The BBSome Controls Energy Homeostasis by Mediating the Transport of the Leptin Receptor to the Plasma Membrane

20 years of leptin: From the discovery of the leptin gene to leptin in our therapeutic armamentarium

(2015) Jeffrey M. Friedman et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Regulation of Insulin Receptor Trafficking by Bardet Biedl Syndrome Proteins

(2015) Rachel D. Starks et al.   PLoS Genetics

Recurrent CNVs and SNVs at the NPHP1 Locus Contribute Pathogenic Alleles to Bardet-Biedl Syndrome

(2014) Anna Lindstrand et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Hypomorphism for RPGRIP1L, a Ciliary Gene Vicinal to the FTO Locus, Causes Increased Adiposity in Mice

(2014) George Stratigopoulos et al.   Cell Metabolism

BBS4 directly affects proliferation and differentiation of adipocytes

(2014) Olga Aksanov et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Leptin-promoted cilia assembly is critical for normal energy balance

(2014) Yu Mi Han et al.   JOURNAL OF CLINICAL INVESTIGATION

Cognitive, sensory, and psychosocial characteristics in patients with Bardet-Biedl syndrome

(2013) Danielle D. Brinckman et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Assembling a primary cilium

(2013) Sehyun Kim et al.   CURRENT OPINION IN CELL BIOLOGY

Leptin resistance is a secondary consequence of the obesity in ciliopathy mutant mice

(2013) N. F. Berbari et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Trehalose-enhanced isolation of neuronal sub-types from adult mouse brain

(2012) Alka Saxena et al.   BIOTECHNIQUES

BBS-Induced Ciliary Defect Enhances Adipogenesis, Causing Paradoxical Higher-Insulin Sensitivity, Glucose Usage, and Decreased Inflammatory Response

(2012) Vincent Marion et al.   Cell Metabolism

Intrinsic Protein-Protein Interaction-mediated and Chaperonin-assisted Sequential Assembly of Stable Bardet-Biedl Syndrome Protein Complex, the BBSome

(2012) Qihong Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Abnormal development of NG2+PDGFR-α+ neural progenitor cells leads to neonatal hydrocephalus in a ciliopathy mouse model

(2012) Calvin S Carter et al.   NATURE MEDICINE

Ablation of the Leptin Receptor in the Hypothalamic Arcuate Nucleus Abrogates Leptin-Induced Sympathetic Activation

(2011) Shannon M. Harlan et al.   CIRCULATION RESEARCH

Neuronal Receptor Activity-Modifying Protein 1 Promotes Energy Expenditure in Mice

(2011) Z. Zhang et al.   DIABETES

Patients with Bardet-Biedl Syndrome Have Hyperleptinemia Suggestive of Leptin Resistance

(2011) Penelope P. Feuillan et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The Conserved Bardet-Biedl Syndrome Proteins Assemble a Coat that Traffics Membrane Proteins to Cilia

(2010) Hua Jin et al.   CELL

Identification and Characterization of a Promoter Cassette Conferring Adipocyte-Specific Gene Expression

(2010) Zhao V. Wang et al.   ENDOCRINOLOGY

BBS6, BBS10, and BBS12 form a complex with CCT/TRiC family chaperonins and mediate BBSome assembly

(2010) S. Seo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Requirement of Bardet-Biedl syndrome proteins for leptin receptor signaling

(2009) Seongjin Seo et al.   HUMAN MOLECULAR GENETICS

Human genetics illuminates the paths to metabolic disease

(2009) Stephen O’Rahilly   NATURE

Transient ciliogenesis involving Bardet-Biedl syndrome proteins is a fundamental characteristic of adipogenic differentiation

(2009) Vincent Marion et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A BBSome Subunit Links Ciliogenesis, Microtubule Stability, and Acetylation

(2008) Alexander V. Loktev et al.   DEVELOPMENTAL CELL

Leptin resistance contributes to obesity and hypertension in mouse models of Bardet-Biedl syndrome

(2008) Kamal Rahmouni et al.   JOURNAL OF CLINICAL INVESTIGATION