Unnatural amino acid photo-crosslinking of the IKs channel complex demonstrates a KCNE1:KCNQ1 stoichiometry of up to 4:4

Microscopic mechanisms for long QT syndrome type 1 revealed by single-channel analysis of IKs with S3 domain mutations in KCNQ1

(2015) Jodene Eldstrom et al.   HEART RHYTHM

The KCNQ1 channel - remarkable flexibility in gating allows for functional versatility

(2015) Sara I. Liin et al.   JOURNAL OF PHYSIOLOGY-LONDON

Photoinactivation of Glutamate Receptors by Genetically Encoded Unnatural Amino Acids

(2014) Viktoria Klippenstein et al.   JOURNAL OF NEUROSCIENCE

Individual IKs channels at the surface of mammalian cells contain two KCNE1 accessory subunits

(2014) L. D. Plant et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

KCNE1 divides the voltage sensor movement in KCNQ1/KCNE1 channels into two steps

(2014) Rene Barro-Soria et al.   Nature Communications

Domain–domain interactions determine the gating, permeation, pharmacology, and subunit modulation of the IKs ion channel

(2014) Mark A Zaydman et al.   eLife

[Ca2+]iElevation and Oxidative Stress Induce KCNQ1 Protein Translocation from the Cytosol to the Cell Surface and Increase Slow Delayed Rectifier (IKs) in Cardiac Myocytes

(2013) Yuhong Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IKs channels open slowly because KCNE1 accessory subunits slow the movement of S4 voltage sensors in KCNQ1 pore-forming subunits

(2013) K. J. Ruscic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-channel basis for the slow activation of the repolarizing cardiac potassium current,IKs

(2013) Daniel Werry et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamic subunit stoichiometry confers a progressive continuum of pharmacological sensitivity by KCNQ potassium channels

(2013) H. Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis of Slow Activation Gating in the Cardiac IKs Channel Complex

(2011) Nathalie Strutz-Seebohm et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Working model for the structural basis for KCNE1 modulation of the KCNQ1 potassium channel

(2011) Wade D Van Horn et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

The voltage-gated channel accessory protein KCNE2: multiple ion channel partners, multiple ways to long QT syndrome

(2011) Jodene Eldstrom et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Biophysical properties of slow potassium channels in human embryonic stem cell derived cardiomyocytes implicate subunit stoichiometry

(2011) Kai Wang et al.   JOURNAL OF PHYSIOLOGY-LONDON

Analysis of the interactions between the C-terminal cytoplasmic domains of KCNQ1 and KCNE1 channel subunits

(2010) Renjian Zheng et al.   BIOCHEMICAL JOURNAL

Beyond the Canonical 20 Amino Acids: Expanding the Genetic Lexicon

(2010) Travis S. Young et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

KCNE1 alters the voltage sensor movements necessary to open the KCNQ1 channel gate

(2010) J. D. Osteen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stoichiometry of the KCNQ1 - KCNE1 ion channel complex

(2010) K. Nakajo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The cardiac IKs channel, complex indeed

(2010) J. D. Osteen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamic Partnership between KCNQ1 and KCNE1 and Influence on Cardiac IKsCurrent Amplitude by KCNE2

(2009) Min Jiang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of KCNE1 and Implications for How It Modulates the KCNQ1 Potassium Channel†‡

(2008) Congbao Kang et al.   BIOCHEMISTRY

KCNE4 can co-associate with the IKs (KCNQ1-KCNE1) channel complex

(2008) Lauren J. Manderfield et al.   FEBS Journal

Modulation of potassium channel function confers a hyperproliferative invasive phenotype on embryonic stem cells

(2008) J. Morokuma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Counting membrane-embedded KCNE  -subunits in functioning K+ channel complexes

(2008) T. J. Morin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA