Mapping translation 'hot-spots' in live cells by tracking single molecules of mRNA and ribosomes

Quantifying Protein-mRNA Interactions in Single Live Cells

(2015) Bin Wu et al.   CELL

Integration of actin dynamics and cell adhesion by a three-dimensional, mechanosensitive molecular clutch

(2015) Lindsay B. Case et al.   NATURE CELL BIOLOGY

Inferring transient particle transport dynamics in live cells

(2015) Nilah Monnier et al.   NATURE METHODS

An RNA biosensor for imaging the first round of translation from single cells to living animals

(2015) J. M. Halstead et al.   SCIENCE

Multiple Spatial and Kinetic Subpopulations of CaMKII in Spines and Dendrites as Resolved by Single-Molecule Tracking PALM

(2014) H. E. Lu et al.   JOURNAL OF NEUROSCIENCE

Direct observation of mobility state transitions in RNA trajectories by sensitive single molecule feedback tracking

(2014) Jan-Hendrik Spille et al.   NUCLEIC ACIDS RESEARCH

Single-molecule tracking in live cells reveals distinct target-search strategies of transcription factors in the nucleus

(2014) Ignacio Izeddin et al.   eLife

Mathematical Modeling of Eukaryotic Cell Migration: Insights Beyond Experiments

(2013) Gaudenz Danuser et al.   Annual Review of Cell and Developmental Biology

ViSP: representing single-particle localizations in three dimensions

(2013) Mohamed El Beheiry et al.   NATURE METHODS

Real-Time Dynamics of RNA Polymerase II Clustering in Live Human Cells

(2013) I. I. Cisse et al.   SCIENCE

Taking a cellular road-trip: mRNA transport and anchoring

(2012) Catherine A Pratt et al.   CURRENT OPINION IN CELL BIOLOGY

 -Actin mRNA compartmentalization enhances focal adhesion stability and directs cell migration

(2012) Z. B. Katz et al.   GENES & DEVELOPMENT

Spatial arrangement of an RNA zipcode identifies mRNAs under post-transcriptional control

(2012) V. L. Patel et al.   GENES & DEVELOPMENT

Single-molecule analysis of gene expression using two-color RNA labeling in live yeast

(2012) Sami Hocine et al.   NATURE METHODS

An Unbiased Analysis Method to Quantify mRNA Localization Reveals Its Correlation with Cell Motility

(2012) Hye Yoon Park et al.   Cell Reports

FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism

(2011) Jennifer C. Darnell et al.   CELL

Ribosome Profiling of Mouse Embryonic Stem Cells Reveals the Complexity and Dynamics of Mammalian Proteomes

(2011) Nicholas T. Ingolia et al.   CELL

Global quantification of mammalian gene expression control

(2011) Björn Schwanhäusser et al.   NATURE

A transgenic mouse for in vivo detection of endogenous labeled mRNA

(2011) Timothée Lionnet et al.   NATURE METHODS

Adhesive F-actin Waves: A Novel Integrin-Mediated Adhesion Complex Coupled to Ventral Actin Polymerization

(2011) Lindsay B. Case et al.   PLoS One

In vivo imaging of labelled endogenous β-actin mRNA during nucleocytoplasmic transport

(2010) David Grünwald et al.   NATURE

Nanoscale architecture of integrin-based cell adhesions

(2010) Pakorn Kanchanawong et al.   NATURE

Size-dependent accumulation of mRNA at the leading edge of chicken embryo fibroblasts

(2009) Mai Yamagishi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Single-molecule imaging of β-actin mRNAs in the cytoplasm of a living cell

(2009) Mai Yamagishi et al.   EXPERIMENTAL CELL RESEARCH

The ribosome as a platform for co-translational processing, folding and targeting of newly synthesized proteins

(2009) Günter Kramer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Subcellular mRNA Localization in Animal Cells and Why It Matters

(2009) C. E. Holt et al.   SCIENCE