The decapping activator Edc3 and the Q/N-rich domain of Lsm4 function together to enhance mRNA stability and alter mRNA decay pathway dependence inSaccharomyces cerevisiae

Structure of the Dcp2–Dcp1 mRNA-decapping complex in the activated conformation

(2016) Eugene Valkov et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of the Dcp2–Dcp1 mRNA-decapping complex in the activated conformation

(2016) Eugene Valkov et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Membrane-association of mRNA decapping factors is independent of stress in budding yeast

(2016) Susanne Huch et al.   Scientific Reports

Widespread Co-translational RNA Decay Reveals Ribosome Dynamics

(2015) Vicent Pelechano et al.   CELL

Codon Optimality Is a Major Determinant of mRNA Stability

(2015) Vladimir Presnyak et al.   CELL

Pheromone-encoding mRNA is transported to the yeast mating projection by specific RNP granules

(2015) Stella Aronov et al.   JOURNAL OF CELL BIOLOGY

Control of mRNA decapping by positive and negative regulatory elements in the Dcp2 C-terminal domain

(2015) Feng He et al.   RNA

mRNA localization to Pbodies in yeast is biphasic with many mRNAs captured in a late Bfr1pdependent wave

(2014) C. E. Simpson et al.   JOURNAL OF CELL SCIENCE

Quantifying mRNA targeting to P-bodies in living human cells reveals their dual role in mRNA decay and storage

(2014) Adva Aizer et al.   JOURNAL OF CELL SCIENCE

Promoter sequences direct cytoplasmic localization and translation of mRNAs during starvation in yeast

(2014) Brian M. Zid et al.   NATURE

Pat1 contributes to the RNA binding activity of the Lsm1-7–Pat1 complex

(2014) Ashis Chowdhury et al.   RNA

Granules Harboring Translationally Active mRNAs Provide a Platform for P-Body Formation following Stress

(2014) Jennifer Lui et al.   Cell Reports

Interrelations between translation and general mRNA degradation in yeast

(2014) Susanne Huch et al.   Wiley Interdisciplinary Reviews-RNA

Cytoplasmic 5′-3′ exonuclease Xrn1p is also a genome-wide transcription factor in yeast

(2014) Daniel A. Medina et al.   Frontiers in Genetics

The P-body component USP52/PAN2 is a novel regulator ofHIF1AmRNA stability

(2013) John S. Bett et al.   BIOCHEMICAL JOURNAL

Gene Expression Is Circular: Factors for mRNA Degradation Also Foster mRNA Synthesis

(2013) Gal Haimovich et al.   CELL

Global Analysis of Eukaryotic mRNA Degradation Reveals Xrn1-Dependent Buffering of Transcript Levels

(2013) Mai Sun et al.   MOLECULAR CELL

Structural analysis of the yeast Dhh1–Pat1 complex reveals how Dhh1 engages Pat1, Edc3 and RNA in mutually exclusive interactions

(2013) Humayun Sharif et al.   NUCLEIC ACIDS RESEARCH

To the pore and through the pore: A story of mRNA export kinetics

(2012) Marlene Oeffinger et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

RNA Degradation in Saccharomyces cerevisae

(2012) Roy Parker   GENETICS

Processing Body and Stress Granule Assembly Occur by Independent and Differentially Regulated Pathways in Saccharomyces cerevisiae

(2012) K. H. Shah et al.   GENETICS

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Sequestration of Highly Expressed mRNAs in Cytoplasmic Granules, P-Bodies, and Stress Granules Enhances Cell Viability

(2012) Anna Lavut et al.   PLoS Genetics

Genome-wide studies of mRNA synthesis and degradation in eukaryotes

(2011) José E. Pérez-Ortín et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

The structural basis of Edc3- and Scd6-mediated activation of the Dcp1:Dcp2 mRNA decapping complex

(2011) Simon A Fromm et al.   EMBO JOURNAL

Reconsidering Movement of Eukaryotic mRNAs between Polysomes and P Bodies

(2011) Joshua A. Arribere et al.   MOLECULAR CELL

XUTs are a class of Xrn1-sensitive antisense regulatory non-coding RNA in yeast

(2011) E. L. van Dijk et al.   NATURE

Diauxic shift-dependent relocalization of decapping activators Dhh1 and Pat1 to polysomal complexes

(2011) Sheona P. Drummond et al.   NUCLEIC ACIDS RESEARCH

Identification and Analysis of the Interaction between Edc3 and Dcp2 in Saccharomyces cerevisiae

(2010) Y. Harigaya et al.   MOLECULAR AND CELLULAR BIOLOGY

Decapping Activators in Saccharomyces cerevisiae Act by Multiple Mechanisms

(2010) Tracy Nissan et al.   MOLECULAR CELL

A split active site couples cap recognition by Dcp2 to activation

(2010) Stephen N Floor et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Lsm1-7-Pat1 complex:  A link between 3’ and 5’-ends in mRNA decay?

(2010) Sundaresan Tharun   RNA Biology

Dcp1 links coactivators of mRNA decapping to Dcp2 by proline recognition

(2010) M. S. Borja et al.   RNA

Robust heat shock induces eIF2 -phosphorylation-independent assembly of stress granules containing eIF3 and 40S ribosomal subunits in budding yeast, Saccharomyces cerevisiae

(2009) T. Grousl et al.   JOURNAL OF CELL SCIENCE

Co-translational mRNA decay in Saccharomyces cerevisiae

(2009) Wenqian Hu et al.   NATURE

Deadenylation is prerequisite for P-body formation and mRNA decay in mammalian cells

(2008) Dinghai Zheng et al.   JOURNAL OF CELL BIOLOGY

A role for Q/N-rich aggregation-prone regions in P-body localization

(2008) M. A. M. Reijns et al.   JOURNAL OF CELL SCIENCE

The transcriptional inhibitor thiolutin blocks mRNA degradation in yeast

(2007) Vicent Pelechano et al.   YEAST