Broadly-Reactive Neutralizing and Non-neutralizing Antibodies Directed against the H7 Influenza Virus Hemagglutinin Reveal Divergent Mechanisms of Protection

Age Dependence and Isotype Specificity of Influenza Virus Hemagglutinin Stalk-Reactive Antibodies in Humans

(2016) Raffael Nachbagauer et al.   mBio

Household transmissibility of avian influenza A (H7N9) virus, China, February to May 2013 and October 2013 to March 2014

(2015) Y Yang et al.   Eurosurveillance

Effect of Varying Doses of a Monovalent H7N9 Influenza Vaccine With and Without AS03 and MF59 Adjuvants on Immune Response

(2015) Lisa A. Jackson et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Preexisting human antibodies neutralize recently emerged H7N9 influenza strains

(2015) Carole J. Henry Dunand et al.   JOURNAL OF CLINICAL INVESTIGATION

High-Affinity H7 Head and Stalk Domain–Specific Antibody Responses to an Inactivated Influenza H7N7 Vaccine After Priming With Live Attenuated Influenza Vaccine

(2015) Jessica L. Halliley et al.   JOURNAL OF INFECTIOUS DISEASES

AS03-adjuvanted H7N1 detergent-split virion vaccine is highly immunogenic in unprimed mice and induces cross-reactive antibodies to emerged H7N9 and additional H7 subtypes

(2015) Corey P. Mallett et al.   VACCINE

Using Computational Modeling To Optimize the Design of Antibodies That Trap Viruses in Mucus

(2015) Timothy Wessler et al.   ACS Infectious Diseases

Antibodies to Antigenic Site A of Influenza H7 Hemagglutinin Provide Protection against H7N9 Challenge

(2015) Falko Schmeisser et al.   PLoS One

Transient Antibody-Mucin Interactions Produce a Dynamic Molecular Shield against Viral Invasion

(2014) Alex Chen et al.   BIOPHYSICAL JOURNAL

An H7N1 Influenza Virus Vaccine Induces Broadly Reactive Antibody Responses against H7N9 in Humans

(2014) Florian Krammer et al.   Clinical and Vaccine Immunology

Serological Responses to an Avian Influenza A/H7N9 Vaccine Mixed at the Point-of-Use With MF59 Adjuvant

(2014) Mark J. Mulligan et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Crucial Role of Aspartic Acid at Position 265 in the CH2 Domain for Murine IgG2a and IgG2b Fc-Associated Effector Functions

(2014) L. Baudino et al.   JOURNAL OF IMMUNOLOGY

Divergent H7 Immunogens Offer Protection from H7N9 Virus Challenge

(2014) F. Krammer et al.   JOURNAL OF VIROLOGY

Characterization of a Broadly Neutralizing Monoclonal Antibody That Targets the Fusion Domain of Group 2 Influenza A Virus Hemagglutinin

(2014) G. S. Tan et al.   JOURNAL OF VIROLOGY

Broadly neutralizing hemagglutinin stalk–specific antibodies require FcγR interactions for protection against influenza virus in vivo

(2014) David J DiLillo et al.   NATURE MEDICINE

Assessment of Human Immune Responses to H7 Avian Influenza Virus of Pandemic Potential: Results from a Placebo–Controlled, Randomized Double–Blind Phase I Study of Live Attenuated H7N3 Influenza Vaccine

(2014) Larisa Rudenko et al.   PLoS One

A Cell Culture-Derived MF59-Adjuvanted Pandemic A/H7N9 Vaccine Is Immunogenic in Adults

(2014) S. A. Bart et al.   Science Translational Medicine

Live attenuated H7N7 influenza vaccine primes for a vigorous antibody response to inactivated H7N7 influenza vaccine

(2014) Tara M. Babu et al.   VACCINE

H7N9 influenza viruses interact preferentially with  2,3-linked sialic acids and bind weakly to  2,6-linked sialic acids

(2013) I. Ramos et al.   JOURNAL OF GENERAL VIROLOGY

Induction of Cross-Reactive Antibodies to Novel H7N9 Influenza Virus by Recombinant Newcastle Disease Virus Expressing a North American Lineage H7 Subtype Hemagglutinin

(2013) P. H. Goff et al.   JOURNAL OF VIROLOGY

Influenza A Virus Hemagglutinin Trimerization Completes Monomer Folding and Antigenicity

(2013) J. G. Magadan et al.   JOURNAL OF VIROLOGY

Antibody-Dependent Cellular Cytotoxicity Is Associated with Control of Pandemic H1N1 Influenza Virus Infection of Macaques

(2013) S. Jegaskanda et al.   JOURNAL OF VIROLOGY

Human co-infection with novel avian influenza A H7N9 and influenza A H3N2 viruses in Jiangsu province, China

(2013) Yefei Zhu et al.   LANCET

A Recombinant Viruslike Particle Influenza A (H7N9) Vaccine

(2013) Louis F. Fries et al.   NEW ENGLAND JOURNAL OF MEDICINE

Human Infection with a Novel Avian-Origin Influenza A (H7N9) Virus

(2013) Rongbao Gao et al.   NEW ENGLAND JOURNAL OF MEDICINE

Preferential Recognition of Avian-Like Receptors in Human Influenza A H7N9 Viruses

(2013) R. Xu et al.   SCIENCE

Structures and Receptor Binding of Hemagglutinins from Human-Infecting H7N9 Influenza Viruses

(2013) Y. Shi et al.   SCIENCE

H7N3 live attenuated influenza vaccine has a potential to protect against new H7N9 avian influenza virus

(2013) Larisa Rudenko et al.   VACCINE

Development of influenza H7N9 virus like particle (VLP) vaccine: Homologous A/Anhui/1/2013 (H7N9) protection and heterologous A/chicken/Jalisco/CPA1/2012 (H7N3) cross-protection in vaccinated mice challenged with H7N9 virus

(2013) Gale E. Smith et al.   VACCINE

One-shot vaccination with an insect cell-derived low-dose influenza A H7 virus-like particle preparation protects mice against H7N9 challenge

(2013) Miriam Klausberger et al.   VACCINE

A Pan-H1 Anti-Hemagglutinin Monoclonal Antibody with Potent Broad-Spectrum Efficacy In Vivo

(2012) G. S. Tan et al.   JOURNAL OF VIROLOGY

A Carboxy-Terminal Trimerization Domain Stabilizes Conformational Epitopes on the Stalk Domain of Soluble Recombinant Hemagglutinin Substrates

(2012) Florian Krammer et al.   PLoS One

Residual Baculovirus in Insect Cell-Derived Influenza Virus-Like Particle Preparations Enhances Immunogenicity

(2012) Irina Margine et al.   PLoS One

A Randomized Clinical Trial of an Inactivated Avian Influenza A (H7N7) Vaccine

(2012) Robert B. Couch et al.   PLoS One

Trichoplusia ni cells (High FiveTM) are highly efficient for the production of influenza A virus-like particles: a comparison of two insect cell lines as production platforms for influenza vaccines

(2010) Florian Krammer et al.   MOLECULAR BIOTECHNOLOGY

A phase I clinical trial of a PER.C6® cell grown influenza H7 virus vaccine

(2009) Rebecca J. Cox et al.   VACCINE