标题
Domain-swapped T cell receptors improve the safety of TCR gene therapy
作者
关键词
-
出版物
eLife
Volume 5, Issue -, Pages -
出版商
eLife Sciences Organisation, Ltd.
发表日期
2016-11-08
DOI
10.7554/elife.19095
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Immune Checkpoint Blockade: A Common Denominator Approach to Cancer Therapy
- (2015) Suzanne L. Topalian et al. CANCER CELL
- Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
- (2015) Padmanee Sharma et al. CELL
- The T cell antigen receptor: the Swiss army knife of the immune system
- (2015) M. Attaf et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Nivolumab: targeting PD-1 to bolster antitumor immunity
- (2015) Julie R Brahmer et al. Future Oncology
- A Mechanical Switch Couples T Cell Receptor Triggering to the Cytoplasmic Juxtamembrane Regions of CD3ζζ
- (2015) Mark S. Lee et al. IMMUNITY
- TCR-Mediated Recognition: Relevance to Tumor-Antigen Discovery and Cancer Immunotherapy
- (2015) E. L. Reinherz Cancer Immunology Research
- HSV-sr39TK Positron Emission Tomography and Suicide Gene Elimination of Human Hematopoietic Stem Cells and Their Progeny in Humanized Mice
- (2014) E. H. Gschweng et al. CANCER RESEARCH
- Adoptive Transfer of MART-1 T-Cell Receptor Transgenic Lymphocytes and Dendritic Cell Vaccination in Patients with Metastatic Melanoma
- (2014) T. Chodon et al. CLINICAL CANCER RESEARCH
- A Pilot Trial Using Lymphocytes Genetically Engineered with an NY-ESO-1-Reactive T-cell Receptor: Long-term Follow-up and Correlates with Response
- (2014) P. F. Robbins et al. CLINICAL CANCER RESEARCH
- CD4+CD25- T Cells Transduced to Express MHC Class I-Restricted Epitope-Specific TCR Synthesize Th1 Cytokines and Exhibit MHC Class I-Restricted Cytolytic Effector Function in a Human Melanoma Model
- (2014) A. Chhabra et al. JOURNAL OF IMMUNOLOGY
- T Cell Receptor Transfer to T Cells Generates Functional Effector Cells without Mixed TCR Dimers In Vivo
- (2014) L. T. van der Veken et al. JOURNAL OF IMMUNOLOGY
- RNAi-mediated TCR Knockdown Prevents Autoimmunity in Mice Caused by Mixed TCR Dimers Following TCR Gene Transfer
- (2014) Mario Bunse et al. MOLECULAR THERAPY
- Cardiovascular toxicity and titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma
- (2013) G. P. Linette et al. BLOOD
- Expression profiling of TCR-engineered T cells demonstrates overexpression of multiple inhibitory receptors in persisting lymphocytes
- (2013) D. Abate-Daga et al. BLOOD
- Cancer Regression and Neurological Toxicity Following Anti-MAGE-A3 TCR Gene Therapy
- (2013) Richard A. Morgan et al. JOURNAL OF IMMUNOTHERAPY
- Allelic Exclusion and Peripheral Reconstitution by TCR Transgenic T Cells Arising From Transduced Human Hematopoietic Stem/Progenitor Cells
- (2013) Francesca Giannoni et al. MOLECULAR THERAPY
- Introduction of Exogenous T-cell Receptors Into Human Hematopoietic Progenitors Results in Exclusion of Endogenous T-cell Receptor Expression
- (2013) Dimitrios N Vatakis et al. MOLECULAR THERAPY
- Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer
- (2012) Elena Provasi et al. NATURE MEDICINE
- Tumor Regression in Patients With Metastatic Synovial Cell Sarcoma and Melanoma Using Genetically Engineered Lymphocytes Reactive With NY-ESO-1
- (2011) Paul F. Robbins et al. JOURNAL OF CLINICAL ONCOLOGY
- Cancer immunotherapy comes of age
- (2011) Ira Mellman et al. NATURE
- A clinical microchip for evaluation of single immune cells reveals high functional heterogeneity in phenotypically similar T cells
- (2011) Chao Ma et al. NATURE MEDICINE
- Antitumor activity from antigen-specific CD8 T cells generated in vivo from genetically engineered human hematopoietic stem cells
- (2011) D. N. Vatakis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Immunoglobulin domain crossover as a generic approach for the production of bispecific IgG antibodies
- (2011) W. Schaefer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Treating cancer with genetically engineered T cells
- (2011) Tristen S. Park et al. TRENDS IN BIOTECHNOLOGY
- Human effector CD8+ T cells derived from naive rather than memory subsets possess superior traits for adoptive immunotherapy
- (2010) C. S. Hinrichs et al. BLOOD
- Development of Human Anti-Murine T-Cell Receptor Antibodies in Both Responding and Nonresponding Patients Enrolled in TCR Gene Therapy Trials
- (2010) J. L. Davis et al. CLINICAL CANCER RESEARCH
- Of Mice, Not Men: No Evidence for Graft-versus-Host Disease in Humans Receiving T-Cell Receptor–Transduced Autologous T Cells
- (2010) Steven A Rosenberg MOLECULAR THERAPY
- Case Report of a Serious Adverse Event Following the Administration of T Cells Transduced With a Chimeric Antigen Receptor Recognizing ERBB2
- (2010) Richard A Morgan et al. MOLECULAR THERAPY
- T Cells Targeting Carcinoembryonic Antigen Can Mediate Regression of Metastatic Colorectal Cancer but Induce Severe Transient Colitis
- (2010) Maria R Parkhurst et al. MOLECULAR THERAPY
- Lethal graft-versus-host disease in mouse models of T cell receptor gene therapy
- (2010) Gavin M Bendle et al. NATURE MEDICINE
- Mixed T cell receptor dimers harbor potentially harmful neoreactivity
- (2010) M. M. van Loenen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Evidence for a functional sidedness to the TCR
- (2010) M. S. Kuhns et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen
- (2009) L. A. Johnson et al. BLOOD
- TCR transgenes and transgene cassettes for TCR gene therapy: status in 2008
- (2009) Wolfgang Uckert et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Improved Expression and Reactivity of Transduced Tumor-Specific TCRs in Human Lymphocytes by Specific Silencing of Endogenous TCR
- (2009) S. Okamoto et al. CANCER RESEARCH
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now