Neutrophil and Alveolar Macrophage-Mediated Innate Immune Control of Legionella pneumophila Lung Infection via TNF and ROS

Formation of a pathogen vacuole according toLegionella pneumophila: how to kill one bird with many stones

(2015) Ivo Finsel et al.   CELLULAR MICROBIOLOGY

IL-1R signaling enables bystander cells to overcome bacterial blockade of host protein synthesis

(2015) Alan M. Copenhaver et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human caspase-4 mediates noncanonical inflammasome activation against gram-negative bacterial pathogens

(2015) Cierra N. Casson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Legionnaires' Disease and Associated Comorbid Conditions as Causes of Death in the U.S., 2000–2010

(2015) Ranjana N. Wickramasekaran et al.   PUBLIC HEALTH REPORTS

Automobile windshield washer fluid: A potential source of transmission for Legionella

(2015) David Otto Schwake et al.   SCIENCE OF THE TOTAL ENVIRONMENT

The Legionella Kinase LegK2 Targets the ARP2/3 Complex To Inhibit Actin Nucleation on Phagosomes and Allow Bacterial Evasion of the Late Endocytic Pathway

(2015) Céline Michard et al.   mBio

Caspase-11 and caspase-1 differentially modulate actin polymerization via RhoA and Slingshot proteins to promote bacterial clearance

(2015) Kyle Caution et al.   Scientific Reports

Alveolar Macrophages and Neutrophils Are the Primary Reservoirs for Legionella pneumophila and Mediate Cytosolic Surveillance of Type IV Secretion

(2014) Alan M. Copenhaver et al.   INFECTION AND IMMUNITY

NAIP and Ipaf Control Legionella pneumophila Replication in Human Cells

(2014) M. Vinzing et al.   JOURNAL OF IMMUNOLOGY

A Novel Role for Neutrophils As Critical Activators of NK Cells

(2014) R. Sporri et al.   JOURNAL OF IMMUNOLOGY

Interleukin 1 Receptor–Driven Neutrophil Recruitment Accounts to MyD88–Dependent Pulmonary Clearance ofLegionella pneumophilaInfection In Vivo

(2014) Danielle P. A. Mascarenhas et al.   JOURNAL OF INFECTIOUS DISEASES

Epidemiology and clinical management of Legionnaires' disease

(2014) Nick Phin et al.   LANCET INFECTIOUS DISEASES

Molecular Basis for Specific Recognition of Bacterial Ligands by NAIP/NLRC4 Inflammasomes

(2014) Jeannette L. Tenthorey et al.   MOLECULAR CELL

VipD is a Rab5-activated phospholipase A1 that protects Legionella pneumophila from endosomal fusion

(2014) A. H. Gaspar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Neutrophil NLRC4 Inflammasome Selectively Promotes IL-1β Maturation without Pyroptosis during Acute Salmonella Challenge

(2014) Kaiwen W. Chen et al.   Cell Reports

Pneumonia por Legionella após uso de Infliximabe em paciente com Artrite Reumatoide

(2014) Karina de Souza Giassi et al.   Revista Brasileira De Reumatologia

Incidence and Risk Factors of Legionella pneumophila Pneumonia During Anti-Tumor Necrosis Factor Therapy

(2013) Fanny Lanternier et al.   CHEST

Lysosomal exocytosis and caspase-8-mediated apoptosis in UVA-irradiated keratinocytes

(2013) Hanna Appelqvist et al.   JOURNAL OF CELL SCIENCE

IL-1  Signaling Initiates the Inflammatory Response to Virulent Legionella pneumophila In Vivo

(2013) K. C. Barry et al.   JOURNAL OF IMMUNOLOGY

Molecular mimicry and original biochemical strategies for the biogenesis of a Legionella pneumophila replicative niche in phagocytic cells

(2013) Julie Allombert et al.   MICROBES AND INFECTION

Cysteine cathepsins are not critical for TRAIL- and CD95-induced apoptosis in several human cancer cell lines

(2012) Aleš Špes et al.   BIOLOGICAL CHEMISTRY

Caspase-11 Promotes the Fusion of Phagosomes Harboring Pathogenic Bacteria with Lysosomes by Modulating Actin Polymerization

(2012) Anwari Akhter et al.   IMMUNITY

Identification of Protective B Cell Antigens of Legionella pneumophila

(2012) S. S. Weber et al.   JOURNAL OF IMMUNOLOGY

The human apoptosis inhibitor NAIP induces pyroptosis in macrophages infected with Legionella pneumophila

(2012) Nanako Katagiri et al.   MICROBES AND INFECTION

Membrane-Bound TNF Induces Protective Immune Responses to M. bovis BCG Infection: Regulation of memTNF and TNF Receptors Comparing Two memTNF Molecules

(2012) Maria L. Olleros et al.   PLoS One

Dynamics of a Cytokine Storm

(2012) Hao Hong Yiu et al.   PLoS One

Caspases and immunity in a deadly grip

(2012) Ian G. Rodrigue-Gervais et al.   TRENDS IN IMMUNOLOGY

Membrane Damage during Listeria monocytogenes Infection Triggers a Caspase-7 Dependent Cytoprotective Response

(2012) Sara K. B. Cassidy et al.   PLoS Pathogens

Dissection of a type I interferon pathway in controlling bacterial intracellular infection in mice

(2011) Juliane Lippmann et al.   CELLULAR MICROBIOLOGY

Two signal models in innate immunity

(2011) Mary F. Fontana et al.   IMMUNOLOGICAL REVIEWS

Differential Requirements for NAIP5 in Activation of the NLRC4 Inflammasome

(2011) Karla L. Lightfield et al.   INFECTION AND IMMUNITY

Activation of NLRC4 by Flagellated Bacteria Triggers Caspase-1-Dependent and -Independent Responses To Restrict Legionella pneumophila Replication in Macrophages and In Vivo

(2011) M. S. F. Pereira et al.   JOURNAL OF IMMUNOLOGY

Nonhematopoietic Cells Are Key Players in Innate Control of Bacterial Airway Infection

(2011) S. LeibundGut-Landmann et al.   JOURNAL OF IMMUNOLOGY

Non-canonical inflammasome activation targets caspase-11

(2011) Nobuhiko Kayagaki et al.   NATURE

Secreted Bacterial Effectors That Inhibit Host Protein Synthesis Are Critical for Induction of the Innate Immune Response to Virulent Legionella pneumophila

(2011) Mary F. Fontana et al.   PLoS Pathogens

Immune Control of Legionella Infection: An in vivo Perspective

(2011) Ralf Schuelein et al.   Frontiers in Microbiology

Modulation of Host Cell Function byLegionella pneumophilaType IV Effectors

(2010) Andree Hubber et al.   Annual Review of Cell and Developmental Biology

Lysosomal membrane permeabilization and cathepsin release is a Bax/Bak-dependent, amplifying event of apoptosis in fibroblasts and monocytes

(2010) C Oberle et al.   CELL DEATH AND DIFFERENTIATION

Sequential changes of Legionella antigens and bacterial load in the lungs and urines of a mouse model of pneumonia

(2010) Yu Chen et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria

(2010) Edward A Miao et al.   NATURE IMMUNOLOGY

Inhibition of Host Vacuolar H+-ATPase Activity by a Legionella pneumophila Effector

(2010) Li Xu et al.   PLoS Pathogens

Lung Abscess Caused by Legionella Species: Implication of the Immune Status of Hosts

(2009) Hui Yu et al.   INTERNAL MEDICINE

Calpain activates caspase-8 in neuron-like differentiated PC12 cells via the amyloid-β-peptide and CD95 pathways

(2009) Tali Vaisid et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Caspase-7 Activation by the Nlrc4/Ipaf Inflammasome Restricts Legionella pneumophila Infection

(2009) Anwari Akhter et al.   PLoS Pathogens

Legionella pneumophilaEnhC is required for efficient replication in tumour necrosis factor α-stimulated macrophages

(2008) Mingyu Liu et al.   CELLULAR MICROBIOLOGY

Host cell processes that influence the intracellular survival of Legionella pneumophila

(2008) Sunny Shin et al.   CELLULAR MICROBIOLOGY

TNF receptor 1 and 2 contribute in different ways to resistance to Legionella pneumophila-induced mortality in mice

(2008) Masaki Fujita et al.   CYTOKINE

In vivo effect of adhesion inhibitor heparin on Legionella pneumophila pathogenesis in a murine pneumonia model

(2008) Florence Ader et al.   INTENSIVE CARE MEDICINE

Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin

(2008) Karla L Lightfield et al.   NATURE IMMUNOLOGY

The Legionella pneumophila replication vacuole: making a cosy niche inside host cells

(2008) Ralph R. Isberg et al.   NATURE REVIEWS MICROBIOLOGY

Type IV Secretion-Dependent Activation of Host MAP Kinases Induces an Increased Proinflammatory Cytokine Response to Legionella pneumophila

(2008) Sunny Shin et al.   PLoS Pathogens

Icm/Dot-dependent upregulation of phagocytosis by Legionella pneumophila

(2003) Hubert Hilbi et al.   MOLECULAR MICROBIOLOGY