Review
Immunology
Si-yue Zhai, Michael G. Kong, Yu-min Xia
Summary: Skin diseases can be categorized into infectious diseases, non-infectious inflammatory diseases, cancers, and wounds. The underlying causes include microbial infections, autoimmune responses, abnormal cellular proliferation or differentiation, and excessive production of inflammatory factors. Cold atmospheric plasma (CAP), as an innovative and non-invasive therapeutic approach, has shown promising efficacy in dermatology by inhibiting infections, promoting wound healing, suppressing cancer growth, and improving psoriasis or vitiligo lesions. This review summarizes recent advances in CAP therapies for various skin diseases and proposes future strategies for increasing effectiveness and expanding clinical indications.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Agronomy
Xiaoguang Lu, Yuhan Wu, Chaoyue Tang, Chang Liu, Ninghui Li, Yuchen Du, Lianshuang Fu, Xin Liu, Jun Liu, Xiaonan Wang
Summary: Recent findings suggest that cold acclimation can enhance cold resistance in wheat. This study elucidated the potential mechanisms of cold acclimation in the winter wheat variety DM1 and the variety CS, focusing on the role of the antioxidant system. The results showed that DM1 exhibited a higher cold tolerance than CS by increasing the expression of POD genes, LEA, CAP, and cold-responsive proteins.
Article
Plant Sciences
Sun-Hyung Lim, Da-Hye Kim, Jae-A. Jung, Jong-Yeol Lee
Summary: The study found that the alternative splicing of CmbHLH2 plays a key role in regulating the color changes of chrysanthemum ray florets. The shorter splicing variant CmbHLH2(Short) failed to activate anthocyanin biosynthetic genes and induce pigment accumulation, while the full-length form CmbHLH2(Full) promoted these processes when co-expressed with CmMYB6.
FRONTIERS IN PLANT SCIENCE
(2021)
Article
Forestry
Yan-Min Wang, Yi-Ming Zhang, Xin Zhang, Xin Zhao, Yu Zhang, Chao Wang, Yu-Cheng Wang, Liu-Qiang Wang
Summary: PsnICE1 is a key gene in Xiaohei poplar that plays a positive role in cold tolerance by regulating the expression of cold stress-responsive genes. Its overexpression enhances tolerance to cold stress, while silencing of PsnICE1 results in reduced cold tolerance. PsnICE1 binds to specific elements to regulate stress-related genes involved in ROS scavenging, making it a potential candidate for improving plant cold tolerance through molecular breeding.
Article
Horticulture
Huili Sun, Yali Hou, Yimeng Mei, Peng Hao, Xiaoqian Wang, Deguo Lyu
Summary: The study demonstrates that 5-aminolevulinic acid (ALA) improves photooxidative stress tolerance in pear leaves by modulating NADPH oxidase-mediated H2O2 signaling pathways. Exogenous ALA alleviates chlorophyll content and photosystem II efficiency decreases, reduces oxidative damage, and enhances antioxidative enzyme activities. Additionally, ALA-induced tolerance is dependent on RBOH-mediated H2O2 production.
SCIENTIA HORTICULTURAE
(2022)
Article
Plant Sciences
Dandan Li, Jingli Yang, Solme Pak, Minzhen Zeng, Jiali Sun, Sen Yu, Yuting He, Chenghao Li
Summary: A novel regulatory pathway for drought tolerance in Populus ussuriensis roots was discovered, where PuC3H35 mediated proanthocyanidin and lignin biosynthesis by collaboratively regulating various gene modules. This pathway enhances plant adaptation to drought stress by promoting antioxidant activity and mechanical support.
Review
Biochemistry & Molecular Biology
Yaqi Hao, Xiumei Zong, Pan Ren, Yuqi Qian, Aigen Fu
Summary: The bHLH transcription factor family in plants is involved in regulating various physiological processes such as biosynthesis, metabolism, and plant hormone signaling by forming dimers. They play important roles in plant growth and development, stress responses, and signaling networks.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Entomology
Jie Zhang, Mengyao Zhu, Qilin Li, Ting Tang, Liang Wen, Jielai Zhong, Ruonan Zhang, Xiao-Qiang Yu, Yuzhen Lu
Summary: bHLH transcription factors play crucial roles in various metabolic and developmental processes in eukaryotes, and this study investigated their response to different pathogens in the polyphagous insect, Spodoptera litura. The research identified a new bHLH gene specific to Lepidoptera, analyzed the expression profiles of bHLH genes in response to pathogens, and highlighted the downregulation of SlbHLHs in the midgut of S. litura larvae after Bacillus thuringiensis treatment. These findings provide insights into the host-pathogen interaction mechanism mediated by bHLH members.
Article
Microbiology
Vineet Dubey, Rinki Gupta, Ranjana Pathania
Summary: In the study, it was found that treatment with the last-resort antibiotic polymyxin B caused continuous variations in tolerance among different clinical isolates of Acinetobacter baumannii. The activity of superoxide dismutase (sodB) was identified as a major contributor to the tolerance of A. baumannii to polymyxin B. Rifampicin was effective in eradicating polymyxin B-induced A. baumannii persisters by increasing the generation of reactive oxygen species (ROS), which was linked to significant downregulation of sodB. The combination of polymyxin B and rifampicin was proposed as an effective antipersister strategy in clearing polymyxin B-induced A. baumannii persisters.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
(2021)
Article
Biochemistry & Molecular Biology
Junjian Li, Siyi Chen, Yaxin Yin, Qiaobo Shan, Chunfang Zheng, Yan Chen
Summary: This study comprehensively analyzed the bHLH family in Kandelia obovata and identified several members associated with photoinhibition under cold or drought stress. These findings may be helpful for further enhancing cold and drought tolerance and molecular breeding in K. obovata through genetic engineering.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Zhuo Huang, Si-Han Jin, Li Yang, Li Song, Yuan-Hong Wang, Lin-Li Jian, Cai-Zhong Jiang
Summary: The study isolated a dehydration-inducible bHLH transcription factor gene MfbHLH145 from M. flabellifolia, which enhanced drought and salt tolerance in Arabidopsis. MfbHLH145 contributes to enhanced leaf water retention capacity through the promotion of stomatal closure, increased osmolyte accumulation, and increased antioxidant enzyme activities.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Chunmei Yu, Ming Yan, Huizhen Dong, Jie Luo, Yongchao Ke, Anfang Guo, Yanhong Chen, Jian Zhang, Xiaosan Huang
Summary: By studying the ZmbHLH55 transcription factor in maize, researchers have uncovered a novel regulatory mechanism for Ascorbic acid (AsA) biosynthesis, potentially enhancing plant salt stress tolerance. Through controlling the expression of several related genes, ZmbHLH55 can affect AsA levels, thereby influencing plant growth and antioxidant capabilities under salt stress conditions.
Review
Plant Sciences
Jagadish Rane, Ajay Kumar Singh, Manish Tiwari, P. V. Vara Prasad, S. V. Krishna Jagadish
Summary: This review focuses on the role of the balance between reactive oxygen species (ROS) production and antioxidative system (AOS) in enhancing effective water use by crops under water-limited dryland conditions. Manipulating this balance through genetic improvement and exogenous compounds application can provide practical solutions for improving crop productivity in water-limited dryland environments.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Plant Sciences
Jong-Min Lim, Sokyong Jung, Jae-Sun In, Youn-Il Park, Won-Joong Jeong
Summary: Temperature is crucial for regulating growth in algae. Temperature stress can lead to oxidative damage in algae, but enhancing oxidative stress resistance through alcohol metabolism could improve tolerance.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Plant Sciences
Qi Wang, Haifan Shi, Risheng Huang, Rong Ye, Yurong Luo, Zhenfei Guo, Shaoyun Lu
Summary: The study revealed that MfAIR12 is induced under low temperature conditions and can increase the accumulation of H2O2 in the apoplast, thus enhancing the plant's cold resistance. Arabidopsis mutant air12 showed decreased cold tolerance, which could be restored by expressing MfAIR12.
PLANT CELL AND ENVIRONMENT
(2021)
Article
Biotechnology & Applied Microbiology
Xueying Liu, Zhe Liu, Ziwei Hao, Guodong Chen, Kaijie Qi, Hao Zhang, Huijun Jiao, Xiao Wu, Shaoling Zhang, Juyou Wu, Peng Wang
Article
Plant Sciences
Xin Gong, Zhihua Xie, Kaijie Qi, Liangyi Zhao, Yazhou Yuan, Jiahui Xu, Weikang Rui, Katsuhiro Shiratake, Jianping Bao, Shahrokh Khanizadeh, Shaoling Zhang, Shutian Tao
HORTICULTURE RESEARCH
(2020)
Article
Plant Sciences
Liying Qi, Ling Chen, Chuansen Wang, Shaoling Zhang, Yingjie Yang, Jianlong Liu, Dingli Li, Jiankun Song, Ran Wang
Article
Plant Sciences
Xin Gong, Jianping Bao, Jing Chen, Kaijie Qi, Zhihua Xie, Weikang Rui, Guowei Hao, Katsuhiro Shiratake, Shahrokh Khanizadeh, Shaoling Zhang, Shutian Tao
ACTA PHYSIOLOGIAE PLANTARUM
(2020)
Article
Environmental Sciences
Jiyu Li, Lu Zheng, Ye Fan, Yuerong Wang, Yurou Ma, Dongfang Gu, Yaping Lu, Shaoling Zhang, Xi Chen, Wei Zhang
Summary: PbMTP8.1 is a specific manganese transporter localized to the pre-vacuolar compartment, which enhances plant tolerance to manganese by sequestering manganese into vacuoles.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Article
Biochemistry & Molecular Biology
Fatemeh Rasouli, Ali Kiani-Pouya, Lana Shabala, Leiting Li, Ayesha Tahir, Min Yu, Rainer Hedrich, Zhonghua Chen, Richard Wilson, Heng Zhang, Sergey Shabala
Summary: The halophyte quinoa responds to salinity stress by altering the protein composition of guard cells, with differential expression of proteins involved in signaling pathways and stress responses. Upregulated proteins in response to salt treatment include those related to ABA signaling and sucrose-starch metabolism, while high levels of aspartic proteinase are associated with mitigating oxidative stress induced by saline conditions.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Biochemistry & Molecular Biology
Chao Gu, Ruo-Fan Wu, Cai-Yun Yu, Kai-Jie Qi, Chen Wu, Hu-Ping Zhang, Shao-Ling Zhang
Summary: Sorbitol accumulation in pear fruit is cooperatively mediated by various SOTs, including SOT3, SOT6/20, SOT19/21, and SOT22. Sorbitol concentration showed positive correlations to fructose and glucose concentrations, indicating its role in determining fruit sweetness.
Article
Cell Biology
Shaobo Zhu, Jinge Gu, Juanjuan Yao, Yichen Li, Zheting Zhang, Wencheng Xia, Zhen Wang, Xinrui Gui, Leiting Li, Dan Li, Heng Zhang, Cong Liu
Summary: This study demonstrates the role of protein liquid-liquid phase separation (LLPS) in the heat stress response in plants by discovering the LLPS of two RNA-binding proteins, RBGD2 and RBGD4. The findings suggest that manipulation of protein LLPS could be a strategy to improve plant stress resistance.
DEVELOPMENTAL CELL
(2022)
Article
Plant Sciences
Leiting Li, Meng Li, Juyou Wu, Hao Yin, Jim M. Dunwell, Shaoling Zhang
Summary: This study identified key sorbitol metabolism-related genes in Rosaceae species and found that the sorbitol pathway genes were expanded through dispersed and tandem gene duplications in the sorbitol present group (SPG). The sorbitol dehydrogenase (SDH) and sorbitol-6-phosphate dehydrogenase (S6PDH) clade A were under stronger purifying selection in SPG, while the sorbitol transporter (SOT) genes were under positive selection in SPG.
Article
Plant Sciences
Wei Jiang, Chao Li, Leiting Li, Yali Li, Zhihao Wang, Feiyu Yu, Feng Yi, Jianhan Zhang, Jian-Kang Zhu, Heng Zhang, Yan Li, Chunzhao Zhao
Summary: This study characterizes CqCrRLK1L and CqRALF family genes in quinoa and provides evidence to support their roles in salt stress response.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Plant Sciences
Meng-Fan Qin, Lei-Ting Li, Jugpreet Singh, Man-Yi Sun, Bing Bai, Si-Wei Li, Jiang-Ping Ni, Jia-Ying Zhang, Xun Zhang, Wei-Lin Wei, Ming-Yue Zhang, Jia-Ming Li, Kai-Jie Qi, Shao-Ling Zhang, Awais Khan, Jun Wu
Summary: This study sequenced the genome of pear cultivars and constructed a high-density genetic map to identify genetic markers associated with fruit quality. Multiple QTLs and candidate genes related to fruit quality traits were identified, and the function of one candidate gene was confirmed through experimental transformation.
HORTICULTURE RESEARCH
(2022)
Article
Multidisciplinary Sciences
Stephen M. Richards, Leiting Li, James Breen, Nelli Hovhannisyan, Oscar Estrada, Boris Gasparyan, Matthew Gilliham, Alexia Smith, Alan Cooper, Heng Zhang
Summary: The study of well-preserved millet grains from the archaeological cave site Areni-1 in Southern Armenia reveals that DNA from these grains can be preserved for at least 1000 years, serving as a genetic resource for studying the domestication history of this cereal crop.
SCIENTIFIC REPORTS
(2022)
Article
Plant Sciences
Fatemeh Rasouli, Ali Kiani-Pouya, Ali Movahedi, Yuan Wang, Leiting Li, Min Yu, Mohammad Pourkheirandish, Meixue Zhou, Zhonghua Chen, Heng Zhang, Sergey Shabala
Summary: A comparative investigation was conducted to evaluate transcriptional changes in guard cells (GCs) of halophytic (Chenopodium quinoa) and glycophytic (Spinacia oleracea) species under salt stress. Salt-responsive genes in both species were mainly related to protein metabolism, secondary metabolites, signal transduction, and transport systems. Quinoa exhibited strong induction of genes related to abscisic acid signaling and biosynthesis, as well as transporters for amino acids, proline, sugars, sucrose, and potassium. Additionally, changes in cell wall-related genes and stomatal development were observed, suggesting that these variations may contribute to the higher salt tolerance and water use efficiency in quinoa.
PLANT AND CELL PHYSIOLOGY
(2023)
Article
Plant Sciences
Ali Kiani-Pouya, Leiting Li, Fatemeh Rasouli, Zheting Zhang, Jiahong Chen, Min Yu, Ayesha Tahir, Rainer Hedrich, Sergey Shabala, Heng Zhang
Summary: This study characterized the transcriptome differences between intact and EBC-free quinoa leaves in response to salt stress. EBC-free leaves retained most of the transcriptome responses to salt stress, but failed to induce certain specific processes such as increased DNA replication activity. These results reveal the critical role of EBCs in salt stress acclimation of quinoa leaves.
Article
Plant Sciences
Xiao Wu, Yangyang Chen, Xinjie Shi, Kaijie Qi, Peng Cao, Xueying Liu, Hao Yin, Shaoling Zhang
FUNCTIONAL PLANT BIOLOGY
(2020)