Francisella tularensis IglG Belongs to a Novel Family of PAAR-Like T6SS Proteins and Harbors a Unique N-terminal Extension Required for Virulence

Type VI secretion and anti-host effectors

(2016) Abderrahman Hachani et al.   CURRENT OPINION IN MICROBIOLOGY

Aim, Load, Fire: The Type VI Secretion System, a Bacterial Nanoweapon

(2016) Francesca R. Cianfanelli et al.   TRENDS IN MICROBIOLOGY

Atomic Structure of T6SS Reveals Interlaced Array Essential to Function

(2015) Daniel L. Clemens et al.   CELL

Microinjection of Francisella tularensis and Listeria monocytogenes Reveals the Importance of Bacterial and Host Factors for Successful Replication

(2015) Lena Meyer et al.   INFECTION AND IMMUNITY

The Phyre2 web portal for protein modeling, prediction and analysis

(2015) Lawrence A Kelley et al.   Nature Protocols

HMMER web server: 2015 update

(2015) Robert D. Finn et al.   NUCLEIC ACIDS RESEARCH

Architecture and assembly of the Type VI secretion system

(2014) Abdelrahim Zoued et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

A Type VI Secretion-Related Pathway in Bacteroidetes Mediates Interbacterial Antagonism

(2014) Alistair B. Russell et al.   Cell Host & Microbe

The VgrG Proteins Are “à la Carte” Delivery Systems for Bacterial Type VI Effectors

(2014) Abderrahman Hachani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetically distinct pathways guide effector export through the type VI secretion system

(2014) John C. Whitney et al.   MOLECULAR MICROBIOLOGY

Type VI secretion system effectors: poisons with a purpose

(2014) Alistair B. Russell et al.   NATURE REVIEWS MICROBIOLOGY

CDD: NCBI's conserved domain database

(2014) Aron Marchler-Bauer et al.   NUCLEIC ACIDS RESEARCH

Importance of PdpC, IglC, IglI, and IglG for Modulation of a Host Cell Death Pathway Induced by Francisella tularensis

(2013) Marie Lindgren et al.   INFECTION AND IMMUNITY

Haemolysin Coregulated Protein Is an Exported Receptor and Chaperone of Type VI Secretion Substrates

(2013) Julie M. Silverman et al.   MOLECULAR CELL

Diverse type VI secretion phospholipases are functionally plastic antibacterial effectors

(2013) Alistair B. Russell et al.   NATURE

PAAR-repeat proteins sharpen and diversify the type VI secretion system spike

(2013) Mikhail M. Shneider et al.   NATURE

Genome characterisation of the genus Francisella reveals insight into similar evolutionary paths in pathogens of mammals and fish

(2012) Andreas Sjödin et al.   BMC GENOMICS

AIM2/ASC triggers caspase-8-dependent apoptosis in Francisella-infected caspase-1-deficient macrophages

(2012) R Pierini et al.   CELL DEATH AND DIFFERENTIATION

Competitive binding of UBPY and ubiquitin to the STAM2 SH3 domain revealed by NMR

(2012) Anja Lange et al.   FEBS LETTERS

IcmF Family Protein TssM Exhibits ATPase Activity and Energizes Type VI Secretion

(2012) Lay-Sun Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Unique Substrates Secreted by the Type VI Secretion System of Francisella tularensis during Intramacrophage Infection

(2012) Jeanette E. Bröms et al.   PLoS One

The host-binding domain of the P2 phage tail spike reveals a trimeric iron-binding structure

(2011) Eiki Yamashita et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

IglG and IglI of the Francisella Pathogenicity Island Are Important Virulence Determinants of Francisella tularensis LVS

(2011) Jeanette E. Bröms et al.   INFECTION AND IMMUNITY

The structure of the Helicobacter pylori ferric uptake regulator Fur reveals three functional metal binding sites

(2011) Cyril Dian et al.   MOLECULAR MICROBIOLOGY

MonitoringShigella flexnerivacuolar escape by flow cytometry

(2011) Katharina Nothelfer et al.   Virulence

Identification of Functional Toxin/Immunity Genes Linked to Contact-Dependent Growth Inhibition (CDI) and Rearrangement Hotspot (Rhs) Systems

(2011) Stephen J. Poole et al.   PLoS Genetics

Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis

(2010) J. W. Jones et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role of the Francisella Tularensis Pathogenicity Island in Type VI Secretion, Intracellular Survival, and Modulation of Host Cell Signaling

(2010) Jeanette E. Bröms et al.   Frontiers in Microbiology

Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources?

(2009) Frédéric Boyer et al.   BMC GENOMICS

Francisella tularensis Phagosomal Escape Does Not Require Acidification of the Phagosome

(2009) D. L. Clemens et al.   INFECTION AND IMMUNITY

A Conserved  -Helix Essential for a Type VI Secretion-Like System of Francisella tularensis

(2009) J. E. Broms et al.   JOURNAL OF BACTERIOLOGY

ACEMD: Accelerating Biomolecular Dynamics in the Microsecond Time Scale

(2009) M. J. Harvey et al.   Journal of Chemical Theory and Computation

The Francisella tularensis pathogenicity island encodes a secretion system that is required for phagosome escape and virulence

(2009) Jeffrey R. Barker et al.   MOLECULAR MICROBIOLOGY

Identification of Genes Contributing to the Virulence of Francisella tularensis SCHU S4 in a Mouse Intradermal Infection Model

(2009) Konstantin Kadzhaev et al.   PLoS One

Molecular Evolutionary Consequences of Niche Restriction in Francisella tularensis, a Facultative Intracellular Pathogen

(2009) Pär Larsson et al.   PLoS Pathogens

I-TASSER server for protein 3D structure prediction

(2008) Yang Zhang   BMC BIOINFORMATICS

Type VI secretion: a beginner's guide

(2008) Lewis EH Bingle et al.   CURRENT OPINION IN MICROBIOLOGY

MglA and Igl Proteins Contribute to the Modulation of Francisella tularensis Live Vaccine Strain-Containing Phagosomes in Murine Macrophages

(2008) L. Bonquist et al.   INFECTION AND IMMUNITY

Genetic Dissection of the Francisella novicida Restriction Barrier

(2008) L. A. Gallagher et al.   JOURNAL OF BACTERIOLOGY

How do bacterial cells ensure that metalloproteins get the correct metal?

(2008) Kevin J. Waldron et al.   NATURE REVIEWS MICROBIOLOGY

Metal Chelation and Inhibition of Bacterial Growth in Tissue Abscesses

(2008) Brian D. Corbin et al.   SCIENCE