Chemically modified inulin microparticles serving dual function as a protein antigen delivery vehicle and immunostimulatory adjuvant

Evaluation of a biodegradable microparticulate polymer as a carrier for Burkholderia pseudomallei subunit vaccines in a mouse model of melioidosis

(2015) K.L. Schully et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Vaccine instability in the cold chain: Mechanisms, analysis and formulation strategies

(2014) Ozan S. Kumru et al.   BIOLOGICALS

Advax-Adjuvanted Recombinant Protective Antigen Provides Protection against Inhalational Anthrax That Is Further Enhanced by Addition of Murabutide Adjuvant

(2014) Brandon Feinen et al.   Clinical and Vaccine Immunology

Acetalated dextran encapsulated AR-12 as a host-directed therapy to control Salmonella infection

(2014) Ky V. Hoang et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Antigen Release Kinetics in the Phagosome Are Critical to Cross-Presentation Efficiency

(2014) S. W. Howland et al.   JOURNAL OF IMMUNOLOGY

Treatment of Experimental Autoimmune Encephalomyelitis by Codelivery of Disease Associated Peptide and Dexamethasone in Acetalated Dextran Microparticles

(2014) Kevin J. Peine et al.   MOLECULAR PHARMACEUTICS

Preparation, Characterization, In Vitro Release and Degradation of Cathelicidin-BF-30-PLGA Microspheres

(2014) Lili Li et al.   PLoS One

Tunable Protein Release from Acetalated Dextran Microparticles: A Platform for Delivery of Protein Therapeutics to the Heart Post-MI

(2013) Sophia Suarez et al.   BIOMACROMOLECULES

The polysaccharide inulin is characterized by an extensive series of periodic isoforms with varying biological actions

(2013) P. D. Cooper et al.   GLYCOBIOLOGY

Electrospun Acetalated Dextran Scaffolds for Temporal Release of Therapeutics

(2013) Hassan M. Borteh et al.   LANGMUIR

Novel Insights Into Appropriate Encapsulation Methods for Bioactive Compounds Into Polymers: A Study With Peptides and HDAC Inhibitors

(2013) Dorle Hennig et al.   MACROMOLECULAR BIOSCIENCE

Development of Soluble Inulin Microparticles as a Potent and Safe Vaccine Adjuvant and Delivery System

(2013) Sunny Kumar et al.   MOLECULAR PHARMACEUTICS

Electrospray Encapsulation of Toll-Like Receptor Agonist Resiquimod in Polymer Microparticles for the Treatment of Visceral Leishmaniasis

(2013) Anthony D. Duong et al.   MOLECULAR PHARMACEUTICS

Efficient Delivery of the Toll-like Receptor Agonists Polyinosinic:Polycytidylic Acid and CpG to Macrophages by Acetalated Dextran Microparticles

(2013) Kevin J. Peine et al.   MOLECULAR PHARMACEUTICS

Rapid Vaccination Using an Acetalated Dextran Microparticulate Subunit Vaccine Confers Protection Against Triplicate Challenge by Bacillus Anthracis

(2013) Kevin L. Schully et al.   PHARMACEUTICAL RESEARCH

Immune Modulation by Different Types of β2→1-Fructans Is Toll-Like Receptor Dependent

(2013) Leonie Vogt et al.   PLoS One

A novel hepatitis B vaccine containing Advax™, a polysaccharide adjuvant derived from delta inulin, induces robust humoral and cellular immunity with minimal reactogenicity in preclinical testing

(2013) Fadi Saade et al.   VACCINE

Synthesis and Characterization of Acetalated Dextran Polymer and Microparticles with Ethanol as a Degradation Product

(2012) Kevin J. Kauffman et al.   ACS Applied Materials & Interfaces

Engineering Nano- and Microparticles to Tune Immunity

(2012) James J. Moon et al.   ADVANCED MATERIALS

Enhanced stability of horseradish peroxidase encapsulated in acetalated dextran microparticles stored outside cold chain conditions

(2012) Naveen Kanthamneni et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Polyanhydride microparticles enhance dendritic cell antigen presentation and activation

(2011) Maria P. Torres et al.   Acta Biomaterialia

Facile Synthesis of Acid-Labile Polymers with Pendent Ortho Esters

(2011) Jing Cheng et al.   BIOMACROMOLECULES

Activation of innate immune responses in a pathogen-mimicking manner by amphiphilic polyanhydride nanoparticle adjuvants

(2011) Latrisha K. Petersen et al.   BIOMATERIALS

Studies onin vitroavailability, degradation, and thermal properties of naltrexone-loaded biodegradable microspheres

(2011) Emmamuel O. Akala et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

The long-term potential of biodegradable poly(lactideco-glycolide) microparticles as the next-generation vaccine adjuvant

(2011) Siddhartha Jain et al.   Expert Review of Vaccines

Optimization of rapamycin-loaded acetalated dextran microparticles for immunosuppression

(2011) Kevin J. Kauffman et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Synthesis, Optimization, and Characterization of Camptothecin-Loaded Acetalated Dextran Porous Microparticles for Pulmonary Delivery

(2011) Samantha A. Meenach et al.   MOLECULAR PHARMACEUTICS

Preservation of the Immunogenicity of Dry-powder Influenza H5N1 Whole Inactivated Virus Vaccine at Elevated Storage Temperatures

(2010) Felix Geeraedts et al.   AAPS Journal

Delta inulin: a novel, immunologically active, stable packing structure comprising  -D-[2 -> 1] poly(fructo-furanosyl)  -D-glucose polymers

(2010) P. D. Cooper et al.   GLYCOBIOLOGY

A comparison between spray drying and spray freeze drying to produce an influenza subunit vaccine powder for inhalation

(2010) V. Saluja et al.   JOURNAL OF CONTROLLED RELEASE

COMMENTARY: Acceptable Levels of Endotoxin in Vaccine Formulations During Preclinical Research

(2010) Luis A. Brito et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

In Vitro Analysis of Acetalated Dextran Microparticles as a Potent Delivery Platform for Vaccine Adjuvants

(2010) Eric M. Bachelder et al.   MOLECULAR PHARMACEUTICS

Poly(ortho ester amides): Acid-Labile Temperature-Responsive Copolymers for Potential Biomedical Applications

(2009) Rupei Tang et al.   BIOMACROMOLECULES

Acetalated dextran is a chemically and biologically tunable material for particulate immunotherapy

(2009) K. E. Broaders et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nanotechnology in vaccine delivery

(2008) Laura J. Peek et al.   ADVANCED DRUG DELIVERY REVIEWS

Biomaterials as vaccine adjuvants

(2008) Kim S. Jones   BIOTECHNOLOGY PROGRESS

Immunomodulatory biomaterials

(2008) Surya K. Mallapragada et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Acetal-Derivatized Dextran: An Acid-Responsive Biodegradable Material for Therapeutic Applications

(2008) Eric M. Bachelder et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY