions for future multifunctional implant fabrication.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Multidisciplinary Sciences
Yomna H. Shash, Mohamed T. El-Wakad, Mohamed A. A. El-Dosoky, Mohamed M. Dohiem
Summary: Fixed prostheses are common treatment options for edentulous patients, but researchers are exploring alternative materials due to limitations of titanium. This study used finite element analysis to evaluate the stress distribution in fixed prostheses with polymeric frameworks and different bone densities. The choice of framework material depended on spongy bone density. Soft frameworks were recommended for low-density cases to reduce stresses on bone tissues.
SCIENTIFIC REPORTS
(2023)
Review
Polymer Science
Shivam Verma, Nitin Sharma, Saurabh Kango, Sumit Sharma
Summary: The review study highlights the progress of PEEK and its composite materials in biomedical applications, showing their potential as alternative materials for conventional implants. PEEK exhibits excellent mechanical and physicochemical properties, contributing to successful applications in dentistry, knee implants, hip replacement, spine implants, and other areas. Further research is needed to optimize techniques and enhance accessibility of PEEK and its composites for broader societal benefits.
EUROPEAN POLYMER JOURNAL
(2021)
Review
Biochemistry & Molecular Biology
Durratul Aqwa Mohd Farid, Nur A'fifah Husna Zahari, Zulfahmi Said, Mohd Ifwat Mohd Ghazali, Lee Hao-Ern, Syazwani Mohamad Zol, Sami Aldhuwayhi, Muhammad Syafiq Alauddin
Summary: This article comprehensively reviews the biomodifications introduced to denture components, particularly denture base material, to improve the overall biological properties. It also explores fundamental information about PMMA as a conventional denture base material and the causative microbial agents for biological threats to dentures.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Materials Science, Multidisciplinary
D. Chopra, K. Gulati, S. Ivanovski
Summary: Nanostructured implants inspired by nature show potential in preventing bacterial infection but require careful consideration of biocompatibility and bioactivity. Further research is needed for the development of advanced biomimetic nano-engineered implants.
MATERIALS TODAY ADVANCES
(2021)
Article
Multidisciplinary Sciences
Hatim Alqurashi, Zohaib Khurshid, Azeem Ul Yaqin Syed, Syed Rashid Habib, Dinesh Rokaya, Muhammad Sohail Zafar
Summary: PEKK is a new evolving polymeric material with good shock absorbance and fracture resistance, showing promising potential in restorative and implant dentistry applications, especially with reduced stress shielding effect in dental implants. Further research and developments are needed to broaden its applications in the field of dentistry.
JOURNAL OF ADVANCED RESEARCH
(2021)
Article
Nanoscience & Nanotechnology
Krishnan Thyagarajan, Rene A. Lujan, Qian Wang, JengPing Lu, Sivkheng Kor, Bruce Kakimoto, Norine Chang, Julie A. Bert
Summary: Advances in neural probes have made intracortical neuromodulation possible through direct electrical stimulation or generating electric fields using time-varying magnetic fields. Current-actuated coils, which require no conductive contact with tissues, offer precise tailoring of magnetic fields and are a more effective technique for intracortical stimulation.
Article
Engineering, Biomedical
Slila Chayanun, Theerapat Chanamuangkon, Budsaraporn Boonsuth, Aldo R. Boccaccini, Boonrat Lohwongwatana
Summary: Polyetheretherketone (PEEK) has become an alternative to conventional metal implants due to its superior mechanical properties and chemical stability. However, its bio-inertness limits its applications. This study combines CO2 laser machining with sulfonation to enhance the bioactivity of PEEK and strengthen the implant-bone interface. The combination treatment shows the highest mineralization and ALP activity, providing a promising pathway for future PEEK-based orthopedic applications.
MATERIALS TODAY BIO
(2023)
Article
Biology
Onur Gonul, Ahmet Cicek, Ibrahim Murat Afat, Emine Tuna Akdogan, Onur Atali
Summary: The aim of this study is to examine the effect of unilaterally more posterior placement of implants according to the all-on-four concept on stress distribution on bone, implants, and other prosthetic components using finite element analysis. The findings suggest that posteriorly placed implants can prevent bone resorption caused by high stress around the crestal bone, but may increase stress on the implants and prosthetic parts.
Article
Medicine, General & Internal
Mustafa Gseibat, Valerio Sorrentino, Pablo Sevilla, Jesus Pelaez, Maria J. Suarez
Summary: This study describes a fully digital workflow using a dual scan impression technique to fabricate immediate fixed complete dentures for zygomatic and standard implants. The technique provides rapid, precise, and aesthetic results, reduces scanning and fabrication time, and improves clinician and patient satisfaction.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Materials Science, Multidisciplinary
Bankole Oladapo, S. Abolfazl Zahedi
Summary: The study created a new composite material using PEEK, cHAp, and rGO to improve biocompatibility and mimic bone structure with different lattice porous structures. The results indicated that the composite with 5% rGO showed higher biocompatibility and mechanical strength, and the addition of rGO significantly increased the Young's modulus and bulk modulus of PEEK.
MATERIALS CHEMISTRY AND PHYSICS
(2021)
Article
Dentistry, Oral Surgery & Medicine
Floor Maarse, Willem M. M. Fennis, Jos W. R. Twisk, Anke Korfage, Hendrik J. Santing, Laurens den Hartog, Marvick S. M. Muradin, Melvin S. Maningky, Gerry M. Raghoebar, Arjan Vissink, Henk S. Brand, Derk Hendrik Jan Jager
Summary: This study aimed to evaluate the clinical performance and patient-reported outcomes of dental implants in dentate patients with primary and secondary Sjogren's syndrome. The results showed that the survival rate and marginal bone-level changes of the implants in these patients were similar to those without Sjogren's syndrome, indicating good clinical performance. However, the oral health-related quality of life and satisfaction of patients with Sjogren's syndrome remained lower.
CLINICAL ORAL IMPLANTS RESEARCH
(2022)
Review
Medicine, General & Internal
Vrushank Patel, Muhammad S. Sadiq, Shariq Najeeb, Zohaib Khurshid, Muhammad S. Zafar, Artak Heboyan
Summary: Dental implants are used to support oral functions and aesthetics by surgically placing prosthetic devices in direct contact with the jawbone. Diabetes mellitus can lead to bone loss around implants. Metformin, an anti-diabetic drug with osteogenic properties, is believed to prevent this bone loss. This systematic review aims to summarize and critically appraise the studies on the effects of metformin on dental implants.
JOURNAL OF TAIBAH UNIVERSITY MEDICAL SCIENCES
(2023)
Article
Dentistry, Oral Surgery & Medicine
Aftab Ahmed Khan, Muhammad Sohail Zafar, Muhammad Amber Fareed, Nawaf Abdulrahman AlMufareh, Faisal Alshehri, Hanan AlSunbul, Lippo Lassila, Sufyan Garoushi, Pekka Kalevi Vallittu
Summary: This review aims to provide insights into adhesion aspects within the components of glass fiber-reinforced composite (FRC) and between resin luting material and FRC construction. The study discusses the fundamentals of semi-interpenetrating polymer network (semi-IPN) based FRCs and their advantages in creating a solid adhesive interface. It also highlights the importance of interfacial adhesion in achieving successful FRC-based dental restorations.
Review
Materials Science, Composites
Dinesh Rokaya, Hans Erling Skallevold, Viritpon Srimaneepong, Anand Marya, Pravin Kumar Shah, Zohaib Khurshid, Muhammad Sohail Zafar, Janak Sapkota
Summary: Shape memory polymers (SMPs) are smart materials that can change and revert to their permanent shape upon external stimulus. They can be divided into four types based on their permanent shape, elasticity origin, and temporary shape fixing mechanism. Recent developments have shown the wide applicability of SMPs in various biomedical applications. This comprehensive analysis discusses the types, mechanisms, functionalities, and biomedical applications of SMPs, as well as their future advancement in the biomedical field.
JOURNAL OF COMPOSITES SCIENCE
(2023)
Article
Education & Educational Research
Narmeen Ahmed, Shaur Sarfaraz, Iram Khursheed, Zohaib Khurshid
Summary: This study introduces a formal near-peer mentoring program and examines its effects on the participants. The results show that after participating in the program, a significant percentage of students felt acclimatized into the university environment, and mentors also experienced a sense of belonging. Therefore, the formal introduction of such programs is beneficial for improving student support in medical institutes.
EDUCATION RESEARCH INTERNATIONAL
(2023)
Article
Biochemistry & Molecular Biology
Farooq Azam, Faheem Ahmad, Sheraz Ahmad, Muhammad Sohail Zafar, Zeynep Ulker
Summary: This study investigates the properties of natural fiber-reinforced composite hydrogel fibers for wound dressing application. Kapok and hemp fibers were used as reinforcements to improve the strength of the hydrogel fibers. The prepared composite hydrogel fibers were characterized using FTIR, SEM, and DSC. The results showed that the reinforcement of the fibers enhanced their strength, with hemp fibers exhibiting better mechanical properties.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Review
Materials Science, Multidisciplinary
Muhammad Saad Shaikh, Muhammad Amber Fareed, Muhammad Sohail Zafar
Summary: Tissue engineering in the orofacial region is focused on utilizing immune complexes or other proteins to activate bioactive components and create natural ground materials and tissue components. Bioactive glass, a promising biomaterial, has been found suitable for various clinical dental applications, including regeneration of hard tissues. This review highlights the favorable properties and recent applications of bioactive glass materials for managing periodontal lesions, emphasizing its potential in repairing bone defects, gum recession, and guiding tissue regeneration. However, further research and clinical trials are needed to validate the potential and translate the use of bioactive glass in dental clinics for periodontology.
Letter
Medicine, General & Internal
Giath Gazal, Muhammad S. Zafar
JOURNAL OF TAIBAH UNIVERSITY MEDICAL SCIENCES
(2023)
Article
Materials Science, Composites
Zahra Shafqat, Nadia Munir, Naveed Inayat, Muhammad Adnan Khan, Muhammad Amber Fareed, Muhammad Sohail Zafar
Summary: This study aimed to evaluate the bioactivity of novel remineralizing dental composites loaded with calcium phosphate fillers and chlorhexidine. The results showed that the experimental groups containing higher calcium phosphate fillers (CP10 and CP15) exhibited the deposition of calcium phosphate on their surface after 28 days. This indicates that the addition of calcium phosphate fillers enhances the bioactivity of the composites.
JOURNAL OF COMPOSITES SCIENCE
(2023)
Article
Engineering, Biomedical
Meshal Muhammad Naeem, Huma Sarwar, Aliza Nisar, Shahbaz Ahmed, Juzer Shabbir, Zohaib Khurshid, Paulo J. Palma
Summary: The application of intracanal medicaments such as calcium hydroxide and propolis can affect the physical properties of root dentine. This study compared the effects of propolis and calcium hydroxide on the microhardness of root dentine. It was found that propolis increased the microhardness over time, while calcium hydroxide decreased it.
JOURNAL OF FUNCTIONAL BIOMATERIALS
(2023)
Review
Engineering, Multidisciplinary
Shaqayeq Ramezanzade, Mahsa Aeinehvand, Heliya Ziaei, Zohaib Khurshid, Seied Omid Keyhan, Hamid R. Fallahi, James C. Melville, Morvarid Saeinasab, Farshid Sefat
Summary: This review aimed to evaluate the reliability and efficacy of tissue-engineered composite grafts in the reconstruction of large maxillofacial defects. A systematic review of the literature was conducted, and a total of 13 eligible papers were included. The results showed that tissue-engineered composite grafts can successfully reconstruct large maxillofacial bony defects in short-term follow-ups.
Review
Polymer Science
Ahmed Yaseen Alqutaibi, Abdulmajeed Baik, Sarah A. Almuzaini, Ahmed E. Farghal, Ahmad Abdulkareem Alnazzawi, Sary Borzangy, Afaf Noman Aboalrejal, Mohammed Hosny AbdElaziz, Ihab Ismail Mahmoud, Muhammad Sohail Zafar
Summary: An ideal denture base must possess good physical and mechanical properties, biocompatibility, and esthetic properties. Polymethyl methacrylate (PMMA) is the most commonly used biomaterial for denture fabrication, but it has limitations and needs improvement. This review comprehensively discusses the types, properties, modifications, applications, and recent developments in denture base materials (DBMs), with a focus on enhancing the physical and mechanical properties of PMMA through chemical modifications and mechanical reinforcement. Specific research is needed to improve the biological properties of DBMs and address adverse reactions to potentially harmful substances.
Review
Biochemistry & Molecular Biology
Ahmed Yaseen Alqutaibi, Abdulbari Aljohani, Abdullah Alduri, Abdulmajid Masoudi, Anas M. Alsaedi, Hesham Mohammed Al-Sharani, Ahmed E. Farghal, Ahmad Abdulkareem Alnazzawi, Afaf Noman Aboalrejal, Abdel-Aleam H. Mohamed, Muhammad Sohail Zafar
Summary: This systematic review examines the bactericidal properties of cold atmospheric plasma (CAP) when used on various dental implant surfaces. The review found that CAP effectively reduces bacterial loads and combats biofilm and plaque formation on implant surfaces, leading to improved outcomes for implant patients.
Letter
Medicine, General & Internal
Giath Gazal, Wael Elmalky, Muhammad S. Zafar
JOURNAL OF TAIBAH UNIVERSITY MEDICAL SCIENCES
(2023)
Review
Medicine, General & Internal
Muhammad Khawaja Hammad Uddin, Muhammad Shahrukh Khan Sadiq, Ashfaq Ahmed, Mariam Khan, Tooba Maniar, Syeda Mamoona Mateen, Bilquees Saba, Syed Muhammad Kashif, Shumaila Usman, Shariq Najeeb, Zohaib Khurshid, Muhammad Sohail Zafar
Summary: Metformin is a versatile drug used for managing type 2 diabetes globally. Recent studies have shown its potential benefits in improving oral conditions, including periodontitis and tooth pulp regrowth. It also has positive effects on osseointegration of dental implants, can inhibit oral squamous cell carcinoma, and even improve orthodontic tooth movement.
JOURNAL OF TAIBAH UNIVERSITY MEDICAL SCIENCES
(2023)
Article
Medicine, General & Internal
Tazeen Zehra, Juzer Shabbir, Naheed Najmi, Arshad Hasan, Arifa Haque, Waqas A. Farooqui, Zohaib Khurshid
Summary: This study aimed to evaluate the thoughts and feelings of dentists viewing posted clinical cases on social media platforms. The majority of dentists felt that this practice could cause personal dissatisfaction and lack of motivation. However, they believed that they possessed the skills and knowledge to replicate the clinical cases, but lacked the necessary equipment.
JOURNAL OF TAIBAH UNIVERSITY MEDICAL SCIENCES
(2023)
