Protein Kinase R Degradation Is Essential for Rift Valley Fever Virus Infection and Is Regulated by SKP1-CUL1-F-box (SCF)FBXW11-NSs E3 Ligase

A ΩXaV motif in the Rift Valley fever virus NSs protein is essential for degrading p62, forming nuclear filaments and virulence

(2015) Normand Cyr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Virulence Factor NSs of Rift Valley Fever Virus Recruits the F-Box Protein FBXO3 To Degrade Subunit p62 of General Transcription Factor TFIIH

(2014) M. Kainulainen et al.   JOURNAL OF VIROLOGY

Substrate Trapping Proteomics Reveals Targets of the βTrCP2/FBXW11 Ubiquitin Ligase

(2014) Tai Young Kim et al.   MOLECULAR AND CELLULAR BIOLOGY

Critical role for IL-1β in DNA damage-induced mucositis

(2014) Naama Kanarek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High Content Image-Based Screening of a Protease Inhibitor Library Reveals Compounds Broadly Active against Rift Valley Fever Virus and Other Highly Pathogenic RNA Viruses

(2014) Rajini Mudhasani et al.   PLoS Neglected Tropical Diseases

IFITM-2 and IFITM-3 but Not IFITM-1 Restrict Rift Valley Fever Virus

(2013) R. Mudhasani et al.   JOURNAL OF VIROLOGY

Reactive oxygen species activate NFκB (p65) and p53 and induce apoptosis in RVFV infected liver cells

(2013) Aarthi Narayanan et al.   VIROLOGY

Role of the cytosolic tails of Rift Valley fever virus envelope glycoproteins in viral morphogenesis

(2013) Xavier Carnec et al.   VIROLOGY

Induction of DNA Damage Signaling upon Rift Valley Fever Virus Infection Results in Cell Cycle Arrest and Increased Viral Replication

(2012) Alan Baer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Acid-Activated Structural Reorganization of the Rift Valley Fever Virus Gc Fusion Protein

(2012) S. M. de Boer et al.   JOURNAL OF VIROLOGY

Rift Valley fever virus NSs inhibits host transcription independently of the degradation of dsRNA-dependent protein kinase PKR

(2012) Birte Kalveram et al.   VIROLOGY

NSs Protein of Rift Valley Fever Virus Promotes Posttranslational Downregulation of the TFIIH Subunit p62

(2011) B. Kalveram et al.   JOURNAL OF VIROLOGY

DEPTOR, an mTOR Inhibitor, Is a Physiological Substrate of SCFβTrCP E3 Ubiquitin Ligase and Regulates Survival and Autophagy

(2011) Yongchao Zhao et al.   MOLECULAR CELL

The cytoplasmic tail of hantavirus Gn glycoprotein interacts with RNA

(2011) Tomas Strandin et al.   VIROLOGY

Specificity, location and function of βTrCP isoforms and their splice variants

(2010) Joyce Putters et al.   CELLULAR SIGNALLING

Rapid Accumulation of Virulent Rift Valley Fever Virus in Mice from an Attenuated Virus Carrying a Single Nucleotide Substitution in the M RNA

(2010) John C. Morrill et al.   PLoS One

Evaluation of the efficacy and safety of the Rift Valley Fever Clone 13 vaccine in sheep

(2010) Baptiste Dungu et al.   VACCINE

Tipping the Balance: Antagonism of PKR Kinase and ADAR1 Deaminase Functions by Virus Gene Products

(2009) Cyril X. George et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

NSs Protein of Rift Valley Fever Virus Induces the Specific Degradation of the Double-Stranded RNA-Dependent Protein Kinase

(2009) M. Habjan et al.   JOURNAL OF VIROLOGY

An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer

(2009) Teresa A. Soucy et al.   NATURE

Rift Valley Fever Virus NSs Protein Promotes Post-Transcriptional Downregulation of Protein Kinase PKR and Inhibits eIF2α Phosphorylation

(2009) Tetsuro Ikegami et al.   PLoS Pathogens

WD40 protein FBW5 promotes ubiquitination of tumor suppressor TSC2 by DDB1-CUL4-ROC1 ligase

(2008) J. Hu et al.   GENES & DEVELOPMENT