Targeting mutant RAS in patient-derived colorectal cancer organoids by combinatorial drug screening
出版年份 2016 全文链接
标题
Targeting mutant RAS in patient-derived colorectal cancer organoids by combinatorial drug screening
作者
关键词
-
出版物
eLife
Volume 5, Issue -, Pages -
出版商
eLife Sciences Organisation, Ltd.
发表日期
2016-11-15
DOI
10.7554/elife.18489
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Long-Term Culture of Genome-Stable Bipotent Stem Cells from Adult Human Liver
- (2015) Meritxell Huch et al. CELL
- Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients
- (2015) Marc van de Wetering et al. CELL
- Organoid Models of Human and Mouse Ductal Pancreatic Cancer
- (2015) Sylvia F. Boj et al. CELL
- Risk of grade 3-4 diarrhea and mucositis in colorectal cancer patients receiving anti-EGFR monoclonal antibodies regimens: A meta-analysis of 18 randomized controlled clinical trials
- (2015) Marco Miroddi et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- In Vitro Expansion of Human Gastric Epithelial Stem Cells and Their Responses to Bacterial Infection
- (2015) Sina Bartfeld et al. GASTROENTEROLOGY
- Combined BRAF and MEK Inhibition With Dabrafenib and Trametinib in BRAF V600–Mutant Colorectal Cancer
- (2015) Ryan B. Corcoran et al. JOURNAL OF CLINICAL ONCOLOGY
- Sequential cancer mutations in cultured human intestinal stem cells
- (2015) Jarno Drost et al. NATURE
- The consensus molecular subtypes of colorectal cancer
- (2015) Justin Guinney et al. NATURE MEDICINE
- Translational value of mouse models in oncology drug development
- (2015) Stephen E Gould et al. NATURE MEDICINE
- Vertical suppression of the EGFR pathway prevents onset of resistance in colorectal cancers
- (2015) Sandra Misale et al. Nature Communications
- The BCL2 Family: Key Mediators of the Apoptotic Response to Targeted Anticancer Therapeutics
- (2015) A. N. Hata et al. Cancer Discovery
- Dragging Ras Back in the Ring
- (2014) Andrew G. Stephen et al. CANCER CELL
- Failure to Induce Apoptosis via BCL-2 Family Proteins Underlies Lack of Efficacy of Combined MEK and PI3K Inhibitors for KRAS-Mutant Lung Cancers
- (2014) A. N. Hata et al. CANCER RESEARCH
- Organoid Cultures Derived from Patients with Advanced Prostate Cancer
- (2014) Dong Gao et al. CELL
- Identification of Multipotent Luminal Progenitor Cells in Human Prostate Organoid Cultures
- (2014) Wouter R. Karthaus et al. CELL
- Organoid cultures for the analysis of cancer phenotypes
- (2014) Norman Sachs et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Drugging the undruggable RAS: Mission Possible?
- (2014) Adrienne D. Cox et al. NATURE REVIEWS DRUG DISCOVERY
- Intrinsic Resistance to MEK Inhibition in KRAS Mutant Lung and Colon Cancer through Transcriptional Induction of ERBB3
- (2014) Chong Sun et al. Cell Reports
- Biased competition between Lgr5 intestinal stem cells driven by oncogenic mutation induces clonal expansion
- (2013) Hugo J. Snippert et al. EMBO REPORTS
- Bcl-2/Bcl-xL Inhibition Increases the Efficacy of MEK Inhibition Alone and in Combination with PI3 Kinase Inhibition in Lung and Pancreatic Tumor Models
- (2013) N. Tan et al. MOLECULAR CANCER THERAPEUTICS
- A bright monomeric green fluorescent protein derived from Branchiostoma lanceolatum
- (2013) Nathan C Shaner et al. NATURE METHODS
- Ex vivo culture of human prostate tissue and drug development
- (2013) Margaret M. Centenera et al. Nature Reviews Urology
- Synthetic Lethal Interaction of Combined BCL-XL and MEK Inhibition Promotes Tumor Regressions in KRAS Mutant Cancer Models
- (2012) Ryan B. Corcoran et al. CANCER CELL
- The Clinical Effect of the Dual-Targeting Strategy Involving PI3K/AKT/mTOR and RAS/MEK/ERK Pathways in Patients with Advanced Cancer
- (2012) T. Shimizu et al. CLINICAL CANCER RESEARCH
- Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling
- (2012) Vivian W. Y. Wong et al. NATURE CELL BIOLOGY
- Patient-derived tumour xenografts as models for oncology drug development
- (2012) John J. Tentler et al. Nature Reviews Clinical Oncology
- Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium
- (2011) Toshiro Sato et al. GASTROENTEROLOGY
- Patient-derived human tumour tissue xenografts in immunodeficient mice: a systematic review
- (2010) Ketao Jin et al. Clinical & Translational Oncology
- Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma
- (2010) Gideon Bollag et al. NATURE
- Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
- (2009) Toshiro Sato et al. NATURE
- Wild-TypeBRAFIs Required for Response to Panitumumab or Cetuximab in Metastatic Colorectal Cancer
- (2008) Federica Di Nicolantonio et al. JOURNAL OF CLINICAL ONCOLOGY
- Wild-TypeKRASIs Required for Panitumumab Efficacy in Patients With Metastatic Colorectal Cancer
- (2008) Rafael G. Amado et al. JOURNAL OF CLINICAL ONCOLOGY
- K-rasMutations and Benefit from Cetuximab in Advanced Colorectal Cancer
- (2008) Christos S. Karapetis et al. NEW ENGLAND JOURNAL OF MEDICINE
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