Article
Environmental Sciences
Teng Wang, Baojie Li, Hong Liao, Yan Li
Summary: The study shows that the total emissions of polycyclic aromatic hydrocarbons (PAHs) in mainland China have decreased from 2013 to 2017, mainly coming from industrial, residential/commercial, and transportation sectors. The magnitude and reasons for the decline in PAH emissions vary in different regions, with particular attention needed for the limited decline in Northwest China.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Environmental Sciences
Yan Zhang, Kaicun Wang
Summary: Meteorological observations are crucial for weather forecasting and climate change studies. The accuracy of these observations depends on the representativeness of the collected data, which is determined by the scale and density of the measurement network. In this study, a high-resolution map of precipitation representativeness in mainland China is presented, based on satellite data. The results show that daily precipitation consistency is highest in eastern China and lowest on the Tibetan Plateau, while monthly consistency is highest in Northeast China Plain, the Loess Plateau, and Middle-Lower Yangtze Plain. The density of rain gauges in the current national network is not sufficient for synoptic studies in western China, but is adequate for climate change studies based on monthly data, except in the western Tibetan Plateau and deserts with no available stations. The quality of precipitation gauge observations is more important than the spatial density for climatological studies, which can inform the placement of rain gauges.
ENVIRONMENTAL RESEARCH LETTERS
(2023)
Article
Public, Environmental & Occupational Health
Shuhan Chen, Yi Wang, Yuan Zhan, Changyu Liu, Qi Wang, Jie Feng, Yufeng Li, Huilong Chen, Zhilin Zeng
Summary: This study aimed to understand the incidence of tuberculous pleurisy (TP) in mainland China between 2005 and 2018. The incidence of TP increased during this period, with a mean incidence of 2.5 per 100,000 population. Spring was identified as the peak season for TP, with Tibet, Beijing, Xinjiang, and Inner Mongolia having the highest mean annual incidence. There was a moderate positive correlation between TP incidence, medical expenses per capita, and GDP per capita.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Medicine, General & Internal
Hui Jiang, Mengyang Liu, Yingjie Zhang, Jinfeng Yin, Zhiwei Li, Chendi Zhu, Qihuan Li, Xiangyu Luo, Tingting Ji, Junjie Zhang, Yang Yang, Xiaonan Wang, Yanxia Luo, Lixin Tao, Feng Zhang, Xiangtong Liu, Weimin Li, Xiuhua Guo
Summary: The incidence of pulmonary tuberculosis in mainland China showed a downward trend from 2005 to 2016, but the western region still had high incidence rates. Innovative and more efficient prevention and control strategies are needed, particularly among the most susceptible population of farmers and herders in western China, to achieve the World Health Organization's 2035 goal.
Article
Environmental Sciences
Xia Meng, Weidong Wang, Su Shi, Shengqiang Zhu, Peng Wang, Renjie Chen, Qingyang Xiao, Tao Xue, Guannan Geng, Qiang Zhang, Haidong Kan, Hongliang Zhang
Summary: Evaluating ozone levels at high resolutions is crucial for understanding ozone distribution characteristics and assessing exposure levels. A random forest model combining various factors was developed to predict ground ozone concentrations in China, showing an overall increasing trend from 2013 to 2019 with higher pollution in certain regions.
ENVIRONMENTAL POLLUTION
(2022)
Article
Neurosciences
Chunrui Bo, Tianqi Wang, Chengbei Hou, Jinming Han, Lixia Chen, Huixue Zhang, Lihua Wang, Hongyan Li
Summary: This study assessed the temporal changes in characteristics of ischemic stroke drug clinical trials conducted in mainland China from 2005 to 2021. The results showed a gradual increase in the number of trials each year, with a significant growth in 2014. Traditional Chinese medicines, antithrombotic therapy, and cerebral protection agents were found to have made the most extensive progress in clinical trials for ischemic stroke.
CNS NEUROSCIENCE & THERAPEUTICS
(2022)
Article
Multidisciplinary Sciences
Siyu Bie, Xijian Hu, Huiguo Zhang, Kai Wang, Zhihui Dou
Summary: This study explored the spatial-temporal distribution and influencing factors of tuberculosis relative risk in mainland China, revealing that average relative humidity, precipitation, sunshine duration, and GDP per capita have positive effects on tuberculosis risk, while temperature and pressure have negative effects. Adaptation strategies based on regional and temporal characteristics are necessary for tuberculosis prevention and control in mainland China.
SCIENTIFIC REPORTS
(2021)
Article
Infectious Diseases
Xiaowei Deng, Zhiyuan Chen, Zeyao Zhao, Junbo Chen, Mei Li, Juan Yang, Hongjie Yu
Summary: By employing a generalized linear model, the seasonal and antigenic characteristics of influenza in China from 2005-2017 were studied to inform vaccine recommendations. The study found differences in the seasonal patterns and antigenic similarity of influenza in different regions of China.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2023)
Article
Health Care Sciences & Services
Qiaofeng Zhong, Yunxia Tao, Haizhu Chen, Yu Zhou, Liling Huang, Xiaohong Han, Yuankai Shi
Summary: In mainland China, significant progress has been made in anti-lung cancer drug clinical trials over the past 16 years, with the most notable advancements seen in targeted therapy and immunotherapy.
LANCET REGIONAL HEALTH-WESTERN PACIFIC
(2021)
Article
Environmental Sciences
Jie Hou, Liyuan Chen, Bingjun Han, Yujun Li, Lu Yu, Lixi Wang, Shu Tao, Wenxin Liu
Summary: This study found widespread contamination of agricultural soils in mainland China with neonicotinoid insecticides (NEOs) and their metabolite residues. Coastal regions had higher NEO concentrations than inland regions. Soils planted with vegetables, fruits, and cotton monocrops, as well as vegetable and fruit multicrops, had the highest NEO residues. The health risk of NEOs in agricultural soils in China is extremely low, but the ecological risks require urgent attention.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Environmental Sciences
Elisa Stella, Lorenzo Mari, Jacopo Gabrieli, Carlo Barbante, Enrico Bertuzzo
Summary: This study aims to identify driving variables for anthrax transmission in the Arctic, building environmental niche maps and providing a preliminary assessment tool for local communities to reduce risks. Due to the lack of georeferenced information, further investigations are needed in certain areas to improve model accuracy and provide more accurate risk mapping.
ENVIRONMENTAL RESEARCH LETTERS
(2021)
Article
Geosciences, Multidisciplinary
Tianyu Yue, Shuiqing Yin, Yun Xie, Bofu Yu, Baoyuan Liu
Summary: This study generated new R-factor and 1-in-10-year EI30 maps for mainland China using hourly and daily rainfall data, and assessed their improvement over the existing maps. The results showed significant improvement in the new maps for the western region and some improvement for the rest of China. The study also found that increasing station density can improve the accuracy of erosivity mapping, but the benefit becomes limited once a certain density is reached.
EARTH SYSTEM SCIENCE DATA
(2022)
Article
Environmental Sciences
Lianfa Li
Summary: This study developed an adaptive method and utilized an advanced algorithm to fill in a significant amount of missing AOD data in mainland China. By improving the model testing accuracy and generating ground aerosol coefficients, it provides new insights for estimating aerosol air pollutants.
Article
Environmental Sciences
Jianjun Liu
Summary: A study developed a model to estimate surface NO2 concentrations in mainland China using high-resolution meteorological and remote sensing data, which performed well and showed good accuracy. The model can benefit environmental and health-related studies by providing valuable resources.
ENVIRONMENTAL POLLUTION
(2021)
Article
Environmental Sciences
Ting Zhao, Congke Miao, Jing Wang, Pinjie Su, Kuo Chu, Yifu Luo, Qiqi Sun, Yanzhong Yao, Youtao Song, Naishun Bu
Summary: This study analyzed over 2600 terrestrial nature reserves in mainland China at the provincial level and found that natural factors and anthropogenic activities have different influences on the geographical distribution of the nature reserves. Natural factors determine the general layout of the reserves, while human activities make the distribution patchy.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Infectious Diseases
Lingshuang Ren, Li Lin, Hua Zhang, Qianli Wang, Yibing Cheng, Qin Liu, Bing Fang, Linsen Xie, Meng Wang, Juan Yang, Jinxin Guo, Tianchen Zhang, Hongkai Lian, Jiangtao Wang, Hongjie Yu
Summary: This study aimed to explore the epidemiological and clinical characteristics of pediatric patients hospitalized with RSV or influenza infection before and during the relaxation of NPIs in central China during the COVID-19 pandemic. The results showed that RSV infections increased after the relaxation of NPIs, while influenza infections decreased. Therefore, there is a need for more effective prevention strategies to prevent RSV infections in children.
INFLUENZA AND OTHER RESPIRATORY VIRUSES
(2023)
Article
Clinical Neurology
Xiling Wang, Fulong Xiao, Yiping Wang, Xiaowei Deng, Zhiyuan Chen, Xiaosong Dong, Wei Wang, Chenyang Li, Zhifei Xu, Huijuan Wu, Huan Yu, Changjun Su, Zan Wang, Xiangdong Tang, Yunhui Lv, Yun Li, Shuchen Sun, Junying Huang, Lijuan Hao, Xuan Wei, Liying Deng, Yu-Shu Huang, Jihui Zhang, Yun-Kwok Wing, Jun Zhang, Emmanuel Mignot, Fang Han, Hongjie Yu
Summary: The incidence of narcolepsy increased during the 2009 H1N1 pandemic, possibly due to the circulation of the A(H1N1) pdm09 virus. This observation should be considered for future influenza pandemic preparedness plans.
Article
Immunology
Qianhui Wu, Hongyu Wang, Jianpeng Cai, Jingwen Ai, Yang Li, Haocheng Zhang, Sen Wang, Feng Sun, Yanpeng Wu, Jiaxin Zhou, Yan Wang, Hongjie Yu, Wenhong Zhang
Summary: Omicron and its sublineages have become the predominant strains of SARS-CoV-2 worldwide, causing large-scale outbreaks due to their high transmissibility and immune escape ability. Vaccines, particularly inactivated ones, have been widely administered to control the COVID-19 burden. A cohort study conducted in Shanghai with high vaccine coverage showed that domestically developed COVID-19 vaccines offer limited protection against asymptomatic to mild-to-moderate illness progression caused by Omicron BA.2, but provide durable protection against nonsevere illness progressing to severe illness. Partial vaccination does not provide effective protection in any situation, and vaccine effects on disease progression are relatively lower in the elderly over 80 years old. These findings contribute to the evidence on vaccine performance against Omicron infection and can enhance vaccine confidence.
EMERGING MICROBES & INFECTIONS
(2023)
Article
Multidisciplinary Sciences
Jie Gu, Hongjie Yu, Dang Lin
Summary: This study compared the efficacy and safety of bivalirudin versus heparin as the anticoagulant in patients undergoing extracorporeal membrane oxygenation (ECMO). The results showed that bivalirudin treatment significantly reduced thrombotic events, major bleeding events, and in-hospital mortality compared to heparin. However, further prospective randomized controlled studies are needed to determine the superiority of bivalirudin over heparin in the ECMO population.
Correction
Multidisciplinary Sciences
Qianli Wang, Wei Wang, Amy K. Winter, Zhifei Zhan, Marco Ajelli, Filippo Trentini, Lili Wang, Fangcai Li, Juan Yang, Xingyu Xiang, Qiaohong Liao, Jiaxin Zhou, Jinxin Guo, Xuemei Yan, Nuolan Liu, C. Jessica E. Metcalf, Bryan T. Grenfell, Hongjie Yu
NATURE COMMUNICATIONS
(2023)
Article
Microbiology
Lei You, Junbo Chen, Yibing Cheng, Yu Li, Yao-Qing Chen, Tianlei Ying, Lance Turtle, Hongjie Yu
Summary: In this study, researchers identified and cloned EV-A71-neutralizing antibodies from HFMD patients using single cell RNA and B cell receptor sequencing. They found that these antibodies, including two IgG1 monoclonal antibodies and six IgM monoclonal antibodies, effectively neutralized EV-A71. The critical residues for neutralization were conserved among different EV-A71 genotypes. These findings have translational potential for the prevention and treatment of EV-A71 infections.
Article
Computer Science, Information Systems
Die Zhang, Yong Ge, Xilin Wu, Haiyan Liu, Wenbin Zhang, Shengjie Lai
Summary: Data-driven approaches integrate spatiotemporal human mobility patterns to predict infectious disease dynamics and inform the creation of mobility-informed risk indices for outbreak detection and prevalence trend prediction. The approach successfully identified high-risk areas for disease containment and improved the accuracy of predicting case increases at the county level.
ISPRS INTERNATIONAL JOURNAL OF GEO-INFORMATION
(2023)
Article
Medicine, General & Internal
Xiaoqiang Liu, Zhonghan Sun, Zhongfang Wang, Jingjing Chen, Qianhui Wu, Yan Zheng, Xiaoyun Yang, Luhui Mo, Xuemei Yan, Wei Li, Yanxiang Zou, Huiling Song, Feng Qian, Jing Lu, Hui Zhou, Yaping Wang, Zuoyun Xiang, Hongjie Yu, Jinzhong Lin, Lin Yuan, Yan Zheng
Summary: A study in China evaluated the safety, immunogenicity, and efficacy of a heterologous vaccine schedule using different COVID-19 vaccines as the fourth dose in individuals who had received three doses of inactivated vaccines. The results showed that using RQ3013 as a booster elicited superior immune responses and provided better protection against symptomatic SARS-CoV-2 infections.
Article
Construction & Building Technology
Haiyan Liu, Jianghao Wang, Jian Liu, Yong Ge, Xiaoli Wang, Chi Zhang, Eimear Cleary, Nick W. Ruktanonchai, Corrine W. Ruktanonchai, Yongcheng Yao, Amy Wesolowski, Xin Lu, Andrew J. Tatem, Xuemei Bai, Shengjie Lai
Summary: This study proposes a framework for data-driven analysis on mobility resilience, revealing the compound effects of COVID-19 and extreme weather events on mobility recovery in cities with different socioeconomic contexts. The study finds that high temperatures and abnormal precipitation levels increase the risk of reduced mobility below the pre-pandemic baseline during outbreaks. These compound impacts are more severe in cities with high population density and low GDP levels.
SUSTAINABLE CITIES AND SOCIETY
(2023)
Article
Virology
Yonghong Zhou, Chongchen Zhou, Kai Wang, Qi Qiu, Yibing Cheng, Yu Li, Peng Cui, Lu Liang, Peng Li, Xiaowei Deng, Lili Wang, Wen Zheng, Hui Gong, Fang Wang, Meng Xu, Justin Jang Hann Chu, Lance Turtle, Hongjie Yu
Summary: Hand, foot and mouth disease (HFMD) is a major public health problem among children in the Asia-Pacific region. Stool has the highest diagnostic yield for EV-A71-infected HFMD, and if stool is unavailable, rectal swabs can be collected to achieve a similar diagnostic yield. Otherwise, throat swabs may be useful in detecting positive samples.
Article
Engineering, Multidisciplinary
Shasha Han, Ting Zhang, Yan Lyu, Shengjie Lai, Peixi Dai, Jiandong Zheng, Weizhong Yang, Xiao-Hua Zhou, Luzhao Feng
Summary: Seasonal influenza activity declined globally during the COVID-19 pandemic. The study found that mask-wearing, mobility changes, and SARS-CoV-2 interference have effects on influenza activity. These findings have implications for understanding the impact of non-pharmaceutical interventions and other respiratory diseases, as well as informing health policy and tailored public health measures.
Article
Public, Environmental & Occupational Health
Kaiwei Luo, Yanpeng Wu, Yan Wang, Ziyan Liu, Lan Yi, Shanlu Zhao, Xuemei Yan, Hao Yang, Kaiyuan Sun, Marco Ajelli, Shixiong Hu, Hongjie Yu
Summary: Little is known about the epidemiology, natural history, and transmission patterns of the SARS-CoV-2 Delta variant. This report analyzed a contained outbreak in Hunan, China, and provided insights into the characteristics of the Delta variant, including key age groups, risk factors, and transmission pathways. These findings contribute to future response efforts against SARS-CoV-2.
Article
Public, Environmental & Occupational Health
Wen Zheng, Xiaowei Deng, Cheng Peng, Xuemei Yan, Nan Zheng, Zhiyuan Chen, Juan Yang, Marco Ajelli, Juanjuan Zhang, Hongjie Yu
Summary: This study quantitatively describes the spatiotemporal transmission patterns and risk factors for the 2022 Omicron BA.2 epidemic in Shanghai and identifies associations between spatial spread metrics at the subdistrict level and demographic and socioeconomic characteristics, human mobility patterns, and adopted interventions.
Article
Public, Environmental & Occupational Health
Xinhua Chen, Xufang Bai, Xinghui Chen, Nan Zheng, Juan Yang, Juanjuan Zhang, Hongjie Yu
Article
Public, Environmental & Occupational Health
Yuxia Liang, Cheng Peng, Qian You, Maria Litvinova, Marco Ajelli, Juanjuan Zhang, Hongjie Yu
Summary: This study aims to quantify the time-varying contact patterns by age in Chinese mainland in 2020 and evaluate their impact on the transmission of SARS-CoV-2. Diary-based contact surveys revealed that during the post-epidemic period, daily contacts resumed to a moderate level in most cities, suggesting a moderate risk of resurgence. Combining school closure with a reduction of contacts at the workplace could lead to a significant reduction in the attack rate.
