Nanoparticle Delivered Human Biliverdin Reductase-Based Peptide Increases Glucose Uptake by Activating IRK/Akt/GSK3 Axis: The Peptide Is Effective in the Cell and Wild-Type and Diabetic Ob/Ob Mice

Neuroprotective effect of hemeoxygenase-1/glycogen synthase kinase-3β modulators in 3-nitropropionic acid-induced neurotoxicity in rats

(2015) A. Khan et al.   NEUROSCIENCE

Human biliverdin reductase-based peptides activate and inhibit glucose uptake through direct interaction with the kinase domain of insulin receptor

(2014) Peter E. M. Gibbs et al.   FASEB JOURNAL

Nuclear Heme Oxygenase-1 (HO-1) Modulates Subcellular Distribution and Activation of Nrf2, Impacting Metabolic and Anti-oxidant Defenses

(2014) Chhanda Biswas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Atypical NF- B-Regulated Pathway Mediates Phorbol Ester-Dependent Heme Oxygenase-1 Gene Activation in Monocytes

(2014) S. Naidu et al.   JOURNAL OF IMMUNOLOGY

Nanoparticle Adhesion to the Cell Membrane and Its Effect on Nanoparticle Uptake Efficiency

(2013) Anna Lesniak et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Human Biliverdin Reductase-based Peptide Fragments and Biliverdin Regulate Protein Kinase Cδ Activity

(2012) Tihomir Miralem et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PI3K-PKB/Akt Pathway

(2012) B. A. Hemmings et al.   Cold Spring Harbor Perspectives in Biology

The Role of Bilirubin in Diabetes, Metabolic Syndrome, and Cardiovascular Diseases

(2012) Libor Vítek   Frontiers in Pharmacology

Predominant role of obesity/insulin resistance in oxidative stress development

(2011) Massimo D’Archivio et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Protective role of heme oxygenase-1 against inflammation in atherosclerosis

(2011) William Durante   Frontiers in Bioscience-Landmark

Formation of Ternary Complex of Human Biliverdin Reductase-Protein Kinase Cδ-ERK2 Protein Is Essential for ERK2-mediated Activation of Elk1 Protein, Nuclear Factor-κB, and Inducible Nitric-oxidase Synthase (iNOS)

(2011) Peter E. M. Gibbs et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nanoparticle delivery of a peptide targeting EGFR signaling

(2011) Sang Kyoon Kim et al.   JOURNAL OF CONTROLLED RELEASE

Signaling to heme oxygenase-1 and its anti-inflammatory therapeutic potential

(2010) Ananta Paine et al.   BIOCHEMICAL PHARMACOLOGY

The coordinated increased expression of biliverdin reductase and heme oxygenase-2 promotes cardiomyocyte survival: a reductase-based peptide counters β-adrenergic receptor ligand-mediated cardiac dysfunction

(2010) Bo Ding et al.   FASEB JOURNAL

Silencing Glycogen Synthase Kinase-3β Inhibits Acetaminophen Hepatotoxicity and Attenuates JNK Activation and Loss of Glutamate Cysteine Ligase and Myeloid Cell Leukemia Sequence 1

(2010) Mie Shinohara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glycogen synthase kinase 3: more than a namesake

(2009) Geetha Vani Rayasam et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cell Surface Biliverdin Reductase Mediates Biliverdin-induced Anti-inflammatory Effects via Phosphatidylinositol 3-Kinase and Akt

(2009) Barbara Wegiel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of the S-denitrosylating activity of bilirubin

(2009) Eugenio Barone et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Heme oxygenase-1: from biology to therapeutic potential

(2009) Miguel P. Soares et al.   TRENDS IN MOLECULAR MEDICINE

A GSK-3/TSC2/mTOR pathway regulates glucose uptake and GLUT1 glucose transporter expression

(2008) Carolyn L. Buller et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Biliverdin reductase is a transporter of haem into the nucleus and is essential for regulation ofHO-1gene expression by haematin

(2008) Cicerone Tudor et al.   BIOCHEMICAL JOURNAL

Alterations of insulin signaling in type 2 diabetes: A review of the current evidence from humans

(2008) Sara Fröjdö et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Discovering and improving novel peptide therapeutics

(2008) D MCGREGOR   CURRENT OPINION IN PHARMACOLOGY

Selective Regulation of Heme Oxygenase-1 Expression and Function by Insulin through IRS1/Phosphoinositide 3-Kinase/Akt-2 Pathway

(2008) Pedro Geraldes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pharmacological and Clinical Aspects of Heme Oxygenase

(2008) N. G. Abraham et al.   PHARMACOLOGICAL REVIEWS

Human biliverdin reductase is an ERK activator; hBVR is an ERK nuclear transporter and is required for MAPK signaling

(2008) N. Lerner-Marmarosh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA