Uranium-induced rat kidney cell cytotoxicity is mediated by decreased endogenous hydrogen sulfide (H2S) generation involved in reduced Nrf2 levels

Dual regulation of transcription factor Nrf2 by Keap1 and by the combined actions of β-TrCP and GSK-3

(2015) John D. Hayes et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Hydrogen sulfide (H2S) attenuates uranium-induced acute nephrotoxicity through oxidative stress and inflammatory response via Nrf2-NF-κB pathways

(2015) Jifang Zheng et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Structural and functional characterization of Nrf2 degradation by glycogen synthase kinase 3/β-TrCP

(2015) Antonio Cuadrado   FREE RADICAL BIOLOGY AND MEDICINE

Alcohol Causes Alveolar Epithelial Oxidative Stress by Inhibiting the Nuclear Factor (Erythroid-Derived 2)–Like 2–Antioxidant Response Element Signaling Pathway

(2013) J. Spencer Jensen et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Polysulfide exerts a protective effect against cytotoxicity caused byt-buthylhydroperoxide through Nrf2 signaling in neuroblastoma cells

(2013) Shin Koike et al.   FEBS LETTERS

Hydrogen Sulfide Is a Signaling Molecule and a Cytoprotectant

(2012) Hideo Kimura et al.   ANTIOXIDANTS & REDOX SIGNALING

Hydrogen Sulfide Protects Against Cellular Senescence via S-Sulfhydration of Keap1 and Activation of Nrf2

(2012) Guangdong Yang et al.   ANTIOXIDANTS & REDOX SIGNALING

The Gasotransmitter Hydrogen Sulfide Induces Nrf2-Target Genes by Inactivating the Keap1 Ubiquitin Ligase Substrate Adaptor Through Formation of a Disulfide Bond Between Cys-226 and Cys-613

(2012) John M. Hourihan et al.   ANTIOXIDANTS & REDOX SIGNALING

Effect of endogenous hydrogen sulfide inhibition on structural and functional renal disturbances induced by gentamicin

(2012) H.D.C. Francescato et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Are antioxidant and transcriptional responses useful for discriminating between chemo- and radiotoxicity of uranium in the crayfish Procambarus clarkii?

(2012) Simone Al Kaddissi et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Hydrogen Sulfide and Cell Signaling

(2011) Ling Li et al.   Annual Review of Pharmacology and Toxicology

Hydrogen Sulfide Ameliorates Tobacco Smoke-Induced Oxidative Stress and Emphysema in Mice

(2011) Weihong Han et al.   ANTIOXIDANTS & REDOX SIGNALING

Downregulation of the renal and hepatic hydrogen sulfide (H2S)-producing enzymes and capacity in chronic kidney disease

(2011) M. A. Aminzadeh et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Hydrogen sulfide: its production, release and functions

(2010) Hideo Kimura   AMINO ACIDS

Redox Biochemistry of Hydrogen Sulfide

(2010) Omer Kabil et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Renal Effects of Exposure to Natural and Depleted Uranium: A Review of the Epidemiologic and Experimental Data

(2010) Xabier Arzuaga et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS

Inhibition of hydrogen sulphide formation reduces cisplatin-induced renal damage

(2010) H. D. C. Francescato et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Nephrotoxicity of Uranium: Pathophysiological, Diagnostic and Therapeutic Perspectives

(2010) Laura Vicente-Vicente et al.   TOXICOLOGICAL SCIENCES

Nrf2 and NF-κB and Their Concerted Modulation in Cancer Pathogenesis and Progression

(2010) Ilaria Bellezza et al.   Cancers

Novel Insights Into Hydrogen Sulfide–Mediated Cytoprotection

(2009) John W. Calvert et al.   ANTIOXIDANTS & REDOX SIGNALING

Hydrogen Sulfide Increases Glutathione Production and Suppresses Oxidative Stress in Mitochondria

(2009) Yuka Kimura et al.   ANTIOXIDANTS & REDOX SIGNALING

Hydrogen Sulfide Mediates Cardioprotection Through Nrf2 Signaling

(2009) John W. Calvert et al.   CIRCULATION RESEARCH

ACUTE CHEMICAL TOXICITY OF URANIUM

(2009) Ronald L. Kathren et al.   HEALTH PHYSICS

Production and Actions of Hydrogen Sulfide, a Novel Gaseous Bioactive Substance, in the Kidneys

(2009) M. Xia et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Hydrogen sulfide is an endogenous stimulator of angiogenesis

(2009) A. Papapetropoulos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcription factor Nrf2 mediates an adaptive response to sulforaphane that protects fibroblasts in vitro against the cytotoxic effects of electrophiles, peroxides and redox-cycling agents

(2009) Larry G. Higgins et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

H2S Protects Against Methionine–Induced Oxidative Stress in Brain Endothelial Cells

(2008) Neetu Tyagi et al.   ANTIOXIDANTS & REDOX SIGNALING

Keap1/Nrf2 Signaling Regulates Oxidative Stress Tolerance and Lifespan in Drosophila

(2008) Gerasimos P. Sykiotis et al.   DEVELOPMENTAL CELL

Arsenic-induced malignant transformation of human keratinocytes: Involvement of Nrf2

(2008) Jingbo Pi et al.   FREE RADICAL BIOLOGY AND MEDICINE

Hydrogen sulfide protects astrocytes against H2O2-induced neural injury via enhancing glutamate uptake

(2008) Ming Lu et al.   FREE RADICAL BIOLOGY AND MEDICINE