A Differentiation Transcription Factor Establishes Muscle-Specific Proteostasis in Caenorhabditis elegans

Chaperone families and interactions in metazoa

(2016) Y. Bar-Lavan et al.   Essays in Biochemistry

Heat shock proteins as potential targets for protective strategies in neurodegeneration

(2016) Harm H Kampinga et al.   LANCET NEUROLOGY

The Biology of Proteostasis in Aging and Disease

(2015) Johnathan Labbadia et al.   Annual Review of Biochemistry

Widespread Proteome Remodeling and Aggregation in Aging C. elegans

(2015) Dirk M. Walther et al.   CELL

Ultra-structural time-course study in theC. elegansmodel for Duchenne muscular dystrophy highlights a crucial role for sarcomere-anchoring structures and sarcolemma integrity in the earliest steps of the muscle degeneration process

(2015) Nicolas Brouilly et al.   HUMAN MOLECULAR GENETICS

Loss of the proteostasis factor AIRAPL causes myeloid transformation by deregulating IGF-1 signaling

(2015) Fernando G Osorio et al.   NATURE MEDICINE

JASPAR 2016: a major expansion and update of the open-access database of transcription factor binding profiles

(2015) Anthony Mathelier et al.   NUCLEIC ACIDS RESEARCH

Motoneuronal and muscle-selective removal of ALS-related misfolded proteins: Figure 1

(2015) Valeria Crippa et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Autophagy is essential for cardiac morphogenesis during vertebrate development

(2014) Eunmyong Lee et al.   Autophagy

A Quantitative Chaperone Interaction Network Reveals the Architecture of Cellular Protein Homeostasis Pathways

(2014) Mikko Taipale et al.   CELL

Molecular chaperones are nanomachines that catalytically unfold misfolded and alternatively folded proteins

(2014) Rayees U. H. Mattoo et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The Balanced Regulation of Hsc70 by DNJ-13 and UNC-23 Is Required for Muscle Functionality

(2014) Katharina Papsdorf et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hierarchical Functional Specificity of Cytosolic Heat Shock Protein 70 (Hsp70) Nucleotide Exchange Factors in Yeast

(2014) Jennifer L. Abrams et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Caenorhabditis elegans chaperonin CCT/TRiC is required for actin and tubulin biogenesis and microvillus formation in intestinal epithelial cells

(2014) Keiko Saegusa et al.   MOLECULAR BIOLOGY OF THE CELL

Spatiotemporal transcriptomics reveals the evolutionary history of the endoderm germ layer

(2014) Tamar Hashimshony et al.   NATURE

Protein aggregation can inhibit clathrin-mediated endocytosis by chaperone competition

(2014) A. Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Chaperome Subnetwork Safeguards Proteostasis in Aging and Neurodegenerative Disease

(2014) Marc Brehme et al.   Cell Reports

Modulation of the Maladaptive Stress Response to Manage Diseases of Protein Folding

(2014) Daniela Martino Roth et al.   PLOS BIOLOGY

Comparative Analysis of Human Tissue Interactomes Reveals Factors Leading to Tissue-Specific Manifestation of Hereditary Diseases

(2014) Ruth Barshir et al.   PLoS Computational Biology

Germline stem cell arrest inhibits the collapse of somatic proteostasis early inCaenorhabditis elegansadulthood

(2013) Netta Shemesh et al.   AGING CELL

FOXO4 is necessary for neural differentiation of human embryonic stem cells

(2013) David Vilchez et al.   AGING CELL

Molecular Chaperone Functions in Protein Folding and Proteostasis

(2013) Yujin E. Kim et al.   Annual Review of Biochemistry

Regulation of Organismal Proteostasis by Transcellular Chaperone Signaling

(2013) Patricija van Oosten-Hawle et al.   CELL

The Myosin Chaperone UNC-45 Is Organized in Tandem Modules to Support Myofilament Formation in C. elegans

(2013) Linn Gazda et al.   CELL

Accelerated neurodegeneration through chaperone-mediated oligomerization of tau

(2013) Laura J. Blair et al.   JOURNAL OF CLINICAL INVESTIGATION

A Neuronal GPCR is Critical for the Induction of the Heat Shock Response in the Nematode C. elegans

(2013) M. Maman et al.   JOURNAL OF NEUROSCIENCE

The chaperone Hsp90: changing partners for demanding clients

(2013) Alina Röhl et al.   TRENDS IN BIOCHEMICAL SCIENCES

Identification of a Tissue-Selective Heat Shock Response Regulatory Network

(2013) Eric Guisbert et al.   PLoS Genetics

Developmental Milestones Punctuate Gene Expression in the Caenorhabditis Embryo

(2012) Michal Levin et al.   DEVELOPMENTAL CELL

Transcription factor redundancy and tissue-specific regulation: Evidence from functional and physical network connectivity

(2012) S. G. Kuntz et al.   GENOME RESEARCH

HSPBs: Small proteins with big implications in human disease

(2012) Harm H. Kampinga et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The small heat shock proteins family: The long forgotten chaperones

(2012) C. Garrido et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Mutations affecting the cytoplasmic functions of the co-chaperone DNAJB6 cause limb-girdle muscular dystrophy

(2012) Jaakko Sarparanta et al.   NATURE GENETICS

Regional deficiencies in chaperone-mediated autophagy underlie α-synuclein aggregation and neurodegeneration

(2012) Kristen A. Malkus et al.   NEUROBIOLOGY OF DISEASE

The Atg6/Vps30/Beclin 1 ortholog BEC-1 mediates endocytic retrograde transport in addition to autophagy inC. elegans

(2011) Alexander Ruck et al.   Autophagy

FIMO: scanning for occurrences of a given motif

(2011) Charles E. Grant et al.   BIOINFORMATICS

Caenorhabditis elegans Muscle

(2011) Guy M. Benian et al.   CIRCULATION RESEARCH

The myosin-binding UCS domain but not the Hsp90-binding TPR domain of the UNC-45 chaperone is essential for function in Caenorhabditis elegans

(2011) W. Ni et al.   JOURNAL OF CELL SCIENCE

Determining the Sub-Cellular Localization of Proteins within Caenorhabditis elegans Body Wall Muscle

(2011) Barbara Meissner et al.   PLoS One

Downregulation of the Hsp90 System Causes Defects in Muscle Cells of Caenorhabditis Elegans

(2011) Andreas M. Gaiser et al.   PLoS One

Neuronal circuitry regulates the response of Caenorhabditis elegans to misfolded proteins

(2011) V. Prahlad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HSP90 at the hub of protein homeostasis: emerging mechanistic insights

(2010) Mikko Taipale et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The HSP70 chaperone machinery: J proteins as drivers of functional specificity

(2010) Harm H. Kampinga et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The p.G154S mutation of the alpha-B crystallin gene (CRYAB) causes late-onset distal myopathy

(2010) Peter Reilich et al.   NEUROMUSCULAR DISORDERS

A Widespread Distribution of Genomic CeMyoD Binding Sites Revealed and Cross Validated by ChIP-Chip and ChIP-Seq Techniques

(2010) Haiyan Lei et al.   PLoS One

Integrative Analysis of the Caenorhabditis elegans Genome by the modENCODE Project

(2010) M. B. Gerstein et al.   SCIENCE

Genome-Wide Identification of Binding Sites Defines Distinct Functions for Caenorhabditis elegans PHA-4/FOXA in Development and Environmental Response

(2010) Mei Zhong et al.   PLoS Genetics

Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging

(2009) A. Ben-Zvi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Destabilizing Protein Polymorphisms in the Genetic Background Direct Phenotypic Expression of Mutant SOD1 Toxicity

(2009) Tali Gidalevitz et al.   PLoS Genetics

BioVenn – a web application for the comparison and visualization of biological lists using area-proportional Venn diagrams

(2008) Tim Hulsen et al.   BMC GENOMICS

Build it up-Tear it down: protein quality control in the cardiac sarcomere

(2008) M. S. Willis et al.   CARDIOVASCULAR RESEARCH

Protein quality control gets muscle into shape

(2008) Johnny Kim et al.   TRENDS IN CELL BIOLOGY