UPF2-Dependent Nonsense-Mediated mRNA Decay Pathway Is Essential for Spermatogenesis by Selectively Eliminating Longer 3'UTR Transcripts

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3′UTRs take a long shot in the brain

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Expression Profiling Reveals Developmentally Regulated lncRNA Repertoire in the Mouse Male Germline1

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Ubiquitously transcribed genes use alternative polyadenylation to achieve tissue-specific expression

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(2013) Jianqiang Bao et al.   GENESIS

Global analyses of UPF1 binding and function reveal expanded scope of nonsense-mediated mRNA decay

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Translation-dependent displacement of UPF1 from coding sequences causes its enrichment in 3′ UTRs

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DHX34 and NBAS form part of an autoregulatory NMD circuit that regulates endogenous RNA targets in human cells, zebrafish and Caenorhabditis elegans

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Rules that govern UPF1 binding to mRNA 3′ UTRs

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Identification of Potential Regulatory Elements in the 5' and 3' UTRs of 12 Translationally Regulated mRNAs in Mammalian Spermatids by Comparative Genomics

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Control of Messenger RNA Fate by RNA-Binding Proteins: An Emphasis on Mammalian Spermatogenesis

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MicroRNA-449 and MicroRNA-34b/c Function Redundantly in Murine Testes by Targeting E2F Transcription Factor-Retinoblastoma Protein (E2F-pRb) Pathway

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NMD: a multifaceted response to premature translational termination

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Identification of hundreds of novel UPF1 target transcripts by direct determination of whole transcriptome stability

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Regulation of nonsense-mediated mRNA decay

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Mammalian tissues defective in nonsense-mediated mRNA decay display highly aberrant splicing patterns

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SOHLH1 and SOHLH2 coordinate spermatogonial differentiation

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STK31(TDRD8) is dynamically regulated throughout mouse spermatogenesis and interacts with MIWI protein

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The RNA-binding protein ELAVL1/HuR is essential for mouse spermatogenesis, acting both at meiotic and postmeiotic stages

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RNA Homeostasis Governed by Cell Type-Specific and Branched Feedback Loops Acting on NMD

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Male germ cells express abundant endogenous siRNAs

(2011) Rui Song et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Upf1 Senses 3′UTR Length to Potentiate mRNA Decay

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Comprehensive Polyadenylation Site Maps in Yeast and Human Reveal Pervasive Alternative Polyadenylation

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Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

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Tissue-specific mechanisms of alternative polyadenylation: testis, brain, and beyond

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Widespread Shortening of 3′UTRs by Alternative Cleavage and Polyadenylation Activates Oncogenes in Cancer Cells

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Reprogramming of 3′ Untranslated Regions of mRNAs by Alternative Polyadenylation in Generation of Pluripotent Stem Cells from Different Cell Types

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Progressive lengthening of 3' untranslated regions of mRNAs by alternative polyadenylation during mouse embryonic development

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Characterization of Two Cytoplasmic Poly(A)-Binding Proteins, PABPC1 and PABPC2, in Mouse Spermatogenic Cells1

(2008) Masanori Kimura et al.   BIOLOGY OF REPRODUCTION

NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements

(2008) J. Weischenfeldt et al.   GENES & DEVELOPMENT

Generation ofCyp17iCre transgenic mice and their application to conditionally delete estrogen receptor alpha (Esr1) from the ovary and testis

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Cre recombinase activity specific to postnatal, premeiotic male germ cells in transgenic mice

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HITS-CLIP yields genome-wide insights into brain alternative RNA processing

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Proliferating Cells Express mRNAs with Shortened 3' Untranslated Regions and Fewer MicroRNA Target Sites

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