Synaptic pruning in the female hippocampus is triggered at puberty by extrasynaptic GABAA receptors on dendritic spines

Mice null for NEDD9 (HEF1) display extensive hippocampal dendritic spine loss and cognitive impairment

(2016) D.C. Knutson et al.   BRAIN RESEARCH

Cc2d1a Loss of Function Disrupts Functional and Morphological Development in Forebrain Neurons Leading to Cognitive and Social Deficits

(2016) Adam W. Oaks et al.   CEREBRAL CORTEX

Schizophrenia risk from complex variation of complement component 4

(2016) Aswin Sekar et al.   NATURE

Complement C3-Deficient Mice Fail to Display Age-Related Hippocampal Decline

(2015) Q. Shi et al.   JOURNAL OF NEUROSCIENCE

Axin Regulates Dendritic Spine Morphogenesis through Cdc42-Dependent Signaling

(2015) Yu Chen et al.   PLoS One

Dynamics of nascent and active zone ultrastructure as synapses enlarge during long-term potentiation in mature hippocampus

(2014) Maria Elizabeth Bell et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Nonenzymatic domains of Kalirin7 contribute to spine morphogenesis through interactions with phosphoinositides and Abl

(2014) Xin-Ming Ma et al.   MOLECULAR BIOLOGY OF THE CELL

Loss of mTOR-Dependent Macroautophagy Causes Autistic-like Synaptic Pruning Deficits

(2014) Guomei Tang et al.   NEURON

Hampered long-term depression and thin spine loss in the nucleus accumbens of ethanol-dependent rats

(2014) S. Spiga et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Memantine Protects Rats Treated with Intrathecal Methotrexate from Developing Spatial Memory Deficits

(2013) P. D. Cole et al.   CLINICAL CANCER RESEARCH

LTP-Induced Long-Term Stabilization of Individual Nascent Dendritic Spines

(2013) T. C. Hill et al.   JOURNAL OF NEUROSCIENCE

Periadolescent Exposure to the NMDA Receptor Antagonist MK-801 Impairs the Functional Maturation of Local GABAergic Circuits in the Adult Prefrontal Cortex

(2013) D. R. Thomases et al.   JOURNAL OF NEUROSCIENCE

Changes in the plastic properties of hippocampal dendritic spines underlie the attenuation of place learning in healthy aged rats

(2013) Myrna M. González-Ramírez et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Reduced behavioral flexibility in autism spectrum disorders.

(2013) Anna-Maria D'Cruz et al.   NEUROPSYCHOLOGY

Dizocilpine reduces head diameter of dendritic spines in the hippocampus of adolescent rats

(2013) Dai Han et al.   PSYCHIATRY RESEARCH

Dendritic remodeling in the adolescent medial prefrontal cortex and the basolateral amygdala of male and female rats

(2013) Wendy A. Koss et al.   SYNAPSE

Inhibition of α5 γ-Aminobutyric Acid Type A Receptors Restores Recognition Memory After General Anesthesia

(2012) Agnieszka A. Zurek et al.   ANESTHESIA AND ANALGESIA

Knockout of the γ-aminobutyric acid receptor subunit α4 reduces functional δ-containing extrasynaptic receptors in hippocampal pyramidal cells at the onset of puberty

(2012) Nicole Sabaliauskas et al.   BRAIN RESEARCH

Structural Dynamics of Dendritic Spines are Influenced by an Environmental Enrichment: An In Vivo Imaging Study

(2012) Christian K.E. Jung et al.   CEREBRAL CORTEX

Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner

(2012) Dorothy P. Schafer et al.   NEURON

Sex, puberty, and the timing of sleep EEG measured adolescent brain maturation

(2012) I. G. Campbell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IQGAP1 Regulates NR2A Signaling, Spine Density, and Cognitive Processes

(2011) C. Gao et al.   JOURNAL OF NEUROSCIENCE

When Is the Hippocampus Involved in Recognition Memory?

(2011) G. R. I. Barker et al.   JOURNAL OF NEUROSCIENCE

Prolonged exposure to NMDAR antagonist induces cell-type specific changes of glutamatergic receptors in rat prefrontal cortex

(2011) Huai-Xing Wang et al.   NEUROPHARMACOLOGY

Extraordinary neoteny of synaptic spines in the human prefrontal cortex

(2011) Zdravko Petanjek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adolescent female rats exhibiting activity-based anorexia express elevated levels of GABAA receptor α4 and δ subunits at the plasma membrane of hippocampal CA1 spines

(2011) Chiye Aoki et al.   SYNAPSE

Increase of mushroom spine density in CA1 apical dendrites produced by water maze training is prevented by ovariectomy

(2010) V. Beltrán-Campos et al.   BRAIN RESEARCH

Synapse Pathology in Psychiatric and Neurologic Disease

(2010) Myrrhe van Spronsen et al.   Current Neurology and Neuroscience Reports

The point mutation γ2F77I changes the potency and efficacy of benzodiazepine site ligands in different GABAA receptor subtypes

(2010) Joachim Ramerstorfer et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Kalirin-7, an important component of excitatory synapses, is regulated by estradiol in hippocampal neurons

(2010) Xin-Ming Ma et al.   HIPPOCAMPUS

Selective Changes in Thin Spine Density and Morphology in Monkey Prefrontal Cortex Correlate with Aging-Related Cognitive Impairment

(2010) D. Dumitriu et al.   JOURNAL OF NEUROSCIENCE

A Critical Role for  4   GABAA Receptors in Shaping Learning Deficits at Puberty in Mice

(2010) H. Shen et al.   SCIENCE

Increased dendritic spine densities on cortical projection neurons in autism spectrum disorders

(2009) Jeffrey J. Hutsler et al.   BRAIN RESEARCH

Experience-Dependent, Rapid Structural Changes in Hippocampal Pyramidal Cell Spines

(2009) Takuma Kitanishi et al.   CEREBRAL CORTEX

Dizocilpine (MK-801) induces distinct changes of N-methyl-d-aspartic acid receptor subunits in parvalbumin-containing interneurons in young adult rat prefrontal cortex

(2009) Dong Xi et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Altered Expression of Genes Involved in GABAergic Transmission and Neuromodulation of Granule Cell Activity in the Cerebellum of Schizophrenia Patients

(2008) W. Michael Bullock et al.   AMERICAN JOURNAL OF PSYCHIATRY

NMDA Receptor Subunit NR2A Is Required for Rapidly Acquired Spatial Working Memory But Not Incremental Spatial Reference Memory

(2008) D. M. Bannerman et al.   JOURNAL OF NEUROSCIENCE

Kalirin-7 Is Required for Synaptic Structure and Function

(2008) X.-M. Ma et al.   JOURNAL OF NEUROSCIENCE

Transgenic Mice Lacking NMDAR-Dependent LTD Exhibit Deficits in Behavioral Flexibility

(2008) Russell E. Nicholls et al.   NEURON

Investigation of the anticonvulsive effect of acute immobilization stress in anxious Balb/cByJ mice using GABAA-related mechanistic probes

(2008) Marc Verleye et al.   PSYCHOPHARMACOLOGY

Postpubertal decrease in hippocampal dendritic spines of female rats

(2007) Murat Yildirim et al.   EXPERIMENTAL NEUROLOGY