期刊
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
卷 4, 期 11, 页码 5900-5906出版社
AMER CHEMICAL SOC
DOI: 10.1021/acssuschemeng.6b02089
关键词
Molecular design; Reduced hazard; Principles of Green Chemistry; Toxicology; Sustainable innovation; Eco-innovation; Sustainability; Synthesis; Systems thinking; Property-based guidelines; Design rules; Preventative toxicology; Green toxicology; Life cycle assessment; Building blocks; ToxCast; Tox21; NSMDS; MoDRN
资金
- NSF Division of Chemistry
- EPA through a program of Networks for Sustainable Molecular Design and Synthesis [1339637]
Synthetic chemicals and materials are the basis of our society and our economy. Yet, in spite of all the advances in toxicology that have helped us understand and even predict toxicity associated with industrial chemicals, fundamental scientific questions crucial to the development of safer chemicals are left unanswered. Alternative strategies, such as in silico toxicity predictions, are considered the next frontier in molecular design for reduced hazard; however, such strategies are still not sufficiently developed to meet existing needs. Design strategies need to incorporate information and data at the nexus of multiple disciplines. Critically, there is a need for the incorporation of toxicology into the design phase of the molecular design process. In this Feature, we discuss the current status and future challenges in molecular design for reduced hazard.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据