Essential amino acid ratios and mTOR affect lipogenic gene networks and miRNA expression in bovine mammary epithelial cells

Development of a model describing regulation of casein synthesis by the mammalian target of rapamycin (mTOR) signaling pathway in response to insulin, amino acids, and acetate

(2016) J.J. Castro et al.   JOURNAL OF DAIRY SCIENCE

Deep sequencing shows microRNA involvement in bovine mammary gland adaptation to diets supplemented with linseed oil or safflower oil

(2015) Ran Li et al.   BMC GENOMICS

MicroRNA-21 is a potential link between non-alcoholic fatty liver disease and hepatocellular carcinoma via modulation of the HBP1-p53-Srebp1c pathway

(2015) Heng Wu et al.   GUT

Changes in mammary metabolism in response to the provision of an ideal amino acid profile at 2 levels of metabolizable protein supply in dairy cows: Consequences on efficiency

(2015) M.N. Haque et al.   JOURNAL OF DAIRY SCIENCE

Effects of short- and long-chain fatty acids on the expression of stearoyl-CoA desaturase and other lipogenic genes in bovine mammary epithelial cells

(2013) A. A. A. Jacobs et al.   Animal

miR-27a suppresses triglyceride accumulation and affects gene mRNA expression associated with fat metabolism in dairy goat mammary gland epithelial cells

(2013) Xian-zi Lin et al.   GENE

Isoleucine, leucine, methionine, and threonine effects on mammalian target of rapamycin signaling in mammary tissue

(2013) S.I. Arriola Apelo et al.   JOURNAL OF DAIRY SCIENCE

Effects of AMP-activated protein kinase (AMPK) signaling and essential amino acids on mammalian target of rapamycin (mTOR) signaling and protein synthesis rates in mammary cells

(2013) J.A.D.R.N. Appuhamy et al.   JOURNAL OF DAIRY SCIENCE

Functional Role of PPARs in Ruminants: Potential Targets for Fine-Tuning Metabolism during Growth and Lactation

(2013) Massimo Bionaz et al.   PPAR Research

Transcriptional regulation of lipid synthesis in bovine mammary epithelial cells by sterol regulatory element binding protein-1

(2012) L. Ma et al.   JOURNAL OF DAIRY SCIENCE

Rumen-protected lysine, methionine, and histidine increase milk protein yield in dairy cows fed a metabolizable protein-deficient diet

(2012) C. Lee et al.   JOURNAL OF DAIRY SCIENCE

Milk protein responses in dairy cows to changes in postruminal supplies of arginine, isoleucine, and valine

(2012) M.N. Haque et al.   JOURNAL OF DAIRY SCIENCE

Regulation of lipid synthesis by liver X receptor α and sterol regulatory element-binding protein 1 in mammary epithelial cells

(2012) C. Oppi-Williams et al.   JOURNAL OF DAIRY SCIENCE

Major involvement of mTOR in the PPARγ-induced stimulation of adipose tissue lipid uptake and fat accretion

(2012) Pierre-Gilles Blanchard et al.   JOURNAL OF LIPID RESEARCH

Isoleucine and Leucine Independently Regulate mTOR Signaling and Protein Synthesis in MAC-T Cells and Bovine Mammary Tissue Slices

(2012) J. A. D. Ranga Niroshan Appuhamy et al.   JOURNAL OF NUTRITION

Dataset integration identifies transcriptional regulation of microRNA genes by PPARγ in differentiating mouse 3T3-L1 adipocytes

(2012) Elisabeth John et al.   NUCLEIC ACIDS RESEARCH

A new role of p53 in regulating lipid metabolism

(2012) Xingwu Wang et al.   Journal of Molecular Cell Biology

mTOR Complex 1 Regulates Lipin 1 Localization to Control the SREBP Pathway

(2011) Timothy R. Peterson et al.   CELL

MicroRNA regulation in mammalian adipogenesis

(2011) Josue M Romao et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Essential Amino Acids Regulate Both Initiation and Elongation of mRNA Translation Independent of Insulin in MAC-T Cells and Bovine Mammary Tissue Slices

(2011) J. A. D. Ranga Niroshan Appuhamy et al.   JOURNAL OF NUTRITION

Integration of insulin and amino acid signals that regulate hepatic metabolism-related gene expression in rainbow trout: role of TOR

(2010) Marine Lansard et al.   AMINO ACIDS

Activation of liver X receptor (LXR) enhances de novo fatty acid synthesis in bovine mammary epithelial cells

(2010) J.W. McFadden et al.   JOURNAL OF DAIRY SCIENCE

L-Leucine, L-Methionine, and L-Lysine Are Involved in the Regulation of Intermediary Metabolism-Related Gene Expression in Rainbow Trout Hepatocytes

(2010) Marine Lansard et al.   JOURNAL OF NUTRITION

miR-130 Suppresses Adipogenesis by Inhibiting Peroxisome Proliferator-Activated Receptor   Expression

(2010) E. K. Lee et al.   MOLECULAR AND CELLULAR BIOLOGY

Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis

(2010) Shijie Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

microRNA miR-27b impairs human adipocyte differentiation and targets PPARγ

(2009) Michael Karbiener et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Role of adenosine monophosphate-activated protein kinase-p70 ribosomal S6 kinase-1 pathway in repression of liver X receptor-alpha-dependent lipogenic gene induction and hepatic steatosis by a novel class of dithiolethiones

(2009) Seong Hwan Hwahng et al.   HEPATOLOGY

Peroxisome proliferator-activated receptor-γ activation and long-chain fatty acids alter lipogenic gene networks in bovine mammary epithelial cells to various extents

(2009) A.K.G. Kadegowda et al.   JOURNAL OF DAIRY SCIENCE

Gene networks driving bovine milk fat synthesis during the lactation cycle

(2008) Massimo Bionaz et al.   BMC GENOMICS

SREBP Activity Is Regulated by mTORC1 and Contributes to Akt-Dependent Cell Growth

(2008) Thomas Porstmann et al.   Cell Metabolism

Negative effects of the amino acids Lys, His, and Thr on S6K1 phosphorylation in mammary epithelial cells

(2008) Rotem Ladovsky Prizant et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

MicroRNA-373 induces expression of genes with complementary promoter sequences

(2008) R. F. Place et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA