Evolution-guided functional analyses reveal diverse antiviral specificities encoded by IFIT1 genes in mammals

Molecular Evolution of the CYP2D Subfamily in Primates: Purifying Selection on Substrate Recognition Sites without the Frequent or Long-Tract Gene Conversion

(2015) Yoshiki Yasukochi et al.   Genome Biology and Evolution

Human and Murine IFIT1 Proteins Do Not Restrict Infection of Negative-Sense RNA Viruses of the Orthomyxoviridae, Bunyaviridae, and Filoviridae Families

(2015) Amelia K. Pinto et al.   JOURNAL OF VIROLOGY

To translate, or not to translate: viral and host mRNA regulation by interferon-stimulated genes

(2015) Melody M.H. Li et al.   TRENDS IN CELL BIOLOGY

Innate immune restriction and antagonism of viral RNA lacking 2׳-O methylation

(2015) Jennifer L. Hyde et al.   VIROLOGY

Evolutionary Analyses Suggest a Function of MxB Immunity Proteins Beyond Lentivirus Restriction

(2015) Patrick S. Mitchell et al.   PLoS Pathogens

Interferon-Stimulated Genes: A Complex Web of Host Defenses

(2014) William M. Schneider et al.   Annual Review of Immunology

IFIT1: A dual sensor and effector molecule that detects non-2′-O methylated viral RNA and inhibits its translation

(2014) Michael S. Diamond   CYTOKINE & GROWTH FACTOR REVIEWS

Attenuation and Restoration of Severe Acute Respiratory Syndrome Coronavirus Mutant Lacking 2'-O-Methyltransferase Activity

(2014) V. D. Menachery et al.   JOURNAL OF VIROLOGY

Interferon-Induced Ifit Proteins: Their Role in Viral Pathogenesis

(2014) Volker Fensterl et al.   JOURNAL OF VIROLOGY

Interferon-Induced Genes of the Expanded IFIT Family Show Conserved Antiviral Activities in Non-Mammalian Species

(2014) Mónica Varela et al.   PLoS One

Broad and adaptable RNA structure recognition by the human interferon-induced tetratricopeptide repeat protein IFIT5

(2014) G. E. Katibah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Viral RNA Structural Element Alters Host Recognition of Nonself RNA

(2014) J. L. Hyde et al.   SCIENCE

Interferon-stimulated genes: roles in viral pathogenesis

(2014) John W Schoggins   Current Opinion in Virology

Evolution of Innate Immunity: Clues from Invertebrates via Fish to Mammals

(2014) Kurt Buchmann   Frontiers in Immunology

IFITs: Emerging Roles as Key Anti-Viral Proteins

(2014) Gregory I. Vladimer et al.   Frontiers in Immunology

Ifit1 Inhibits Japanese Encephalitis Virus Replication through Binding to 5' Capped 2'-O Unmethylated RNA

(2013) T. Kimura et al.   JOURNAL OF VIROLOGY

mRNA Cap Methylation Influences Pathogenesis of Vesicular Stomatitis Virus In Vivo

(2013) Y. Ma et al.   JOURNAL OF VIROLOGY

tRNA Binding, Structure, and Localization of the Human Interferon-Induced Protein IFIT5

(2013) George E. Katibah et al.   MOLECULAR CELL

Structural basis for viral 5′-PPP-RNA recognition by human IFIT proteins

(2013) Yazan M. Abbas et al.   NATURE

Inhibition of translation by IFIT family members is determined by their ability to interact selectively with the 5'-terminal regions of cap0-, cap1- and 5'ppp- mRNAs

(2013) P. Kumar et al.   NUCLEIC ACIDS RESEARCH

Lineage-Specific Expansion of IFIT Gene Family: An Insight into Coevolution with IFN Gene Family

(2013) Ying Liu et al.   PLoS One

The Placental Mammal Ancestor and the Post-K-Pg Radiation of Placentals

(2013) M. A. O'Leary et al.   SCIENCE

Sequestration by IFIT1 Impairs Translation of 2′O-unmethylated Capped RNA

(2013) Matthias Habjan et al.   PLoS Pathogens

Rules of Engagement: Molecular Insights from Host-Virus Arms Races

(2012) Matthew D. Daugherty et al.   Annual Review of Genetics

Geneious Basic: An integrated and extendable desktop software platform for the organization and analysis of sequence data

(2012) M. Kearse et al.   BIOINFORMATICS

An ancient history of gene duplications, fusions and losses in the evolution of APOBEC3 mutators in mammals

(2012) Carsten Münk et al.   BMC EVOLUTIONARY BIOLOGY

Host Translation at the Nexus of Infection and Immunity

(2012) Ian Mohr et al.   Cell Host & Microbe

Crystal structure of ISG54 reveals a novel RNA binding structure and potential functional mechanisms

(2012) Zhenlin Yang et al.   CELL RESEARCH

Extensive evolutionary and functional diversity among mammalian AIM2-like receptors

(2012) Rebecca L. Brunette et al.   JOURNAL OF EXPERIMENTAL MEDICINE

ISG56/IFIT1 is primarily responsible for interferon-induced changes to patterns of parainfluenza virus type 5 transcription and protein synthesis

(2012) J. Andrejeva et al.   JOURNAL OF GENERAL VIROLOGY

Evolutionary Dynamics of the Interferon-Induced Transmembrane Gene Family in Vertebrates

(2012) Zhao Zhang et al.   PLoS One

2′-O Methylation of the Viral mRNA Cap by West Nile Virus Evades Ifit1-Dependent and -Independent Mechanisms of Host Restriction In Vivo

(2012) Kristy J. Szretter et al.   PLoS Pathogens

Conversion events in gene clusters

(2011) Giltae Song et al.   BMC EVOLUTIONARY BIOLOGY

Gene conversions in the growth hormone gene family of primates: Stronger homogenizing effects in the Hominidae lineage

(2011) Nicholas Petronella et al.   GENOMICS

ISG56 and IFITM1 Proteins Inhibit Hepatitis C Virus Replication

(2011) A. Raychoudhuri et al.   JOURNAL OF VIROLOGY

Ribose 2′-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5

(2011) Roland Züst et al.   NATURE IMMUNOLOGY

IFIT1 is an antiviral protein that recognizes 5′-triphosphate RNA

(2011) Andreas Pichlmair et al.   NATURE IMMUNOLOGY

Conventional and unconventional mechanisms for capping viral mRNA

(2011) Etienne Decroly et al.   NATURE REVIEWS MICROBIOLOGY

Characterization of hMTr1, a Human Cap1 2′-O-Ribose Methyltransferase

(2010) François Bélanger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The ISG56/IFIT1 Gene Family

(2010) Volker Fensterl et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

2′-O methylation of the viral mRNA cap evades host restriction by IFIT family members

(2010) Stephane Daffis et al.   NATURE

New Algorithms and Methods to Estimate Maximum-Likelihood Phylogenies: Assessing the Performance of PhyML 3.0

(2010) Stéphane Guindon et al.   SYSTEMATIC BIOLOGY

An expanded clade of rodent Trim5 genes

(2009) Semih U. Tareen et al.   VIROLOGY

Interferon-inducible protein, P56, inhibits HPV DNA replication by binding to the viral protein E1

(2008) Fulvia Terenzi et al.   EMBO JOURNAL

Ectopic gene conversions in the human genome

(2008) David Benovoy et al.   GENOMICS