Comparative Proteomics Reveals Strain-Specific β-TrCP Degradation via Rotavirus NSP1 Hijacking a Host Cullin-3-Rbx1 Complex

Targeting Viral Proteostasis Limits Influenza Virus, HIV, and Dengue Virus Infection

(2016) Nicholas S. Heaton et al.   IMMUNITY

Rotavirus NSP1 Associates with Components of the Cullin RING Ligase Family of E3 Ubiquitin Ligases

(2016) Lindy M. Lutz et al.   JOURNAL OF VIROLOGY

Hepatitis B virus X protein identifies the Smc5/6 complex as a host restriction factor

(2016) Adrien Decorsière et al.   NATURE

NSP1 of human rotaviruses commonly inhibits NF-κB signalling by inducing β-TrCP degradation

(2015) Izabel J. M. Di Fiore et al.   JOURNAL OF GENERAL VIROLOGY

Human Intestinal Enteroids: a New Model To Study Human Rotavirus Infection, Host Restriction, and Pathophysiology

(2015) Kapil Saxena et al.   JOURNAL OF VIROLOGY

A Combined Proteomics/Genomics Approach Links Hepatitis C Virus Infection with Nonsense-Mediated mRNA Decay

(2015) Holly R. Ramage et al.   MOLECULAR CELL

Global Mapping of Herpesvirus-Host Protein Complexes Reveals a Transcription Strategy for Late Genes

(2015) Zoe H. Davis et al.   MOLECULAR CELL

Identification and characterization of essential genes in the human genome

(2015) T. Wang et al.   SCIENCE

Putative E3 Ubiquitin Ligase of Human Rotavirus Inhibits NF-κB Activation by Using Molecular Mimicry To Target β-TrCP

(2015) Marco Morelli et al.   mBio

The Nuclear Oncogene SET Controls DNA Repair by KAP1 and HP1 Retention to Chromatin

(2015) Alkmini Kalousi et al.   Cell Reports

Long-Distance Interferon Signaling within the Brain Blocks Virus Spread

(2014) A. N. van den Pol et al.   JOURNAL OF VIROLOGY

Efficacy of a monovalent human-bovine (116E) rotavirus vaccine in Indian infants: a randomised, double-blind, placebo-controlled trial

(2014) Nita Bhandari et al.   LANCET

MAVS Protein Is Attenuated by Rotavirus Nonstructural Protein 1

(2014) Satabdi Nandi et al.   PLoS One

A systems-wide screen identifies substrates of the SCF TrCP ubiquitin ligase

(2014) T. Y. Low et al.   Science Signaling

Epigenetic Reprogramming of the Type III Interferon Response Potentiates Antiviral Activity and Suppresses Tumor Growth

(2014) Siyuan Ding et al.   PLOS BIOLOGY

Dynamic expression profiling of type I and type III interferon-stimulated hepatocytes reveals a stable hierarchy of gene expression

(2013) Christopher R. Bolen et al.   HEPATOLOGY

Golgi-associated RhoBTB3 targets Cyclin E for ubiquitylation and promotes cell cycle progression

(2013) Albert Lu et al.   JOURNAL OF CELL BIOLOGY

Rotavirus NSP1 Mediates Degradation of Interferon Regulatory Factors through Targeting of the Dimerization Domain

(2013) M. M. Arnold et al.   JOURNAL OF VIROLOGY

Rotavirus NSP1 Protein Inhibits Interferon-Mediated STAT1 Activation

(2013) A. Sen et al.   JOURNAL OF VIROLOGY

Adenovirus Precursor pVII Protein Stability Is Regulated By Its Propeptide Sequence

(2013) Raviteja Inturi et al.   PLoS One

Rotavirus NSP1 inhibits interferon induced non-canonical NFκB activation by interacting with TNF receptor associated factor 2

(2013) Parikshit Bagchi et al.   VIROLOGY

The Battle between Rotavirus and Its Host for Control of the Interferon Signaling Pathway

(2013) Michelle M. Arnold et al.   PLoS Pathogens

Viral immune modulators perturb the human molecular network by common and unique strategies

(2012) Andreas Pichlmair et al.   NATURE

Stem Cell-Derived Human Intestinal Organoids as an Infection Model for Rotaviruses

(2012) S. R. Finkbeiner et al.   mBio

RNAi Screening Reveals Proteasome- and Cullin3-Dependent Stages in Vaccinia Virus Infection

(2012) Jason Mercer et al.   Cell Reports

The Early Interferon Response to Rotavirus Is Regulated by PKR and Depends on MAVS/IPS-1, RIG-I, MDA-5, and IRF3

(2011) A. Sen et al.   JOURNAL OF VIROLOGY

The cullin protein family

(2011) Antonio Sarikas et al.   GENOME BIOLOGY

Roles of VP4 and NSP1 in Determining the Distinctive Replication Capacities of Simian Rotavirus RRV and Bovine Rotavirus UK in the Mouse Biliary Tract

(2010) N. Feng et al.   JOURNAL OF VIROLOGY

Rotavirus and Reovirus Modulation of the Interferon Response

(2009) Barbara Sherry   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer

(2009) Teresa A. Soucy et al.   NATURE

RBX1/ROC1 disruption results in early embryonic lethality due to proliferation failure, partially rescued by simultaneous loss of p27

(2009) M. Tan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-throughput generation of tagged stable cell lines for proteomic analysis

(2009) Jorge Z. Torres et al.   PROTEOMICS

Rotavirus Antagonism of the Innate Immune Response

(2009) Michelle Arnold et al.   Viruses-Basel

Rotavirus NSP1 Inhibits NFκB Activation by Inducing Proteasome-Dependent Degradation of β-TrCP: A Novel Mechanism of IFN Antagonism

(2009) Joel W. Graff et al.   PLoS Pathogens

SCFβ-TRCP controls oncogenic transformation and neural differentiation through REST degradation

(2008) Thomas F. Westbrook et al.   NATURE

Small-molecule inhibition of HIV-1 Vif

(2008) Robin Nathans et al.   NATURE BIOTECHNOLOGY

Defining the TRiC/CCT interactome links chaperonin function to stabilization of newly made proteins with complex topologies

(2008) Alice Y Yam et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ectromelia virus BTB/kelch proteins, EVM150 and EVM167, interact with cullin-3-based ubiquitin ligases

(2008) Brianne A. Wilton et al.   VIROLOGY