Effects of ComplementC4Gene Copy Number Variations, Size Dichotomy, andC4ADeficiency on Genetic Risk and Clinical Presentation of Systemic Lupus Erythematosus in East Asian Populations

Gene copy-number variations (CNVs) of complementC4andC4Adeficiency in genetic risk and pathogenesis of juvenile dermatomyositis

(2015) Katherine E Lintner et al.   ANNALS OF THE RHEUMATIC DISEASES

Anti-C1q antibodies in systemic lupus erythematosus

(2014) A-M Orbai et al.   LUPUS

Deletion Variants ofRABGAP1L, 10q21.3, andC4Are Associated With the Risk of Systemic Lupus Erythematosus in Korean Women

(2013) Ji-Hong Kim et al.   ARTHRITIS AND RHEUMATISM

Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner

(2013) Priyadarshini Chatterjee et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Genetically Determined Partial Complement C4 Deficiency States Are Not Independent Risk Factors for SLE in UK and Spanish Populations

(2012) Lora Boteva et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Derivation and validation of the Systemic Lupus International Collaborating Clinics classification criteria for systemic lupus erythematosus

(2012) Michelle Petri et al.   ARTHRITIS AND RHEUMATISM

Genes identified in Asian SLE GWASs are also associated with SLE in Caucasian populations

(2012) Chuan Wang et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Complement in the immunopathogenesis of rheumatic disease

(2012) Gunnar Sturfelt et al.   Nature Reviews Rheumatology

Structural basis for activation of the complement system by component C4 cleavage

(2012) R. T. Kidmose et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clinical presentations and molecular basis of complement C1r deficiency in a male African–American patient with systemic lupus erythematosus

(2011) YL Wu et al.   LUPUS

Systemic Lupus Erythematosus

(2011) George C. Tsokos   NEW ENGLAND JOURNAL OF MEDICINE

Confirmation of C4 gene copy number variation and the association with systemic lupus erythematosus in Chinese Han population

(2011) Yongmei Lv et al.   RHEUMATOLOGY INTERNATIONAL

The complex nature of serum C3 and C4 as biomarkers of lupus renal flare

(2010) DJ Birmingham et al.   LUPUS

Cutaneous manifestations of complement deficiencies

(2010) D. Lipsker et al.   LUPUS

Epidemiology and survival of systemic lupus erythematosus in Hong Kong Chinese

(2010) CC Mok   LUPUS

C1q inhibits immune complex-induced interferon-α production in plasmacytoid dendritic cells: A novel link between C1q deficiency and systemic lupus erythematosus pathogenesis

(2009) Christian Lood et al.   ARTHRITIS AND RHEUMATISM

Molecular basis of complete complement C4 deficiency in two North-African families with systemic lupus erythematosus

(2009) Y L Wu et al.   GENES AND IMMUNITY

Great genotypic and phenotypic diversities associated with copy-number variations of complement C4 and RP-C4-CYP21-TNX (RCCX) modules: A comparison of Asian-Indian and European American populations

(2009) Kapil Saxena et al.   MOLECULAR IMMUNOLOGY

Finding the missing heritability of complex diseases

(2009) Teri A. Manolio et al.   NATURE

Variation analysis and gene annotation of eight MHC haplotypes: The MHC Haplotype Project

(2008) Roger Horton et al.   IMMUNOGENETICS