2-arachidonoylglycerol signaling impairs short-term fear extinction

The paraventricular thalamus controls a central amygdala fear circuit

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Different genetic factors underlie fear conditioning and episodic memory

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2-AG promotes the expression of conditioned fear via cannabinoid receptor type 1 on GABAergic neurons

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Amygdala Inputs to the Ventral Hippocampus Bidirectionally Modulate Social Behavior

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Hippocampal Metaplasticity Is Required for the Formation of Temporal Associative Memories

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Impaired Contextual Modulation of Memories in PTSD: An fMRI and Psychophysiological Study of Extinction Retention and Fear Renewal

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Bidirectional switch of the valence associated with a hippocampal contextual memory engram

(2014) Roger L. Redondo et al.   NATURE

Tracking explicit and implicit long-lasting traces of fearful memories in humans

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Amygdala Microcircuits Controlling Learned Fear

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Multiple Mechanistically Distinct Modes of Endocannabinoid Mobilization at Central Amygdala Glutamatergic Synapses

(2014) Teniel S. Ramikie et al.   NEURON

Central anandamide deficiency predicts stress-induced anxiety: behavioral reversal through endocannabinoid augmentation

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Detection of a Temporal Error Triggers Reconsolidation of Amygdala-Dependent Memories

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Thy1-Expressing Neurons in the Basolateral Amygdala May Mediate Fear Inhibition

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Substrate-selective COX-2 inhibition decreases anxiety via endocannabinoid activation

(2013) Daniel J Hermanson et al.   NATURE NEUROSCIENCE

Experience-dependent modification of a central amygdala fear circuit

(2013) Haohong Li et al.   NATURE NEUROSCIENCE

Implications of memory modulation for post-traumatic stress and fear disorders

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From Pavlov to PTSD: The extinction of conditioned fear in rodents, humans, and anxiety disorders

(2013) Michael B. VanElzakker et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Basal variability in CREB phosphorylation predicts trait-like differences in amygdala-dependent memory

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Amygdala FAAH and anandamide: mediating protection and recovery from stress

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Highly Selective Inhibitors of Monoacylglycerol Lipase Bearing a Reactive Group that Is Bioisosteric with Endocannabinoid Substrates

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Amygdala microcircuits mediating fear expression and extinction

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Bimodal Control of Fear-Coping Strategies by CB1 Cannabinoid Receptors

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Disruption of fatty acid amide hydrolase activity prevents the effects of chronic stress on anxiety and amygdalar microstructure

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Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity

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Endocannabinoid Signaling and Synaptic Function

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Fear Extinction as a Model for Translational Neuroscience: Ten Years of Progress

(2011) Mohammed R. Milad et al.   Annual Review of Psychology

Differential Role of Anandamide and 2-Arachidonoylglycerol in Memory and Anxiety-like Responses

(2011) Arnau Busquets-Garcia et al.   BIOLOGICAL PSYCHIATRY

Molecular Mechanisms of Fear Learning and Memory

(2011) Joshua P. Johansen et al.   CELL

Sensory-Specific Associations Stored in the Lateral Amygdala Allow for Selective Alteration of Fear Memories

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The endocannabinoid system in anxiety, fear memory and habituation

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Amygdala circuitry mediating reversible and bidirectional control of anxiety

(2011) Kay M. Tye et al.   NATURE

Reversible Gating of Endocannabinoid Plasticity in the Amygdala by Chronic Stress: A Potential Role for Monoacylglycerol Lipase Inhibition in the Prevention of Stress-Induced Behavioral Adaptation

(2011) Joshua J Sumislawski et al.   NEUROPSYCHOPHARMACOLOGY

Endocannabinoid signaling in the amygdala: anatomy, synaptic signaling, behavior, and adaptations to stress

(2011) T.S. Ramikie et al.   NEUROSCIENCE

Enhancement of endocannabinoid signaling with JZL184, an inhibitor of the 2-arachidonoylglycerol hydrolyzing enzyme monoacylglycerol lipase, produces anxiolytic effects under conditions of high environmental aversiveness in rats

(2011) Natale R. Sciolino et al.   PHARMACOLOGICAL RESEARCH

Unique inhibitory synapse with particularly rich endocannabinoid signaling machinery on pyramidal neurons in basal amygdaloid nucleus

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Attention bias toward threat is associated with exaggerated fear expression and impaired extinction in PTSD

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Functional Interactions between Stress and the Endocannabinoid System: From Synaptic Signaling to Behavioral Output

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Genetic dissection of an amygdala microcircuit that gates conditioned fear

(2010) Wulf Haubensak et al.   NATURE

Inhibition of endocannabinoid catabolic enzymes elicits anxiolytic-like effects in the marble burying assay

(2010) Steven G. Kinsey et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Endogenous cannabinoid signaling is essential for stress adaptation

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Endogenous cannabinoids trigger the depolarization-induced suppression of excitation in the lateral amygdala

(2009) S. A. Kodirov et al.   LEARNING & MEMORY

Endocannabinoid-Mediated Control of Synaptic Transmission

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Association of the cannabinoid receptor gene (CNR1) with ADHD and post-traumatic stress disorder

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Adaptations in endocannabinoid signaling in response to repeated homotypic stress: a novel mechanism for stress habituation

(2008) Sachin Patel et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Facilitation of contextual fear memory extinction and anti-anxiogenic effects of AM404 and cannabidiol in conditioned rats

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Switching on and off fear by distinct neuronal circuits

(2008) Cyril Herry et al.   NATURE

Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects

(2008) Jonathan Z Long et al.   Nature Chemical Biology

Short- and long-term effects of cannabinoids on the extinction of contextual fear memory in rats

(2008) Fabrício A. Pamplona et al.   NEUROBIOLOGY OF LEARNING AND MEMORY