标题
The Role of ATRX in the Alternative Lengthening of Telomeres (ALT) Phenotype
作者
关键词
-
出版物
Genes
Volume 7, Issue 9, Pages 66
出版商
MDPI AG
发表日期
2016-09-19
DOI
10.3390/genes7090066
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- High-resolution telomere fluorescence in situ hybridization reveals intriguing anomalies in germ cell tumors
- (2016) Mohammed Talha Shekhani et al. HUMAN PATHOLOGY
- The prognostic impact of TERT promoter mutations in glioblastomas is modified by the rs2853669 single nucleotide polymorphism
- (2016) Rui Batista et al. INTERNATIONAL JOURNAL OF CANCER
- ATRX loss promotes tumor growth and impairs nonhomologous end joining DNA repair in glioma
- (2016) Carl Koschmann et al. Science Translational Medicine
- TERT promoter mutations in pancreatic endocrine tumours are rare and mainly found in tumours from patients with hereditary syndromes
- (2016) João Vinagre et al. Scientific Reports
- Telomere sister chromatid exchange and the process of aging
- (2016) Krastan B. Blagoev et al. Aging-US
- Depletion of Ku70/80 reduces the levels of extrachromosomal telomeric circles and inhibits proliferation of ALT cells
- (2016) Baomin Li et al. Aging-US
- Leiomyosarcoma With Alternative Lengthening of Telomeres Is Associated With Aggressive Histologic Features, Loss of ATRX Expression, and Poor Clinical Outcome
- (2015) Jau-Yu Liau et al. AMERICAN JOURNAL OF SURGICAL PATHOLOGY
- Loss of ATRX Suppresses Resolution of Telomere Cohesion to Control Recombination in ALT Cancer Cells
- (2015) Mahesh Ramamoorthy et al. CANCER CELL
- Alternative lengthening of telomeres phenotype in malignant vascular tumors is highly associated with loss of ATRX expression and is frequently observed in hepatic angiosarcomas
- (2015) Jau-Yu Liau et al. HUMAN PATHOLOGY
- Comprehensive screening of alternative lengthening of telomeres phenotype and loss of ATRX expression in sarcomas
- (2015) Jau-Yu Liau et al. MODERN PATHOLOGY
- Alternative lengthening of telomeres and loss of ATRX are frequent events in pleomorphic and dedifferentiated liposarcomas
- (2015) Jen-Chieh Lee et al. MODERN PATHOLOGY
- Telomerase activation by genomic rearrangements in high-risk neuroblastoma
- (2015) Martin Peifer et al. NATURE
- SMARCAL1 maintains telomere integrity during DNA replication
- (2015) Lisa A. Poole et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Alternative lengthening of telomeres renders cancer cells hypersensitive to ATR inhibitors
- (2015) R. L. Flynn et al. SCIENCE
- Suppression of the alternative lengthening of telomere pathway by the chromatin remodelling factor ATRX
- (2015) David Clynes et al. Nature Communications
- ATRX represses alternative lengthening of telomeres
- (2015) Christine E. Napier et al. Oncotarget
- Intratumoral diversity of telomere length in individual neuroblastoma tumors
- (2015) Annalisa Pezzolo et al. Oncotarget
- TCEAL7 Inhibition of c-Myc Activity in Alternative Lengthening of Telomeres Regulates hTERT Expression
- (2015) Kyle Lafferty-Whyte et al. NEOPLASIA
- Telomerase inhibition abolishes the tumorigenicity of pediatric ependymoma tumor-initiating cells
- (2014) Mark Barszczyk et al. ACTA NEUROPATHOLOGICA
- Alternative lengthening of telomeres is enriched in, and impacts survival of TP53 mutant pediatric malignant brain tumors
- (2014) Joshua Mangerel et al. ACTA NEUROPATHOLOGICA
- Telomerase-Dependent and Independent Telomere Maintenance and its Clinical Implications in Medullary Thyroid Carcinoma
- (2014) Na Wang et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Alternative Lengthening of Telomeres Predicts Site of Origin in Neuroendocrine Tumor Liver Metastases
- (2014) Epameinondas Dogeas et al. JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
- Rapid induction of alternative lengthening of telomeres by depletion of the histone chaperone ASF1
- (2014) Roderick J O'Sullivan et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- ATRX Dysfunction Induces Replication Defects in Primary Mouse Cells
- (2014) David Clynes et al. PLoS One
- WRN Loss Induces Switching of Telomerase-Independent Mechanisms of Telomere Elongation
- (2014) April Renee Sandy Gocha et al. PLoS One
- TERT promoter mutations in primary and secondary glioblastomas
- (2013) Naosuke Nonoguchi et al. ACTA NEUROPATHOLOGICA
- Distribution of TERT promoter mutations in pediatric and adult tumors of the nervous system
- (2013) Christian Koelsche et al. ACTA NEUROPATHOLOGICA
- Alpha Thalassemia/Mental Retardation Syndrome X-linked Gene Product ATRX Is Required for Proper Replication Restart and Cellular Resistance to Replication Stress
- (2013) Justin Wai-Chung Leung et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Atrx deficiency induces telomere dysfunction, endocrine defects, and reduced life span
- (2013) L. Ashley Watson et al. JOURNAL OF CLINICAL INVESTIGATION
- Methylation of the TERT promoter and risk stratification of childhood brain tumours: an integrative genomic and molecular study
- (2013) Pedro Castelo-Branco et al. LANCET ONCOLOGY
- Chromophobe hepatocellular carcinoma with abrupt anaplasia: a proposal for a new subtype of hepatocellular carcinoma with unique morphological and molecular features
- (2013) Laura D Wood et al. MODERN PATHOLOGY
- The alternative lengthening of telomere phenotype is significantly associated with loss of ATRX expression in high-grade pediatric and adult astrocytomas: a multi-institutional study of 214 astrocytomas
- (2013) Malak Abedalthagafi et al. MODERN PATHOLOGY
- TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal
- (2013) P. J. Killela et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The chromatin remodeller ATRX: a repeat offender in human disease
- (2013) David Clynes et al. TRENDS IN BIOCHEMICAL SCIENCES
- Molecular and Morphologic Correlates of the Alternative Lengthening of Telomeres Phenotype in High-Grade Astrocytomas
- (2012) Doreen N. Nguyen et al. BRAIN PATHOLOGY
- Antitelomerase Therapy Provokes ALT and Mitochondrial Adaptive Mechanisms in Cancer
- (2012) Jian Hu et al. CELL
- Molecular Pathways: Understanding the Role of Rad52 in Homologous Recombination for Therapeutic Advancement
- (2012) B. H. Lok et al. CLINICAL CANCER RESEARCH
- SMARCAL1 catalyzes fork regression and Holliday junction migration to maintain genome stability during DNA replication
- (2012) R. Betous et al. GENES & DEVELOPMENT
- Variant repeats are interspersed throughout the telomeres and recruit nuclear receptors in ALT cells
- (2012) Dimitri Conomos et al. JOURNAL OF CELL BIOLOGY
- Compromised genomic integrity impedes muscle growth after Atrx inactivation
- (2012) Michael S. Huh et al. JOURNAL OF CLINICAL INVESTIGATION
- Alternative mechanisms of telomere lengthening: Permissive mutations, DNA repair proteins and tumorigenic progression
- (2012) April Renee Sandy Gocha et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
- (2012) Jeremy Schwartzentruber et al. NATURE
- Well-differentiated pancreatic neuroendocrine tumors: from genetics to therapy
- (2012) Roeland F. de Wilde et al. Nature Reviews Gastroenterology & Hepatology
- Telomere maintenance mechanisms in malignant peripheral nerve sheath tumors: expression and prognostic relevance
- (2012) L. Venturini et al. NEURO-ONCOLOGY
- RAD52 inactivation is synthetically lethal with deficiencies in BRCA1 and PALB2 in addition to BRCA2 through RAD51-mediated homologous recombination
- (2012) B H Lok et al. ONCOGENE
- Loss of ATRX, Genome Instability, and an Altered DNA Damage Response Are Hallmarks of the Alternative Lengthening of Telomeres Pathway
- (2012) Courtney A. Lovejoy et al. PLoS Genetics
- Telomerase-Independent Paths to Immortality in Predictable Cancer Subtypes
- (2012) Stephen T Durant Journal of Cancer
- Prevalence of the Alternative Lengthening of Telomeres Telomere Maintenance Mechanism in Human Cancer Subtypes
- (2011) Christopher M. Heaphy et al. AMERICAN JOURNAL OF PATHOLOGY
- Telomerase activity in pleural malignant mesotheliomas
- (2011) Amy Y.M. Au et al. LUNG CANCER
- Combinatorial readout of histone H3 modifications specifies localization of ATRX to heterochromatin
- (2011) Sebastian Eustermann et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Altered Telomeres in Tumors with ATRX and DAXX Mutations
- (2011) C. M. Heaphy et al. SCIENCE
- DAXX/ATRX, MEN1, and mTOR Pathway Genes Are Frequently Altered in Pancreatic Neuroendocrine Tumors
- (2011) Y. Jiao et al. SCIENCE
- Prognostic relevance of ALT-associated markers in liposarcoma: a comparative analysis
- (2010) Lorenza Venturini et al. BMC CANCER
- ATRX: Put Me on Repeat
- (2010) Iestyn Whitehouse et al. CELL
- Distinct Factors Control Histone Variant H3.3 Localization at Specific Genomic Regions
- (2010) Aaron D. Goldberg et al. CELL
- ATR-X Syndrome Protein Targets Tandem Repeats and Influences Allele-Specific Expression in a Size-Dependent Manner
- (2010) Martin J. Law et al. CELL
- Assaying and investigating Alternative Lengthening of Telomeres activity in human cells and cancers
- (2010) Jeremy D. Henson et al. FEBS LETTERS
- The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3
- (2010) P. Drane et al. GENES & DEVELOPMENT
- Presence of Alternative Lengthening of Telomeres Mechanism in Patients With Glioblastoma Identifies a Less Aggressive Tumor Type With Longer Survival
- (2010) Kerrie L. McDonald et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Purified human BRCA2 stimulates RAD51-mediated recombination
- (2010) Ryan B. Jensen et al. NATURE
- Alternative lengthening of telomeres: models, mechanisms and implications
- (2010) Anthony J. Cesare et al. NATURE REVIEWS GENETICS
- Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres
- (2010) P. W. Lewis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PML Nuclear Bodies
- (2010) V. Lallemand-Breitenbach et al. Cold Spring Harbor Perspectives in Biology
- Telomere length maintenance – an ALTernative mechanism
- (2009) N.J. Royle et al. CYTOGENETIC AND GENOME RESEARCH
- Structural basis for recognition of H3K4 methylation status by the DNA methyltransferase 3A ATRX–DNMT3–DNMT3L domain
- (2009) Junji Otani et al. EMBO REPORTS
- The annealing helicase SMARCAL1 maintains genome integrity at stalled replication forks
- (2009) C. E. Bansbach et al. GENES & DEVELOPMENT
- Telomere-Maintenance Mechanisms in Soft-Tissue Malignant Fibrous Histiocytomas
- (2009) Toshihiro Matsuo et al. JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
- The alternative lengthening of telomeres phenotype in breast carcinoma is associated with HER-2 overexpression
- (2009) Andrea Proctor Subhawong et al. MODERN PATHOLOGY
- DNA C-circles are specific and quantifiable markers of alternative-lengthening-of-telomeres activity
- (2009) Jeremy D Henson et al. NATURE BIOTECHNOLOGY
- Telomere recombination requires the MUS81 endonuclease
- (2009) Sicong Zeng et al. NATURE CELL BIOLOGY
- Stabilization of quadruplex DNA perturbs telomere replication leading to the activation of an ATR-dependent ATM signaling pathway
- (2009) Angela Rizzo et al. NUCLEIC ACIDS RESEARCH
- FEN1 contributes to telomere stability in ALT-positive tumor cells
- (2009) A Saharia et al. ONCOGENE
- Alternative lengthening of telomeres frequently occurs in mismatch repair system-deficient gastric carcinoma
- (2008) Yasuhiro Omori et al. CANCER SCIENCE
- Telomere dysfunction promotes genome instability and metastatic potential in a K-ras p53 mouse model of lung cancer
- (2008) Samanthi A. Perera et al. CARCINOGENESIS
- Multiple Mechanisms of Telomere Maintenance Exist and Differentially Affect Clinical Outcome in Diffuse Malignant Peritoneal Mesothelioma
- (2008) R. Villa et al. CLINICAL CANCER RESEARCH
- Evaluation of Telomere Length Maintenance Mechanisms in Adrenocortical Carcinoma
- (2008) Tobias Else et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
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