Translation Regulation and RNA Granule Formation after Heat Shock of Procyclic Form Trypanosoma brucei: Many Heat-Induced mRNAs Are also Increased during Differentiation to Mammalian-Infective Forms

Integrative analysis of the Trypanosoma brucei gene expression cascade predicts differential regulation of mRNA processing and unusual control of ribosomal protein expression

(2016) Enoch B. Antwi et al.   BMC GENOMICS

Regulating a Post-Transcriptional Regulator: Protein Phosphorylation, Degradation and Translational Blockage in Control of the Trypanosome Stress-Response RNA-Binding Protein ZC3H11

(2016) Igor Minia et al.   PLoS Pathogens

Quantitative Proteomics Uncovers Novel Factors Involved in Developmental Differentiation of Trypanosoma brucei

(2016) Mario Dejung et al.   PLoS Pathogens

Transcriptomes of newly-isolated Trypanosoma brucei rhodesiense reveal hundreds of mRNAs that are co-regulated with stumpy-form markers

(2015) Julius Mulindwa et al.   BMC GENOMICS

Molecular control of irreversible bistability during trypanosome developmental commitment

(2015) Maria Rosa Domingo-Sananes et al.   JOURNAL OF CELL BIOLOGY

Novel insights into RNP granules by employing the trypanosome's microtubule skeleton as a molecular sieve

(2015) Melanie Fritz et al.   NUCLEIC ACIDS RESEARCH

The within-host dynamics of African trypanosome infections

(2015) Keith R. Matthews et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Polysomes of Trypanosoma brucei: Association with Initiation Factors and RNA-Binding Proteins

(2015) Cornelia Klein et al.   PLoS One

Extensive stage-regulation of translation revealed by ribosome profiling of Trypanosoma brucei

(2014) Bryan C Jensen et al.   BMC GENOMICS

The emerging role of RNA-binding proteins in the life cycle ofTrypanosoma brucei

(2014) Nikolay G. Kolev et al.   CELLULAR MICROBIOLOGY

Networks of gene expression regulation in Trypanosoma brucei

(2014) C.E. Clayton   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Transcriptome-wide analysis of trypanosome mRNA decay reveals complex degradation kinetics and suggests a role for co-transcriptional degradation in determining mRNA levels

(2014) Abeer Fadda et al.   MOLECULAR MICROBIOLOGY

Trypanosome MKT1 and the RNA-binding protein ZC3H11: interactions and potential roles in post-transcriptional regulatory networks

(2014) Aditi Singh et al.   NUCLEIC ACIDS RESEARCH

mRNP granules

(2014) J Ross Buchan   RNA Biology

Insights into the Trypanosome-Host Interactions Revealed through Transcriptomic Analysis of Parasitized Tsetse Fly Salivary Glands

(2014) Erich Loza Telleria et al.   PLoS Neglected Tropical Diseases

SCD6 induces ribonucleoprotein granule formation in trypanosomes in a translation-independent manner, regulated by its Lsm and RGG domains

(2013) Timothy Krüger et al.   MOLECULAR BIOLOGY OF THE CELL

Genome-wide dissection of the quorum sensing signalling pathway in Trypanosoma brucei

(2013) Binny M. Mony et al.   NATURE

Differential Localization of the Two T. brucei Poly(A) Binding Proteins to the Nucleus and RNP Granules Suggests Binding to Distinct mRNA Pools

(2013) Susanne Kramer et al.   PLoS One

Independent Pathways Can Transduce the Life-Cycle Differentiation Signal in Trypanosoma brucei

(2013) Balazs Szöőr et al.   PLoS Pathogens

Post-Transcriptional Regulation of the Trypanosome Heat Shock Response by a Zinc Finger Protein

(2013) Dorothea Droll et al.   PLoS Pathogens

RNA in development: how ribonucleoprotein granules regulate the life cycles of pathogenic protozoa

(2013) Susanne Kramer   Wiley Interdisciplinary Reviews-RNA

Bloodstream form pre-adaptation to the tsetse fly in Trypanosoma brucei

(2013) Eva Rico et al.   Frontiers in Cellular and Infection Microbiology

Through the dark continent: African trypanosome development in the tsetse fly

(2013) Brice Rotureau et al.   Frontiers in Cellular and Infection Microbiology

Expression of the RNA recognition motif protein RBP10 promotes a bloodstream-form transcript pattern in Trypanosoma brucei

(2012) Martin Wurst et al.   MOLECULAR MICROBIOLOGY

Comparative SILAC Proteomic Analysis of Trypanosoma brucei Bloodstream and Procyclic Lifecycle Stages

(2012) Michael D. Urbaniak et al.   PLoS One

Developmental Progression to Infectivity in Trypanosoma brucei Triggered by an RNA-Binding Protein

(2012) N. G. Kolev et al.   SCIENCE

Genome organization is a major component of gene expression control in response to stress and during the cell division cycle in trypanosomes

(2012) S. Kelly et al.   Open Biology

DREME: motif discovery in transcription factor ChIP-seq data

(2011) Timothy L. Bailey   BIOINFORMATICS

Trans-splicing in trypanosomes: machinery and its impact on the parasite transcriptome

(2011) Shulamit Michaeli   Future Microbiology

The Cell Cycle Regulated Transcriptome of Trypanosoma brucei

(2011) Stuart K. Archer et al.   PLoS One

Identification of the meiotic life cycle stage ofTrypanosoma bruceiin the tsetse fly

(2011) Lori Peacock et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A novel phosphatase cascade regulates differentiation in Trypanosoma brucei via a glycosomal signaling pathway

(2010) B. Szoor et al.   GENES & DEVELOPMENT

Genome-wide analysis of mRNA abundance in two life-cycle stages of Trypanosoma brucei and identification of splicing and polyadenylation sites

(2010) Tim Nicolai Siegel et al.   NUCLEIC ACIDS RESEARCH

Differential expression analysis for sequence count data

(2010) Simon Anders et al.   GENOME BIOLOGY

Transcriptome analysis of differentiating trypanosomes reveals the existence of multiple post-transcriptional regulons

(2009) Rafael Queiroz et al.   BMC GENOMICS

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

Heat shock causes a decrease in polysomes and the appearance of stress granules in trypanosomes independently of eIF2  phosphorylation at Thr169

(2008) S. Kramer et al.   JOURNAL OF CELL SCIENCE