Mass spectral determination of phosphopantetheinylation specificity for carrier proteins in Mycobacterium tuberculosis

AcpM, the Meromycolate Extension Acyl Carrier Protein of Mycobacterium tuberculosis, Is Activated by the 4′-Phosphopantetheinyl Transferase PptT, a Potential Target of the Multistep Mycolic Acid Biosynthesis

(2015) Oren Zimhony et al.   BIOCHEMISTRY

A covalent adduct of MbtN, an acyl-ACP dehydrogenase fromMycobacterium tuberculosis, reveals an unusual acyl-binding pocket

(2015) Ai-Fen Chai et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structure, Biochemistry, and Inhibition of Essential 4′-Phosphopantetheinyl Transferases from Two Species of Mycobacteria

(2014) Christopher R. Vickery et al.   ACS Chemical Biology

Crystal structure of the essential Mycobacterium tuberculosis phosphopantetheinyl transferase PptT, solved as a fusion protein with maltose binding protein

(2014) James Jung et al.   JOURNAL OF STRUCTURAL BIOLOGY

Production of recombinant proteins inMycobacterium smegmatisfor structural and functional studies

(2014) Ghader Bashiri et al.   PROTEIN SCIENCE

Mechanism and Regulation of Mycobactin Fatty Acyl-AMP Ligase FadD33

(2013) Olivia Vergnolle et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Detection of soluble co-factor dependent protein expression in vivo : Application to the 4′-phosphopantetheinyl transferase PptT from Mycobacterium tuberculosis

(2013) Karine Rottier et al.   JOURNAL OF STRUCTURAL BIOLOGY

The phosphopantetheinyl transferases: catalysis of a post-translational modification crucial for life

(2013) Joris Beld et al.   NATURAL PRODUCT REPORTS

4′-Phosphopantetheinyl Transferase PptT, a New Drug Target Required for Mycobacterium tuberculosis Growth and Persistence In Vivo

(2013) Cécile Leblanc et al.   PLoS Pathogens

Structural characterization and comparison of three acyl-carrier-protein synthases from pathogenic bacteria

(2012) Andrei S. Halavaty et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Analyses of MbtB, MbtE, and MbtF Suggest Revisions to the Mycobactin Biosynthesis Pathway in Mycobacterium tuberculosis

(2012) M. D. McMahon et al.   JOURNAL OF BACTERIOLOGY

Lipidomic discovery of deoxysiderophores reveals a revised mycobactin biosynthesis pathway in Mycobacterium tuberculosis

(2012) C. A. Madigan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mycobacterium tuberculosisacyl carrier protein synthase adopts two different pH-dependent structural conformations

(2011) Kuppan Gokulan et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Rapid and flexible biochemical assays for evaluating 4′-phosphopantetheinyl transferase activity

(2011) Jeremy G. Owen et al.   BIOCHEMICAL JOURNAL

Experimental mapping of soluble protein domains using a hierarchical approach

(2011) Jean-Denis Pedelacq et al.   NUCLEIC ACIDS RESEARCH

Metabolic Engineering of Cofactor F420 Production in Mycobacterium smegmatis

(2010) Ghader Bashiri et al.   PLoS One

Staphylococcus aureus Nonribosomal Peptide Secondary Metabolites Regulate Virulence

(2010) M. A. Wyatt et al.   SCIENCE

Structure–Function Analysis of the Acyl Carrier Protein Synthase (AcpS) from Mycobacterium tuberculosis

(2009) Orly Dym et al.   JOURNAL OF MOLECULAR BIOLOGY