A Recombinant Human Pluripotent Stem Cell Line Stably Expressing Halide-Sensitive YFP-I152L for GABAAR and GlyR-Targeted High-Throughput Drug Screening and Toxicity Testing

Activation of Strychnine-Sensitive Glycine Receptors by Shilajit on Preoptic Hypothalamic Neurons of Juvenile Mice

(2016) Janardhan Prasad Bhattarai   CHINESE JOURNAL OF PHYSIOLOGY

Is the time right for in vitro neurotoxicity testing using human iPSC-derived neurons?

(2016) Anke Tukker   ALTEX-Alternatives to Animal Experimentation

A portable low-cost long-term live-cell imaging platform for biomedical research and education

(2015) Maria P. Walzik et al.   BIOSENSORS & BIOELECTRONICS

The Concise Guide to PHARMACOLOGY 2015/16: Ligand-gated ion channels

(2015) Stephen PH Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

GABAA receptor-acting neurosteroids: A role in the development and regulation of the stress response

(2015) Benjamin G. Gunn et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Reversing excitatory GABAAR signaling restores synaptic plasticity and memory in a mouse model of Down syndrome

(2015) Gabriele Deidda et al.   NATURE MEDICINE

The human epilepsy mutation GABRG2(Q390X) causes chronic subunit accumulation and neurodegeneration

(2015) Jing-Qiong Kang et al.   NATURE NEUROSCIENCE

Glycine receptors control the generation of projection neurons in the developing cerebral cortex

(2014) A Avila et al.   CELL DEATH AND DIFFERENTIATION

Ionotropic GABA and glycine receptor subunit composition in human pluripotent stem cell-derived excitatory cortical neurones

(2014) Owain T. James et al.   JOURNAL OF PHYSIOLOGY-LONDON

Neurobehavioural effects of developmental toxicity

(2014) Philippe Grandjean et al.   LANCET NEUROLOGY

Developmental neurotoxicity – Challenges in the 21st Century and In Vitro Opportunities

(2014) Lena Smirnova   ALTEX-Alternatives to Animal Experimentation

Presynaptic GABAergic inhibition regulated by BDNF contributes to neuropathic pain induction

(2014) Jeremy Tsung-chieh Chen et al.   Nature Communications

Labeling of neuronal differentiation and neuron cells with biocompatible fluorescent nanodiamonds

(2014) Tzu-Chia Hsu et al.   Scientific Reports

The impact of human hyperekplexia mutations on glycine receptor structure and function

(2014) Anna Bode et al.   Molecular Brain

GABAAReceptor Subtypes: Therapeutic Potential in Down Syndrome, Affective Disorders, Schizophrenia, and Autism

(2013) Uwe Rudolph et al.   Annual Review of Pharmacology and Toxicology

Human Ntera2 cells as a predictive in vitro test system for developmental neurotoxicity

(2013) Michael Stern et al.   ARCHIVES OF TOXICOLOGY

Australian marine sponge alkaloids as a new class of glycine-gated chloride channel receptor modulator

(2013) Walter Balansa et al.   BIOORGANIC & MEDICINAL CHEMISTRY

miRNA expression profiling in a human stem cell-based model as a tool for developmental neurotoxicity testing

(2013) Giorgia Pallocca et al.   CELL BIOLOGY AND TOXICOLOGY

A human pluripotent carcinoma stem cell-based model for in vitro developmental neurotoxicity testing: Effects of methylmercury, lead and aluminum evaluated by gene expression studies

(2013) Incoronata Laurenza et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Pathophysiological Mechanisms of Dominant and Recessive GLRA1 Mutations in Hyperekplexia

(2013) S.-K. Chung et al.   JOURNAL OF NEUROSCIENCE

Sesterterpene glycinyl-lactams: a new class of glycine receptor modulator from Australian marine sponges of the genus Psammocinia

(2013) Walter Balansa et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Fluorescence-Based High-Throughput Functional Profiling of Ligand-Gated Ion Channels at the Level of Single Cells

(2013) Sahil Talwar et al.   PLoS One

Glycine Receptor α2 Subunit Activation Promotes Cortical Interneuron Migration

(2013) Ariel Avila et al.   Cell Reports

Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors

(2012) Wei Xiong et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Ion channels and tranporters in cancer. 2. Ion channels and the control of cancer cell migration

(2011) Vishnu Anand Cuddapah et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Mechanism of action of the insecticides, lindane and fipronil, on glycine receptor chloride channels

(2011) Robiul Islam et al.   BRITISH JOURNAL OF PHARMACOLOGY

Inhibitory Synaptic Regulation of Motoneurons: A New Target of Disease Mechanisms in Amyotrophic Lateral Sclerosis

(2011) Lee J. Martin et al.   MOLECULAR NEUROBIOLOGY

Neuropharmacological properties of neurons derived from human stem cells

(2011) Leanne Coyne et al.   NEUROCHEMISTRY INTERNATIONAL

The human ubiquitin C promoter drives selective expression in principal neurons in the brain of a transgenic mouse line

(2011) Franziska Wilhelm et al.   NEUROCHEMISTRY INTERNATIONAL

Ircinialactams: Subunit-selective glycine receptor modulators from Australian sponges of the family Irciniidae

(2010) Walter Balansa et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Contributions of the environment and environmentally vulnerable physiology to autism spectrum disorders

(2010) Martha R Herbert   CURRENT OPINION IN NEUROLOGY

Exon-skipping Splice Variants of Excitatory Amino Acid Transporter-2 (EAAT2) Form Heteromeric Complexes with Full-length EAAT2

(2010) Florian M. Gebhardt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutations in GABAAreceptor subunits associated with genetic epilepsies

(2010) Robert L. Macdonald et al.   JOURNAL OF PHYSIOLOGY-LONDON

Anti-inflammatory role of glycine in reducing rodent postoperative inflammatory ileus

(2010) B. Stoffels et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Differential expression of glycine receptor subunit messenger RNA in the rat following spinal cord injury

(2010) A Esmaeili et al.   SPINAL CORD

Multiplexed labeling of viable cells for high-throughput analysis of glycine receptor function using flow cytometry

(2009) Daniel F. Gilbert et al.   CYTOMETRY PART A

Splice-specific roles of glycine receptor α3 in the hippocampus

(2009) Sabrina A. Eichler et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Discovering new glycine receptor modulators and their binding sites

(2009) Daniel F. Gilbert   Frontiers in Molecular Neuroscience

Human in vitro reporter model of neuronal development and early differentiation processes

(2008) Sebastien Couillard-Despres et al.   BMC NEUROSCIENCE

The insecticide fipronil and its metabolite fipronil sulphone inhibit the rat α1β2γ2L GABAA receptor

(2008) P Li et al.   BRITISH JOURNAL OF PHARMACOLOGY

A Retrospective Performance Assessment of the Developmental Neurotoxicity Study in Support of OECD Test Guideline 426

(2008) Susan L. Makris et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Glycinergic tonic inhibition of hippocampal neurons with depolarizing GABAergic transmission elicits histopathological signs of temporal lobe epilepsy

(2008) Sabrina A. Eichler et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Native glycine receptor subtypes and their physiological roles

(2008) Joseph W. Lynch   NEUROPHARMACOLOGY

GABAA receptors: Subtypes provide diversity of function and pharmacology

(2008) Richard W. Olsen et al.   NEUROPHARMACOLOGY

Subunit-specific potentiation of recombinant glycine receptors by NV-31, a bilobalide-derived compound

(2008) Joseph W. Lynch et al.   NEUROSCIENCE LETTERS

Differentiating human NT2/D1 neurospheres as a versatile in vitro 3D model system for developmental neurotoxicity testing

(2008) E.J. Hill et al.   TOXICOLOGY