A Novel Epigenetic Silencing Pathway Involving the Highly Conserved 5’-3’ Exoribonuclease Dhp1/Rat1/Xrn2 in Schizosaccharomyces pombe

The Paf1 complex represses small-RNA-mediated epigenetic gene silencing

(2015) Katarzyna Maria Kowalik et al.   NATURE

RNA-mediated epigenetic regulation of gene expression

(2015) Daniel Holoch et al.   NATURE REVIEWS GENETICS

Epigenetic Regulation of Chromatin States inSchizosaccharomyces pombe

(2015) Robin C. Allshire et al.   Cold Spring Harbor Perspectives in Biology

The fission yeast MTREC complex targets CUTs and unspliced pre-mRNAs to the nuclear exosome

(2015) Yang Zhou et al.   Nature Communications

The Exosome Component Rrp6 Is Required for RNA Polymerase II Termination at Specific Targets of the Nrd1-Nab3 Pathway

(2015) Melanie J. Fox et al.   PLoS Genetics

Kub5-Hera, the human Rtt103 homolog, plays dual functional roles in transcription termination and DNA repair

(2014) Julio C. Morales et al.   NUCLEIC ACIDS RESEARCH

Rat1p maintains RNA polymerase II CTD phosphorylation balance

(2014) S. Jimeno-Gonzalez et al.   RNA

The multifunctional RNase XRN2

(2013) Takashi S. Miki et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

XRN 5′→3′ exoribonucleases: Structure, mechanisms and functions

(2013) Vinay K. Nagarajan et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Mtr4-like Protein Coordinates Nuclear RNA Processing for Heterochromatin Assembly and for Telomere Maintenance

(2013) Nathan N. Lee et al.   CELL

Sir2 is required for Clr4 to initiate centromeric heterochromatin assembly in fission yeast

(2013) Benjamin J Alper et al.   EMBO JOURNAL

Argonaute and Triman Generate Dicer-Independent priRNAs and Mature siRNAs to Initiate Heterochromatin Formation

(2013) Mirela Marasovic et al.   MOLECULAR CELL

Rrp47 functions in RNA surveillance and stable RNA processing when divorced from the exoribonuclease and exosome-binding domains of Rrp6

(2013) W. Garland et al.   RNA

Position-Effect Variegation, Heterochromatin Formation, and Gene Silencing in Drosophila

(2013) S. C. R. Elgin et al.   Cold Spring Harbor Perspectives in Biology

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

Transcription-associated quality control of mRNP

(2012) Manfred Schmid et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Different means, same end—heterochromatin formation by RNAi and RNAi-independent RNA processing factors in fission yeast

(2012) Francisca E Reyes-Turcu et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Co-transcriptional degradation of aberrant pre-mRNA by Xrn2

(2012) Lee Davidson et al.   EMBO JOURNAL

Chd1 chromatin remodelers maintain nucleosome organization and repress cryptic transcription

(2012) Bianca P Hennig et al.   EMBO REPORTS

DNA replication, RNAi and epigenetic inheritance

(2012) Marlyn Gonzalez et al.   Epigenetics

The splicing factor SR45 affects the RNA-directed DNA methylation pathway in Arabidopsis

(2012) Israel Ausin et al.   Epigenetics

mRNA Decapping Factors and the Exonuclease Xrn2 Function in Widespread Premature Termination of RNA Polymerase II Transcription

(2012) Kris Brannan et al.   MOLECULAR CELL

HP1Swi6 Mediates the Recognition and Destruction of Heterochromatic RNA Transcripts

(2012) Claudia Keller et al.   MOLECULAR CELL

RNAi triggered by specialized machinery silences developmental genes and retrotransposons

(2012) Soichiro Yamanaka et al.   NATURE

Rhn1, a Nuclear Protein, Is Required for Suppression of Meiotic mRNAs in Mitotically Dividing Fission Yeast

(2012) Tomoyasu Sugiyama et al.   PLoS One

Ending the message: poly(A) signals then and now

(2011) N. J. Proudfoot   GENES & DEVELOPMENT

Asf1/HIRA Facilitate Global Histone Deacetylation and Associate with HP1 to Promote Nucleosome Occupancy at Heterochromatic Loci

(2011) Kenichi Yamane et al.   MOLECULAR CELL

Unravelling the means to an end: RNA polymerase II transcription termination

(2011) Jason N. Kuehner et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structural and biochemical studies of the 5′→3′ exoribonuclease Xrn1

(2011) Jeong Ho Chang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Defects in RNA quality control factors reveal RNAi-independent nucleation of heterochromatin

(2011) Francisca E Reyes-Turcu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

RNA Elimination Machinery Targeting Meiotic mRNAs Promotes Facultative Heterochromatin Formation

(2011) M. Zofall et al.   SCIENCE

mRNP quality control goes regulatory

(2011) Oliver Mühlemann et al.   TRENDS IN GENETICS

Stc1: A Critical Link between RNAi and Chromatin Modification Required for Heterochromatin Integrity

(2010) Elizabeth H. Bayne et al.   CELL

RNAi-dependent formation of heterochromatin and its diverse functions

(2010) Shiv IS Grewal   CURRENT OPINION IN GENETICS & DEVELOPMENT

Combinatorial, site-specific requirement for heterochromatic silencing factors in the elimination of nucleosome-free regions

(2010) J. F. Garcia et al.   GENES & DEVELOPMENT

Identification of a quality-control mechanism for mRNA 5′-end capping

(2010) Xinfu Jiao et al.   NATURE

Cooperative interaction of transcription termination factors with the RNA polymerase II C-terminal domain

(2010) Bradley M Lunde et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Roles of RNAi in chromatin regulation and epigenetic inheritance

(2010) Hugh P Cam   Epigenomics

Continuous Requirement for the Clr4 Complex But Not RNAi for Centromeric Heterochromatin Assembly in Fission Yeast Harboring a Disrupted RITS Complex

(2010) Sreenath Shanker et al.   PLoS Genetics

Trans-acting antisense RNAs mediate transcriptional gene cosuppression in S. cerevisiae

(2009) J. Camblong et al.   GENES & DEVELOPMENT

An Alpha Motif at Tas3 C Terminus Mediates RITS cis Spreading and Promotes Heterochromatic Gene Silencing

(2009) Haitao Li et al.   MOLECULAR CELL

“Cotranscriptionality”: The Transcription Elongation Complex as a Nexus for Nuclear Transactions

(2009) Roberto Perales et al.   MOLECULAR CELL

On the road to reading the RNA-interference code

(2009) Haruhiko Siomi et al.   NATURE

Structure and function of the 5′→3′ exoribonuclease Rat1 and its activating partner Rai1

(2009) Song Xiang et al.   NATURE

Diverse roles of HP1 proteins in heterochromatin assembly and functions in fission yeast

(2009) T. Fischer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of protein binding sites on U3 snoRNA and pre-rRNA by UV cross-linking and high-throughput analysis of cDNAs

(2009) S. Granneman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeted 3' Processing of Antisense Transcripts Triggers Arabidopsis FLC Chromatin Silencing

(2009) F. Liu et al.   SCIENCE

RNA Interference Guides Histone Modification during the S Phase of Chromosomal Replication

(2008) Anna Kloc et al.   CURRENT BIOLOGY

Cell cycle control of centromeric repeat transcription and heterochromatin assembly

(2008) Ee Sin Chen et al.   NATURE

Roles of the Clr4 methyltransferase complex in nucleation, spreading and maintenance of heterochromatin

(2008) Ke Zhang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY