Synthesis, Biodistribution and In vitro Evaluation of Brain Permeable High Affinity Type 2 Cannabinoid Receptor Agonists [11C]MA2 and [18F]MA3

Development of a High-Affinity PET Radioligand for Imaging Cannabinoid Subtype 2 Receptor

(2016) Rareş-Petru Moldovan et al.   JOURNAL OF MEDICINAL CHEMISTRY

Discovery of a fluorinated 4-oxo-quinoline derivative as a potential positron emission tomography radiotracer for imaging cannabinoid receptor type 2

(2016) Roger Slavik et al.   JOURNAL OF NEUROCHEMISTRY

Synthesis, radiolabeling and evaluation of novel 4-oxo-quinoline derivatives as PET tracers for imaging cannabinoid type 2 receptor

(2015) Roger Slavik et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, in vitro and in vivo evaluation of 1,3,5-triazines as cannabinoid CB2 receptor agonists

(2015) Sari Yrjölä et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Synthesis and preliminary evaluation of [18F]-labeled 2-oxoquinoline derivatives for PET imaging of cannabinoid CB2 receptor

(2012) Nashaat Turkman et al.   NUCLEAR MEDICINE AND BIOLOGY

Synthesis, in vitro and in vivo evaluation of fluorine-18 labelled FE-GW405833 as a PET tracer for type 2 cannabinoid receptor imaging

(2011) Nele Evens et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Preclinical evaluation of [11C]NE40, a type 2 cannabinoid receptor PET tracer

(2011) Nele Evens et al.   NUCLEAR MEDICINE AND BIOLOGY

Synthesis and biodistribution of [11C]A-836339, a new potential radioligand for PET imaging of cannabinoid type 2 receptors (CB2)

(2010) Andrew G. Horti et al.   BIOORGANIC & MEDICINAL CHEMISTRY

CB2: a cannabinoid receptor with an identity crisis

(2010) Brady K Atwood et al.   BRITISH JOURNAL OF PHARMACOLOGY

Characterization of active and inactive states of CB1 receptor and the differential binding state modulation by cannabinoid agonists, antagonists and inverse agonists

(2010) Srinivas Gullapalli et al.   NEUROPHARMACOLOGY

Microglial CB2 cannabinoid receptors are neuroprotective in Huntington's disease excitotoxicity

(2009) Javier Palazuelos et al.   BRAIN

Emerging role of the cannabinoid receptor CB2 in immune regulation: therapeutic prospects for neuroinflammation

(2009) Guy A. Cabral et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Cannabinoid CB2receptor agonists protect the striatum against malonate toxicity: Relevance for Huntington's disease

(2009) Onintza Sagredo et al.   GLIA

Synthesis and biological evaluation of carbon-11- and fluorine-18-labeled 2-oxoquinoline derivatives for type 2 cannabinoid receptor positron emission tomography imaging

(2009) Nele Evens et al.   NUCLEAR MEDICINE AND BIOLOGY

PET radiotracers: crossing the blood–brain barrier and surviving metabolism

(2009) Victor W. Pike   TRENDS IN PHARMACOLOGICAL SCIENCES

Structural modifications of N-arylamide oxadiazoles: Identification of N-arylpiperidine oxadiazoles as potent and selective agonists of CB2

(2008) Erin F. DiMauro et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Discovery and Optimization of a Novel Series ofN-Arylamide Oxadiazoles as Potent, Highly Selective and Orally Bioavailable Cannabinoid Receptor 2 (CB2) Agonists

(2008) Yuan Cheng et al.   JOURNAL OF MEDICINAL CHEMISTRY

Cannabinoid Receptors: Where They are and What They do

(2008) K. Mackie   JOURNAL OF NEUROENDOCRINOLOGY

Labelling and biological evaluation of [11C]methoxy-Sch225336: a radioligand for the cannabinoid-type 2 receptor

(2008) Nele Evens et al.   NUCLEAR MEDICINE AND BIOLOGY

Improved synthesis and metabolic stability analysis of the dopamine transporter ligand [18F]FECT

(2007) Satish K. Chitneni et al.   NUCLEAR MEDICINE AND BIOLOGY