Lyn Delivers Bacteria to Lysosomes for Eradication through TLR2-Initiated Autophagy Related Phagocytosis

Molecular characterization of LC3-associated phagocytosis reveals distinct roles for Rubicon, NOX2 and autophagy proteins

(2015) Jennifer Martinez et al.   NATURE CELL BIOLOGY

Autophagy and autophagy-related proteins in the immune system

(2015) Shusaku T Shibutani et al.   NATURE IMMUNOLOGY

Cholesterol-Rich Membrane Rafts and Lyn Are Involved in Phagocytosis during Pseudomonas aeruginosa Infection

(2014) S. Kannan et al.   JOURNAL OF IMMUNOLOGY

Atg7 Enhances Host Defense against Infection via Downregulation of Superoxide but Upregulation of Nitric Oxide

(2014) Xuefeng Li et al.   JOURNAL OF IMMUNOLOGY

MicroRNA-302b augments host defense to bacteria by regulating inflammatory responses via feedback to TLR/IRAK4 circuits

(2014) Xikun Zhou et al.   Nature Communications

Lyn regulates inflammatory responses inKlebsiella pneumoniaeinfection via the p38/NF-κB pathway

(2013) Xuefeng Li et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Autophagy Regulates Phagocytosis by Modulating the Expression of Scavenger Receptors

(2013) Diana L. Bonilla et al.   IMMUNITY

Nitric oxide–mediated regulation of ferroportin-1 controls macrophage iron homeostasis and immune function in Salmonella infection

(2013) Manfred Nairz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Autophagy in Human Health and Disease

(2013)   NEW ENGLAND JOURNAL OF MEDICINE

Lyn Facilitates Glioblastoma Cell Survival under Conditions of Nutrient Deprivation by Promoting Autophagy

(2013) Wei Michael Liu et al.   PLoS One

Role of Tissue Protection in Lethal Respiratory Viral-Bacterial Coinfection

(2013) A. M. Jamieson et al.   SCIENCE

Bacterial colonization dampens influenza-mediated acute lung injury via induction of M2 alveolar macrophages

(2013) Jian Wang et al.   Nature Communications

HIF-1α Is Essential for Effective PMN Bacterial Killing, Antimicrobial Peptide Production and Apoptosis in Pseudomonas aeruginosa Keratitis

(2013) Elizabeth A. Berger et al.   PLoS Pathogens

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

Yersinia Entry into Host Cells Requires Rab5-Dependent Dephosphorylation of PI(4,5)P2 and Membrane Scission

(2012) Helen Sarantis et al.   Cell Host & Microbe

Autophagy Protein Rubicon Mediates Phagocytic NADPH Oxidase Activation in Response to Microbial Infection or TLR Stimulation

(2012) Chul-Su Yang et al.   Cell Host & Microbe

Caspase-11 Promotes the Fusion of Phagosomes Harboring Pathogenic Bacteria with Lysosomes by Modulating Actin Polymerization

(2012) Anwari Akhter et al.   IMMUNITY

Autophagy plays an essential role in the clearance of Pseudomonas aeruginosa by alveolar macrophages

(2012) K. Yuan et al.   JOURNAL OF CELL SCIENCE

CD14 Controls the LPS-Induced Endocytosis of Toll-like Receptor 4

(2011) Ivan Zanoni et al.   CELL

Nrf2-mediated induction of p62 controls Toll-like receptor-4-driven aggresome-like induced structure formation and autophagic degradation

(2011) K.-i. Fujita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immunoamphisomes in dendritic cells amplify TLR signaling and enhance exogenous antigen presentation on MHC-II

(2010) Fabien P. Blanchet et al.   Autophagy

Delivery of Cytosolic Components by Autophagic Adaptor Protein p62 Endows Autophagosomes with Unique Antimicrobial Properties

(2010) Marisa Ponpuak et al.   IMMUNITY

Deletion of PIK3C3/Vps34 in sensory neurons causes rapid neurodegeneration by disrupting the endosomal but not the autophagic pathway

(2010) X. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alveolar Epithelial Type II Cells Activate Alveolar Macrophages and Mitigate P. Aeruginosa Infection

(2009) Shibichakravarthy Kannan et al.   PLoS One

Myeloid Src kinases regulate phagocytosis and oxidative burst in pneumococcal meningitis by activating NADPH oxidase

(2008) Robert Paul et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production

(2008) Tatsuya Saitoh et al.   NATURE