Autophagy Promoted the Degradation of Mutant ATXN3 in Neurally Differentiated Spinocerebellar Ataxia-3 Human Induced Pluripotent Stem Cells

Generation of spinocerebellar ataxia type 3 patient-derived induced pluripotent stem cell line SCA3.B11

(2016) Susanne K. Hansen et al.   Stem Cell Research

Autophagy and mTORC1 regulate the stochastic phase of somatic cell reprogramming

(2015) Yasong Wu et al.   NATURE CELL BIOLOGY

Toward therapeutic targets for SCA3: Insight into the role of Machado–Joseph disease protein ataxin-3 in misfolded proteins clearance

(2015) Xiaoling Li et al.   PROGRESS IN NEUROBIOLOGY

Improved Hematopoietic Differentiation Efficiency of Gene-Corrected Beta-Thalassemia Induced Pluripotent Stem Cells by CRISPR/Cas9 System

(2015) Bing Song et al.   STEM CELLS AND DEVELOPMENT

Prader-Willi Syndrome With a Long-Contiguous Stretch of Homozygosity Not Covering the Critical Region

(2014) Xie Yingjun et al.   JOURNAL OF CHILD NEUROLOGY

MicroRNA-34a Modulates Neural Stem Cell Differentiation by Regulating Expression of Synaptic and Autophagic Proteins

(2014) Ana L. Morgado et al.   MOLECULAR NEUROBIOLOGY

Chronic Treatment with 17-DMAG Improves Balance and Coordination in A New Mouse Model of Machado-Joseph Disease

(2014) Anabela Silva-Fernandes et al.   Neurotherapeutics

mir-30d Regulates multiple genes in the autophagy pathway and impairs autophagy process in human cancer cells

(2013) Xiaojun Yang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Autophagy Regulates Homeostasis of Pluripotency-Associated Proteins in hESCs

(2013) Yun-Hee Cho et al.   STEM CELLS

Efficient and Rapid Derivation of Primitive Neural Stem Cells and Generation of Brain Subtype Neurons From Human Pluripotent Stem Cells

(2013) Yiping Yan et al.   Stem Cells Translational Medicine

Generation of Human-Induced Pluripotent Stem Cells to Model Spinocerebellar Ataxia Type 2 In vitro

(2012) Guangbin Xia et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Shedding new light on neurodegenerative diseases through the mammalian target of rapamycin

(2012) Zhao Zhong Chong et al.   PROGRESS IN NEUROBIOLOGY

Generation of Induced Pluripotent Stem Cells from Skin Fibroblasts of a Patient with Olivopontocerebellar Atrophy

(2012) Yumei Luo et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

Overexpression of the autophagic beclin-1 protein clears mutant ataxin-3 and alleviates Machado–Joseph disease

(2011) Isabel Nascimento-Ferreira et al.   BRAIN

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

Lysosomal Proteolysis Inhibition Selectively Disrupts Axonal Transport of Degradative Organelles and Causes an Alzheimer's-Like Axonal Dystrophy

(2011) S. Lee et al.   JOURNAL OF NEUROSCIENCE

Excitation-induced ataxin-3 aggregation in neurons from patients with Machado–Joseph disease

(2011) Philipp Koch et al.   NATURE

Axonal inclusions in spinocerebellar ataxia type 3

(2010) Kay Seidel et al.   ACTA NEUROPATHOLOGICA

The role of the Atg1/ULK1 complex in autophagy regulation

(2010) Noboru Mizushima   CURRENT OPINION IN CELL BIOLOGY

Rapamycin Protects against Neuron Death in In Vitro andIn Vivo Models of Parkinson's Disease

(2010) C. Malagelada et al.   JOURNAL OF NEUROSCIENCE

Pathogenic Lysosomal Depletion in Parkinson's Disease

(2010) B. Dehay et al.   JOURNAL OF NEUROSCIENCE

A Modified Culture Medium Increases Blastocyst Formation and the Efficiency of Human Embryonic Stem Cell Derivation from Poor-Quality Embryos

(2010) Yong FAN et al.   JOURNAL OF REPRODUCTION AND DEVELOPMENT

Autophagy gone awry in neurodegenerative diseases

(2010) Esther Wong et al.   NATURE NEUROSCIENCE

Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease

(2010) Marta Martinez-Vicente et al.   NATURE NEUROSCIENCE

Autophagy induction reduces mutant ataxin-3 levels and toxicity in a mouse model of spinocerebellar ataxia type 3

(2009) Fiona M. Menzies et al.   BRAIN

Derivation and characterization of human embryonic stem cell lines from poor quality embryos

(2009) Weiqiang Liu et al.   Journal of Genetics and Genomics

Similar biological characteristics of human embryonic stem cell lines with normal and abnormal karyotypes

(2008) X. Sun et al.   HUMAN REPRODUCTION

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE

Roles of autophagy and mTOR signaling in neuronal differentiation of mouse neuroblastoma cells

(2007) Mei Zeng et al.   CELLULAR SIGNALLING