Synthesis of Functionalized 2-Trifluoromethylquinolines and their Heteroaromatic Analogues

Electron-rich anilines and amino heterocycles were converted in one step into N-protected functionalized aminoethyl 2-trifluoromethylquinolines and their heteroaromatic analogues. The N-carbamate protecting group can be easily cleaved under acidic conditions to give the corresponding amines.