Cynaropicrin: A Comprehensive Research Review and Therapeutic Potential As an Anti-Hepatitis C Virus Agent

Synthesis of cynaropicrin- d 4

(2015) Takuya Sato et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Discovery and resupply of pharmacologically active plant-derived natural products: A review

(2015) Atanas G. Atanasov et al.   BIOTECHNOLOGY ADVANCES

Gram-Scale Purification of Two Sesquiterpene Lactones from Chartolepsis Intermedia Boiss.

(2015) A. S. Adekenova et al.   CHROMATOGRAPHIA

The Effect of Ginger (Zingiber officinalis) and Artichoke (Cynara cardunculus) Extract Supplementation on Functional Dyspepsia: A Randomised, Double-Blind, and Placebo-Controlled Clinical Trial

(2015) Attilio Giacosa et al.   Evidence-based Complementary and Alternative Medicine

Pharmacological Studies of Artichoke Leaf Extract and Their Health Benefits

(2015) Maryem Ben Salem et al.   PLANT FOODS FOR HUMAN NUTRITION

Accumulation of cynaropicrin in globe artichoke and localization of enzymes involved in its biosynthesis

(2015) K. Eljounaidi et al.   PLANT SCIENCE

Sesquiterpene Lactones from Cynara cornigera: Acetyl Cholinesterase Inhibition and In Silico Ligand Docking

(2015) Mohamed-Elamir Hegazy et al.   PLANTA MEDICA

Cynaropicrin attenuates UVB-induced oxidative stress via the AhR–Nrf2–Nqo1 pathway

(2015) Kenjiro Takei et al.   TOXICOLOGY LETTERS

Cynara scolymus affects malignant pleural mesothelioma by promoting apoptosis and restraining invasion

(2015) Claudio Pulito et al.   Oncotarget

Antitrypanosomal structure–activity-relationship study of synthetic cynaropicrin derivatives

(2014) Toyonobu Usuki et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Genotoxic Anti-Cancer Agents and Their Relationship to DNA Damage, Mitosis, and Checkpoint Adaptation in Proliferating Cancer Cells

(2014) Lucy Swift et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Structure-Activity Relationship Study of Sesquiterpene Lactones and Their Semi-Synthetic Amino Derivatives as Potential Antitrypanosomal Products

(2014) Stefanie Zimmermann et al.   MOLECULES

Cytochrome P450s from Cynara cardunculus L. CYP71AV9 and CYP71BL5, catalyze distinct hydroxylations in the sesquiterpene lactone biosynthetic pathway

(2014) Kaouthar Eljounaidi et al.   PLANT SCIENCE

Activities of Psilostachyin A and Cynaropicrin against Trypanosoma cruziIn VitroandIn Vivo

(2013) Cristiane França da Silva et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Specific inhibition of hepatitis C virus entry into host hepatocytes by fungi-derived sulochrin and its derivatives

(2013) Syo Nakajima et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cynaropicrin targets the trypanothione redox system in Trypanosoma brucei

(2013) Stefanie Zimmermann et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Mild oxidative stress induces S-glutathionylation of STAT3 and enhances chemosensitivity of tumoural cells to chemotherapeutic drugs

(2013) Elena Butturini et al.   FREE RADICAL BIOLOGY AND MEDICINE

Lipophilic Extracts of Cynara cardunculus L. var. altilis (DC): A Source of Valuable Bioactive Terpenic Compounds

(2013) Patrícia A. B. Ramos et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Chinese herbal medicine-derived compounds for cancer therapy: A focus on hepatocellular carcinoma

(2013) Yangyang Hu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Secondary metabolites from the aerial parts of Centaurea pannonica (Heuff.) Simonk. from Serbia and their chemotaxonomic importance

(2013) Tanja Milošević Ifantis et al.   PHYTOCHEMISTRY

Antiprotozoal Screening of 60 South African Plants, and the Identification of the Antitrypanosomal Germacranolides Schkuhrin I and II

(2013) Tsholofelo Mokoka et al.   PLANTA MEDICA

Significance of endangered and threatened plant natural products in the control of human disease

(2013) M. A. Ibrahim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NF-κB pathway activators as potential ageing biomarkers: targets for new therapeutic strategies

(2013) Carmela R Balistreri et al.   Immunity & Ageing

Efficacy of Artichoke Dry Extract in Patients with Hyperlipoproteinemia

(2012) Werner Englisch et al.   ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH

Cynaropicrin from Cynara scolymus L. suppresses photoaging of skin by inhibiting the transcription activity of nuclear factor-kappa B

(2012) Yuka Tsuda Tanaka et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Cytotoxic sesquiterpene lactones and other constituents of Centaurea omphalotricha

(2012) El Hadj Kolli et al.   JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY

Genetic mapping and characterization of the globe artichoke (+)-germacrene A synthase gene, encoding the first dedicated enzyme for biosynthesis of the bitter sesquiterpene lactone cynaropicrin

(2012) Barbara Menin et al.   PLANT SCIENCE

Cynaropicrin: The First Plant Natural Product withIn VivoActivity againstTrypanosoma brucei

(2012) Stefanie Zimmermann et al.   PLANTA MEDICA

Quantitative HPLC determination of cynaropicrin in Centaurea Scabiosa dry extract

(2011) I. P. Kaminskii et al.   PHARMACEUTICAL CHEMISTRY JOURNAL

In vitroScreening of Traditional South African Malaria Remedies againstTrypanosoma brucei rhodesiense, Trypanosoma cruzi, Leishmania donovani, andPlasmodium falciparum

(2011) Tsholofelo Mokoka et al.   PLANTA MEDICA

Quantification of Cynaropicrin in Artichoke Leaf Extracts by1H NMR Spectroscopy

(2011) Valerio Pieri et al.   PLANTA MEDICA

Effects of Artichoke Leaf Extract on Acute Gastric Mucosal Injury in Rats

(2010) Kazuo Ishida et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Hepatitis C virus NS5A protein increases hepatic lipid accumulation via induction of activation and expression of PPARgamma

(2009) KyeongJin Kim et al.   FEBS LETTERS

The heat shock protein inhibitor Quercetin attenuates hepatitis C virus production

(2009) Oscar Gonzalez et al.   HEPATOLOGY

Nonstructural 3/4A protease of hepatitis C virus activates epithelial growth factor-induced signal transduction by cleavage of the T-cell protein tyrosine phosphatase

(2009) Erwin Daniel Brenndörfer et al.   HEPATOLOGY

Hepatitis C virus cell entry: role of lipoproteins and cellular receptors

(2009) M. E. Burlone et al.   JOURNAL OF GENERAL VIROLOGY

Peptidomimetic Therapeutic Agents Targeting the Protease Enzyme of the Human Immunodeficiency Virus and Hepatitis C Virus

(2008) Youla S. Tsantrizos   ACCOUNTS OF CHEMICAL RESEARCH

Guaiane Sesquiterpene Lactones and Amino Acid-Sesquiterpene Lactone Conjugates from the Aerial Parts ofSaussurea pulchella

(2008) Min Cheol Yang et al.   JOURNAL OF NATURAL PRODUCTS

Supercritical fluid extraction of cynaropicrin and 20-hydroxyecdysone fromLeuzea carthamoides DC

(2008) Helena Sovová et al.   JOURNAL OF SEPARATION SCIENCE