期刊
ALLERGOLOGY INTERNATIONAL
卷 65, 期 4, 页码 378-387出版社
JAPANESE SOCIETY ALLERGOLOGY
DOI: 10.1016/j.alit.2016.07.002
关键词
Allergen components; Component resolved diagnosis; Diagnosis; Food allergen; Molecular allergology
资金
- Japan Agency for Medical Research and Development, AMED [15649725]
- Grants-in-Aid for Scientific Research [26282018] Funding Source: KAKEN
Due to the high prevalence of food allergic diseases globally there are increasing demands in clinical practice for managing IgE-mediated conditions. During the last decade, component resolved diagnostics has been introduced into the field of clinical allergology, providing information that cannot be obtained from extract-based tests. Component resolved data facilitate more precise diagnosis of allergic diseases and identify sensitizations attributable to cross-reactivity. Furthermore it assists risk assessment in clinical practice as sensitization to some allergenic molecules is related to persistence of clinical symptoms and systemic rather than local reactions. The information may also aid the clinician in prescription of oral immunotherapy (OIT) in patients with severe symptoms, and in giving advice on food allergen avoidance or on the need to perform food challenges. The use of allergen components is rapidly evolving and increases our possibility to treat food allergic patients with a more individual approach. Using molecular allergology, we can already now better diagnose, prognose and grade the food allergy. In summary, daily routine molecular allergy diagnostics offers a number of benefits that give us a higher diagnostic precision and allow for better management of the patient. Copyright (C) 2016, Japanese Society of Allergology. Production and hosting by Elsevier B.V. This is an open access article under the CC BY-NC-ND license.
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