Review
Rehabilitation
Kristin J. Konnyu, Louise M. Thoma, Wangnan Cao, Roy K. Aaron, Orestis A. Panagiotou, Monika Reddy Bhuma, Gaelen P. Adam, Dan Pinto, Ethan M. Balk
Summary: This study systematically reviewed the evidence on prehabilitation interventions for patients undergoing elective knee or hip arthroplasty for osteoarthritis. Thirteen knee arthroplasty trials suggested that prehabilitation may improve strength and reduce hospital stay without increasing harms, but there was insufficient evidence for pain, range of motion, and daily activities. There was no evidence or insufficient evidence for all outcomes of hip arthroplasty.
AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION
(2023)
Review
Medicine, General & Internal
Chuan Hong, Hai-Yan Xie, Wu-Kun Ge, Min Yu, Shuai-nan Lin, Cheng-Jiang Liu
Summary: This study conducted a meta-analysis and systematic review on the analgesic treatment of parecoxib in total knee or total hip arthroplasty. The results showed that parecoxib can reduce the incidence of adverse events to some extent, but it does not have a significant impact on the incidence of nausea and vomiting. The analgesic effect at 24 hours is better than placebo, but it is the same as placebo at 48 hours.
Review
Orthopedics
Stephanie Marrannes, Klaas Victor, Nele Arnout, Tine De Backer, Jan Victor, Thomas Tampere
Summary: A systematic review comparing the effectiveness of aspirin prophylaxis following knee surgery with other standard prophylactic agents found no significant difference in VTE prevention between aspirin, LMWH, and warfarin, while factor Xa inhibitors were more effective but also associated with increased bleeding complications. Additional research with high-quality trials is needed due to limited evidence and substantial heterogeneity.
EFORT OPEN REVIEWS
(2021)
Review
Orthopedics
Chen Xi Kasia Chua, Joelle Hwee Inn Tan, Hamid Rahmatullah Bin Abd Razak
Summary: This systematic review and meta-analysis evaluated the efficacy of direct oral anticoagulants (DOACs) compared with enoxaparin in an Asian population after total knee arthroplasty (TKA). The results showed that DOACs significantly reduced the rate of overall venous thromboembolism (VTE) compared with enoxaparin. However, there were no significant differences in deep vein thrombosis, pulmonary embolism, and rates of bleeding complications between the two.
JOURNAL OF ARTHROPLASTY
(2022)
Review
Orthopedics
Aidan T. Morrell, Daniel R. Layon, Michael J. Scott, Stephen L. Kates, Gregory J. Golladay, Nirav K. Patel
Summary: The study systematically reviewed the effect of ERAS after primary elective total hip arthroplasty (THA) or total knee arthroplasty (TKA), showing that ERAS can significantly reduce hospital length of stay and have a modest effect on procedure-related morbidity, but no significant impact on readmission rates.
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
(2021)
Review
Hematology
Sheng Xu, Jerry Yongqiang Chen, Qishi Zheng, Luming Shi, Andrew Hwee Chye Tan
Summary: Asians undergoing Total Joint Arthroplasty have lower incidence of VTE compared to Western population. Although Enoxaparin is still effective in reducing symptomatic and proximal DVT after TJA, its benefit-to-risk ratio is lower than described in Western literature.
THROMBOSIS RESEARCH
(2021)
Review
Anesthesiology
Paul Panzenbeck, Arvind von Keudell, Girish P. Joshi, Claire X. Xu, Kamen Vlassakov, Kristin L. Schreiber, James P. Rathmell, Philipp Lirk
Summary: The study conducted a systematic search and analysis of analgesic trials for total hip arthroplasty (THA), finding that in most patients undergoing THA under general anaesthesia, postoperative acute pain should subside to a mild level within 4 hours. However, there remains a substantial knowledge gap in the management of patients with chronic pain and opioid dependence.
BRITISH JOURNAL OF ANAESTHESIA
(2021)
Review
Orthopedics
Michael W. Seward, Logan G. Briggs, Paul A. Bain, Antonia F. Chen
Summary: This systematic review examined nonsurgical weight loss interventions before total joint arthroplasty (TJA) for obese patients. The results showed that these interventions can lead to significant weight loss and reduced BMI before surgery, but it is unclear whether the amount of weight loss is clinically significant and sufficient to improve outcomes after TJA.
JOURNAL OF ARTHROPLASTY
(2021)
Review
Pharmacology & Pharmacy
Yi-hu Yi, Song Gong, Tian-lun Gong, Ling-yun Zhou, Can Hu, Wei-hua Xu
Summary: NOACs are beneficial for VTE prophylaxis in patients undergoing total hip and knee arthroplasty, with rivaroxaban showing the most benefits in VTE prevention. None of the individual NOACs increased the risk of bleeding, and apixaban and betrixaban even decreased the risk of bleeding.
FRONTIERS IN PHARMACOLOGY
(2022)
Review
Medicine, General & Internal
Lissa Pacheco-Brousseau, Marylene Charette, Dawn Stacey, Stephane Poitras
Summary: This systematic review aims to evaluate the effect of patient decision aids on decision-making quality and process for adults with knee and hip osteoarthritis considering primary elective TJA. It will provide evidence on different types of PtDAs used for TJA decision-making and inform further research on joint replacement decision-making quality and processes.
SYSTEMATIC REVIEWS
(2021)
Review
Orthopedics
Quan Zhou, Xinfeng Zhou, Yijian Zhang, Mingzhuang Hou, Xin Tian, Huilin Yang, Fan He, Xi Chen, Tao Liu
Summary: The study aimed to investigate predictors of delirium after total joint arthroplasty in elderly patients. The results showed that factors such as advanced age, dementia, hypertension, diabetes, stroke, psychiatric illness, use of sedative-hypnotics, lower preoperative levels of hemoglobin, and lower preoperative mini-mental state examination score were associated with postoperative delirium. Strategies and interventions should be implemented for elderly patients receiving TJA surgeries with these potential predictors identified in this meta-analysis.
BMC MUSCULOSKELETAL DISORDERS
(2021)
Review
Orthopedics
L. Pacheco-Brousseau, D. Stacey, F. Desmeules, S. Ben Amor, D. Lambert, E. Tanguay, A. Hillaby, C. Bechiau, M. Charette, S. Poitras
Summary: This study aimed to assess the criteria and psychometric properties of instruments for evaluating the appropriateness of elective joint arthroplasty for adults with primary hip and knee osteoarthritis. The results showed that most instruments included traditional criteria but lacked elements of conservative treatments or shared decision-making. There was limited evidence regarding the psychometric properties.
OSTEOARTHRITIS AND CARTILAGE
(2023)
Article
Orthopedics
Vincent J. Leopold, Paula Krull, Sebastian Hardt, Christian Hipfl, Oliver Melsheimer, Arnd Steinbrueck, Carsten Perka, Gregor M. Giebel
Summary: The study found that nonagenarians undergoing elective total hip arthroplasty (THA) had higher morbidity and mortality rates, with major risk factors including congestive heart failure, pulmonary circulation disorders, insulin-dependent diabetes, among others. However, careful patient selection and adequate preparation can help control mortality rates, as shown by the fact that mortality rates in nonagenarians were lower than in the general population.
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
(2023)
Review
Pharmacology & Pharmacy
Weili Feng, Xiaoping Wang, Daoqiang Huang, Anqi Lu
Summary: This study conducted a systematic review and network meta-analysis to assess the efficacy of 19 anticoagulants in preventing venous thromboembolism and bleeding during total knee or total hip arthroplasty. Results indicated that Apixaban, Edoxaban, and Darexaban were superior in preventing VTE and bleeding. Enoxaparin, although not the most effective, showed stable efficacy and safety.
PHARMACOLOGICAL RESEARCH
(2021)
Article
Orthopedics
Utkarsh Anil, Noah Kirschner, Greg M. Teo, Katherine A. Lygrisse, Chelsea S. Sicat, Ran Schwarzkopf, Vinay K. Aggarwal, William J. Long
Summary: This study aimed to evaluate the effect of thromboprophylaxis choice on the rates of early prosthetic joint infection (PJI) following total knee arthroplasty (TKA). The results showed that patients given aspirin thromboprophylaxis had a significantly lower rate of early PJI compared to non-aspirin patients. Therefore, arthroplasty surgeons should consider aspirin as the gold standard thromboprophylaxis in all patients and carefully weigh the morbidity of PJI when considering non-aspirin thromboprophylaxis.
JOURNAL OF ARTHROPLASTY
(2023)