A conserved quality-control pathway that mediates degradation of unassembled ribosomal proteins

HUWE1 interacts with PCNA to alleviate replication stress

(2016) Katherine N Choe et al.   EMBO REPORTS

Ribosomal proteins produced in excess are degraded by the ubiquitin–proteasome system

(2016) Min-Kyung Sung et al.   MOLECULAR BIOLOGY OF THE CELL

ETD Outperforms CID and HCD in the Analysis of the Ubiquitylated Proteome

(2015) Tanya R. Porras-Yakushi et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Coordinated Ribosomal L4 Protein Assembly into the Pre-Ribosome Is Regulated by Its Eukaryote-Specific Extension

(2015) Philipp Stelter et al.   MOLECULAR CELL

Proteotoxic crisis, the ubiquitin-proteasome system, and cancer therapy

(2014) Raymond J Deshaies   BMC BIOLOGY

Autophagic Clearance of PolyQ Proteins Mediated by Ubiquitin-Atg8 Adaptors of the Conserved CUET Protein Family

(2014) Kefeng Lu et al.   CELL

Tumor cell-specific inhibition of MYC function using small molecule inhibitors of the HUWE1 ubiquitin ligase

(2014) S. Peter et al.   EMBO Molecular Medicine

Recent advances in defining the ubiquitylome

(2014) Tanya R Porras-Yakushi et al.   Expert Review of Proteomics

Quantitative Lys-ϵ-Gly-Gly (diGly) Proteomics Coupled with Inducible RNAi Reveals Ubiquitin-mediated Proteolysis of DNA Damage-inducible Transcript 4 (DDIT4) by the E3 Ligase HUWE1

(2014) Joel W. Thompson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Convergence of Ubiquitylation and Phosphorylation Signaling in Rapamycin-treated Yeast Cells

(2014) Vytautas Iesmantavicius et al.   MOLECULAR & CELLULAR PROTEOMICS

Quantitative proteomic analysis reveals posttranslational responses to aneuploidy in yeast

(2014) Noah Dephoure et al.   eLife

Cand1 Promotes Assembly of New SCF Complexes through Dynamic Exchange of F Box Proteins

(2013) Nathan W. Pierce et al.   CELL

Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization

(2013) Shireen A. Sarraf et al.   NATURE

Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation

(2013) Danielle L Swaney et al.   NATURE METHODS

Large-scale identification of ubiquitination sites by mass spectrometry

(2013) Namrata D Udeshi et al.   Nature Protocols

Cdc48-associated complex bound to 60S particles is required for the clearance of aberrant translation products

(2013) Q. Defenouillere et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An expanded tool kit for the auxin-inducible degron system in budding yeast

(2013) Magdalena Morawska et al.   YEAST

Cdc48/p97 promotes degradation of aberrant nascent polypeptides bound to the ribosome

(2013) Rati Verma et al.   eLife

A Ribosome-Bound Quality Control Complex Triggers Degradation of Nascent Peptides and Signals Translation Stress

(2012) Onn Brandman et al.   CELL

Pivotal Advance: Protein synthesis modulates responsiveness of differentiating and malignant plasma cells to proteasome inhibitors

(2012) Simone Cenci et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Comparative Proteomic Analysis of Eleven Common Cell Lines Reveals Ubiquitous but Varying Expression of Most Proteins

(2012) Tamar Geiger et al.   MOLECULAR & CELLULAR PROTEOMICS

Refined Preparation and Use of Anti-diglycine Remnant (K-ε-GG) Antibody Enables Routine Quantification of 10,000s of Ubiquitination Sites in Single Proteomics Experiments

(2012) Namrata D. Udeshi et al.   MOLECULAR & CELLULAR PROTEOMICS

Saccharomyces cerevisiae Ribosomal Protein L26 Is Not Essential for Ribosome Assembly and Function

(2012) R. Babiano et al.   MOLECULAR AND CELLULAR BIOLOGY

Hect E3 ubiquitin ligase Tom1 controls Dia2 degradation during the cell cycle

(2012) Dong-Hwan Kim et al.   MOLECULAR BIOLOGY OF THE CELL

Ribosomal protein S14 unties the MDM2–p53 loop upon ribosomal stress

(2012) X Zhou et al.   ONCOGENE

Synchronizing Nuclear Import of Ribosomal Proteins with Ribosome Assembly

(2012) D. Kressler et al.   SCIENCE

Single-vector inducible lentiviral RNAi system for oncology target validation

(2011) Dmitri Wiederschain et al.   CELL CYCLE

A Proteome-wide, Quantitative Survey of In Vivo Ubiquitylation Sites Reveals Widespread Regulatory Roles

(2011) Sebastian A. Wagner et al.   MOLECULAR & CELLULAR PROTEOMICS

Systematic and Quantitative Assessment of the Ubiquitin-Modified Proteome

(2011) Woong Kim et al.   MOLECULAR CELL

The Structure of the Eukaryotic Ribosome at 3.0 A Resolution

(2011) A. Ben-Shem et al.   SCIENCE

Ribosomopathies: human disorders of ribosome dysfunction

(2010) A. Narla et al.   BLOOD

Identification of Aneuploidy-Tolerating Mutations

(2010) Eduardo M. Torres et al.   CELL

Ubiquitin-mediated mRNP dynamics and surveillance prior to budding yeast mRNA export

(2010) N. Iglesias et al.   GENES & DEVELOPMENT

A dual function for chaperones SSB–RAC and the NAC nascent polypeptide–associated complex on ribosomes

(2010) Ansgar Koplin et al.   JOURNAL OF CELL BIOLOGY

When ribosomes go bad: diseases of ribosome biogenesis

(2010) Emily F. Freed et al.   Molecular BioSystems

Role of a ribosome-associated E3 ubiquitin ligase in protein quality control

(2010) Mario H. Bengtson et al.   NATURE

Exome Sequencing Reveals VCP Mutations as a Cause of Familial ALS

(2010) Janel O. Johnson et al.   NEURON

Negative regulation of HDM2 to attenuate p53 degradation by ribosomal protein L26

(2010) Y. Zhang et al.   NUCLEIC ACIDS RESEARCH

The Genetic Landscape of a Cell

(2010) M. Costanzo et al.   SCIENCE

Driving ribosome assembly

(2009) Dieter Kressler et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

What the nucleolus says to a tumour pathologist

(2009) Massimo Derenzini et al.   HISTOPATHOLOGY

Histone levels are regulated by phosphorylation and ubiquitylation-dependent proteolysis

(2009) Rakesh Kumar Singh et al.   NATURE CELL BIOLOGY

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Cytoplasmic protein quality control degradation mediated by parallel actions of the E3 ubiquitin ligases Ubr1 and San1

(2009) J. W. Heck et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nucleolus, Ribosomes, and Cancer

(2008) Lorenzo Montanaro et al.   AMERICAN JOURNAL OF PATHOLOGY

Degradation of misfolded protein in the cytoplasm is mediated by the ubiquitin ligase Ubr1

(2008) Frederik Eisele et al.   FEBS LETTERS

Misfolded proteins partition between two distinct quality control compartments

(2008) Daniel Kaganovich et al.   NATURE

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

One step at a time: endoplasmic reticulum-associated degradation

(2008) Shruthi S. Vembar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH

A vector system for efficient and economical switching of C-terminal epitope tags inSaccharomyces cerevisiae

(2008) Min-Kyung Sung et al.   YEAST