Article
Dentistry, Oral Surgery & Medicine
Mario Romandini, Jessica Berglundh, Jan Derks, Mariano Sanz, Tord Berglundh
Summary: The study aimed to evaluate the diagnostic accuracy of clinical and radiographic evaluations made at a single time point during follow-up. The bone levels observed at 9 years were highly accurate in identifying pronounced bone loss. In the absence of baseline documentation, a secondary case definition based on clinical findings provided the best overall diagnostic accuracy in identifying peri-implantitis cases.
CLINICAL ORAL IMPLANTS RESEARCH
(2021)
Article
Dentistry, Oral Surgery & Medicine
Alberto Monje, Maria Vera, Agustin Munoz-Sanz, Hom-Lay Wang, Jose Nart
Summary: This study investigated the characteristics related to SUP around dental implants and found that the presence and grade of SUP were associated with the prevalence of peri-implantitis and implant features, indicating a close relationship between SUP and the clinical manifestations and influencing factors of peri-implantitis.
JOURNAL OF PERIODONTOLOGY
(2021)
Review
Chemistry, Multidisciplinary
Andrea Butera, Maurizio Pascadopoli, Matteo Pellegrini, Simone Gallo, Paolo Zampetti, Andrea Scribante
Summary: Peri-implant infections are common complications of dental implants, and this review evaluates the changes in oral microbiota associated with peri-implant disease. The study finds similarities and differences between peri-implantitis and periodontitis in microbial composition. The use of probiotics, in combination with mechanical debridement, shows potential for reducing peri-implant pockets. Transcriptomics can provide valuable insights into bacterial virulence factors for the prevention, diagnosis, and treatment of peri-implant pathology.
APPLIED SCIENCES-BASEL
(2022)
Article
Dentistry, Oral Surgery & Medicine
Na Zhou, Haohao Huang, Hui Liu, Qiang Li, Guangwen Yang, Yu Zhang, Meng Ding, Heng Dong, Yongbin Mou
Summary: Analysis showed significant differences in bacterial structures between NH and PM implant groups, with higher relative abundance of Actinomyces and Streptococcus in NH samples. Genera Fusobacterium and Prevotella were identified as potential biomarkers for peri-implant mucositis. Moreover, gram-negative anaerobic bacteria, including Porphyromonas and Prevotella, were more prevalent in samples from patients with periodontitis history, indicating higher risk for peri-implant mucositis.
CLINICAL ORAL INVESTIGATIONS
(2022)
Review
Dentistry, Oral Surgery & Medicine
Lena Freitag, Thomas Spinell, Annika Kroger, Gregor Wuerfl, Michael Lauseker, Reinhard Hickel, Moritz Kebschull
Summary: This study aims to systematically review the impact of titanium particles on oral-related cells by examining changes in molecular signatures. Through a systematic search, 12 eligible publications were identified, and a significant overlap of gene expression in oral-related cells exposed to titanium particles was found in four studies. Changes in immune/inflammatory and stress response processes, as well as toll-like receptor and mitogen-activated protein kinase signaling pathways, were associated with titanium exposure in transcriptome and proteome studies. However, the findings regarding epigenetic changes caused by titanium were inconsistent.
Review
Infectious Diseases
Asma Gasmi Benahmed, Amin Gasmi, Torsak Tippairote, Pavan Kumar Mujawdiya, Oleksandr Avdeev, Yurii Shanaida, Geir Bjorklund
Summary: Dental implants are commonly used to replace lost teeth, and titanium implants have a high success rate. However, there is an increasing risk of peri-implantitis, an inflammatory disease that affects the tissues around the implant. This review highlights the impact of different metabolic conditions on peri-implantitis and emphasizes the importance of considering both local and systemic factors in dental implant procedures and treatment.
Review
Dentistry, Oral Surgery & Medicine
Pedro Diaz, Esther Gonzalo, Luis J. Gil Villagra, Barbara Miegimolle, Maria J. Suarez
Summary: This systematic review estimates the overall prevalence of peri-implantitis and explores the impact of different study designs, function times, and use of probing depth on the prevalence rate. The results show that the prevalence of peri-implantitis is highly variable and the use of probing depth as a diagnostic criterion affects the prevalence data. It is important to identify diagnostic markers for more accurate disease classification.
Review
Medicine, Research & Experimental
Carlos Henrique Alves, Karolayne Larissa Russi, Natalia Conceicao Rocha, Fabio Bastos, Michelle Darrieux, Thais Manzano Parisotto, Raquel Girardello
Summary: In recent decades, there have been significant advances in ortho-aesthetic-functional rehabilitation with the introduction of implantology. However, there is still a percentage of failures in implantology surgeries, mainly due to infections caused by bacterial proliferation, fungi presence, and biofilm formation, leading to peri-implantitis. Various studies have been conducted to explore the interaction between the host-oral microbiome and the development of peri-implantitis. Peri-implantitis is associated with a diversity of bacterial species, with Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia being identified in higher proportions of peri-implantitis samples. In addition, the injury of peri-implant tissue triggers an inflammatory response mediated by the activation of innate immune cells, such as macrophages, dendritic cells, mast cells, and neutrophils. Activation of the host immune system may disrupt the balance of oral microbiota, leading to dysbiosis and the production of various substances that contribute to implant loss.
JOURNAL OF TRANSLATIONAL MEDICINE
(2022)
Article
Dentistry, Oral Surgery & Medicine
Muhammad H. A. Saleh, Hadiya Khurshid, Suncica Travan, Khaled Sinjab, Ali Bushahri, Hom-Lay Wang
Summary: The study found that implants placed in sites with a history of apical surgery do not have an increased risk of implant failure or retrograde peri-implantitis. The incidence of RPI was 20%, with an increased trend in cases of persistent apical periodontitis.
JOURNAL OF PERIODONTOLOGY
(2021)
Review
Medicine, General & Internal
Andrea Roccuzzo, Alexandra Stahli, Alberto Monje, Anton Sculean, Giovanni E. Salvi
Summary: Dental implants are considered a reliable routine procedure for replacing missing teeth, but the presence of peri-implantitis has become a concern due to its negative impact on patients' quality of life. The surgical therapeutic modalities for managing this disorder include indications, contraindications, complexity, predictability, and effectiveness.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Dentistry, Oral Surgery & Medicine
Xindi Wei, Shujiao Qian, Yijie Yang, Jiaji Mo
Summary: Microbiome-based therapies are emerging as promising approaches for the treatment of periodontitis and peri-implantitis. This review summarizes recent progress on four microbiome-based therapies, including probiotics, postbiotics, predatory bacteria and phages, and microbiota transplantation, and provides insights into their therapeutic mechanisms. Challenges in this field are also discussed, emphasizing the need for further attention and investigation.
Article
Dentistry, Oral Surgery & Medicine
J. Martinez-Amargant, B. de Tapia, A. Pascual, J. Takamoli, C. Esquinas, J. Nart, C. Valles
Summary: This study aimed to determine the association between tobacco and peri-implant diseases and investigate patient- and implant-related variables associated with peri-implant diseases. Data from 117 patients treated with implant-supported restorations were analyzed, and the study found that smoke intensity was associated with an increased risk of peri-implant diseases.
CLINICAL ORAL IMPLANTS RESEARCH
(2023)
Article
Medicine, General & Internal
Pablo Galindo-Moreno, Andres Catena, Lucia Lopez-Chaichio, Tiago Borges, Francisco O'Valle, Laura Torrecillas-Martinez, Miguel Padial-Molina
Summary: The aim of this study was to analyze the long-term marginal bone level (MBL) of implants supporting fixed full-arch restoration in patients who had previously lost their dentition due to severe periodontitis. The results showed that dental implants restored with fixed segmented full-arch rehabilitation in patients with a history of severe periodontal disease do not suffer important marginal bone loss if some specific factors are considered, mainly the use of long transmucosal abutments (>= 2 mm).
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Dentistry, Oral Surgery & Medicine
Karin Apaza-Bedoya, Maria Elisa Galarraga-Vinueza, Bruna Barbosa Correa, Frank Schwarz, Marco Aurelio Bianchini, Cesar Augusto Magalhaes Benfatti
Summary: This study assessed the prevalence and risk indicators of peri-implant diseases, and associated specific clinical characteristics with these diseases. In the medium term, peri-implant diseases were correlated with factors inherent to the patient's conditions, presurgical treatment plan, and hygiene maintenance care.
JOURNAL OF PERIODONTOLOGY
(2023)
Review
Dentistry, Oral Surgery & Medicine
Andrea Roccuzzo, Jean-Claude Imber, Giovanni Edoardo Salvi, Mario Roccuzzo
Summary: Peri-implantitis is a common disease characterized by inflammation in the tissues around dental implants, leading to bone loss. Nonideal conditions in implant therapy, such as poor planning and insufficient periodontal therapy, may contribute to its progression. There is a good level of evidence for certain factors, while more research is needed to identify others and their long-term impact on peri-implantitis.
PERIODONTOLOGY 2000
(2023)
Article
Dentistry, Oral Surgery & Medicine
Alexandre Perez, Alfonso Caiazzo, Nicola A. Valente, Paolo Toti, Fortunato Alfonsi, Antonio Barone
CLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH
(2020)
Article
Dentistry, Oral Surgery & Medicine
Simone Verardi, Marco Orsini, Teresa Lombardi, Federico Ausenda, Tiziano Testori, Alessandro Pulici, Francesco Oreglia, Nicola Alberto Valente, Claudio Stacchi
JOURNAL OF PERIODONTOLOGY
(2020)
Article
Environmental Sciences
Guido Galletti, Fortunato Alfonsi, Angelo Raffaele, Nicola Alberto Valente, Sibylle Chatelain, Roni Kolerman, Chiara Cinquini, Stefano Romeggio, Giovanna Iezzi, Antonio Barone
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2020)
Review
Dentistry, Oral Surgery & Medicine
Nicola Alberto Valente, Min Wu, Paolo Toti, Giacomo Derchi, Antonio Barone
INTERNATIONAL JOURNAL OF PROSTHODONTICS
(2020)
Article
Dentistry, Oral Surgery & Medicine
Eugenio Velasco-Ortega, Nicola Alberto Valente, Giovanna Iezzi, Morena Petrini, Giacomo Derchi, Antonio Barone
Summary: Lateral maxillary sinus augmentation is a predictable bone regeneration technique, and its success depends on the surgeon's skill and the characteristics of the biomaterial used. The study found no significant difference in new bone percentage between groups, but the control group had more residual biomaterial and less nonmineralized tissue.
CLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH
(2021)
Review
Endocrinology & Metabolism
Dalia Nourah, Salwa Aldahlawi, Sebastiano Andreana
Summary: This review challenges the concept of one size fits all and critically appraises the evidence for the success or failure rate of dental implants and peri-implant health outcomes in patients with less than optimal glycemic control. Evidence suggests that estimating glycemic control from HbA1c measurement alone is misleading and there is inconsistency in the literature regarding the impact of glycemic control on implant failure. Other risk factors may contribute to the survival of implants in diabetic patients.
CURRENT DIABETES REVIEWS
(2022)
Article
Environmental Sciences
Simone Verardi, Nicola Alberto Valente
Summary: This study retrospectively analyzed the clinical outcomes of a mixed protocol for the regeneration of deep osseous defects in 23 patients with 29 implants affected by peri-implantitis. The combined mechanical-chemical and regenerative decontamination therapy was found to be effective, with improvements in probing depth and bleeding on probing observed over a 2-year follow-up period.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Review
Dentistry, Oral Surgery & Medicine
Lorenzo Mordini, Giuseppe Pio Patianna, Giovanna Laura Di Domenico, Zuhair Natto, Nicola Alberto Valente
Summary: The aim of this systematic review was to evaluate the effect of corticosteroids on postoperative symptoms and complications in lateral maxillary sinus augmentation (MSA) procedures. The study found that there was no significant difference in the occurrence of complications between the two groups treated with or without corticosteroids. However, due to the lack of conclusive data and comparative studies, definitive conclusions cannot be drawn.
CLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH
(2022)
Review
Dentistry, Oral Surgery & Medicine
Federico Ausenda, Emanuele Barbera, Elisabetta Cotti, Eugenio Romeo, Zuhair S. Natto, Nicola Alberto Valente
Summary: This systematic review and meta-analysis analyzed the use of probiotics as an adjunct to non-surgical periodontal therapy in patients with periodontitis. The study found that probiotics provide additional clinical benefits at a clinical, microbiological, and immunological level. However, due to data heterogeneity, the immunological and microbiological findings could only be analyzed descriptively.
JAPANESE DENTAL SCIENCE REVIEW
(2023)
Review
Dentistry, Oral Surgery & Medicine
Nicola Alberto Valente, Vincenzo Marchio, Giuseppe Troiano, Roberta Gasparro, Pierluigi Balice, Gaetano Marenzi, Luigi Laino, Gilberto Sammartino, Giovanna Iezzi, Antonio Barone
Summary: This systematic review aimed to investigate the survival and success rates of implants placed after horizontal bone augmentation compared to narrow-diameter implants placed in native bone. The results showed comparable high survival rates between narrow and standard-diameter implants. However, more randomized controlled trials are needed to support this hypothesis.
INTERNATIONAL JOURNAL OF ORAL IMPLANTOLOGY
(2022)
Article
Dentistry, Oral Surgery & Medicine
Mario Gisotti, Diego Lops, Nicola Alberto Valente
Summary: The esthetic success of implant therapy depends on correct planning and surgical-prosthetic execution. However, anatomical limitations and mucogingival deficiencies can complicate the management of a case. This case report demonstrates how orthodontic therapy and mucogingival surgery can optimize implant positioning and esthetic outcomes.
INTERNATIONAL JOURNAL OF ESTHETIC DENTISTRY
(2022)
Article
Dentistry, Oral Surgery & Medicine
Nicola A. Valente
Summary: This study aimed to quantitatively assess the impact of predatory publishing on a single author over a year, finding that predatory publishing is spreading in the dentistry field and could seriously pollute the scientific evidence that supports dental clinical practice.
MINERVA DENTAL AND ORAL SCIENCE
(2021)
Article
Dentistry, Oral Surgery & Medicine
Manon Rey Lescure, Nicola Alberto Valente, Sibylle Chatelain, Chiara Cinquini, Antonio Barone
Summary: The successful use of L-PRF in two mandibular third molar autotransplantations to replace hopeless first mandibular molars in a growing patient resulted in uneventful healing, absence of infection and mobility in the transplanted teeth, and positive outcomes at a 2-year follow-up.
CASE REPORTS IN DENTISTRY
(2021)
Review
Dentistry, Oral Surgery & Medicine
Riccardo Di Gianfilippo, Nicola Alberto Valente, Paolo Toti, Hom-Lay Wang, Antonio Barone
JOURNAL OF PERIODONTAL AND IMPLANT SCIENCE
(2020)
Proceedings Paper
Engineering, Mechanical
N. A. Valente, R. A. Caldwell
PROCEEDINGS OF THE ASME INTERNATIONAL DESIGN ENGINEERING TECHNICAL CONFERENCES AND COMPUTERS AND INFORMATION IN ENGINEERING CONFERENCE, 2019, VOL 8
(2020)