Chronological Lifespan in Yeast Is Dependent on the Accumulation of Storage Carbohydrates Mediated by Yak1, Mck1 and Rim15 Kinases

Growth and aging: a common molecular mechanism

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TORC1 controls G1–S cell cycle transition in yeast via Mpk1 and the greatwall kinase pathway

(2015) Marta Moreno-Torres et al.   Nature Communications

The Yeast GSK-3 Homologue Mck1 Is a Key Controller of Quiescence Entry and Chronological Lifespan

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Tor-Sch9 deficiency activates catabolism of the ketone body-like acetic acid to promote trehalose accumulation and longevity

(2014) Jia Hu et al.   AGING CELL

Large-scale functional analysis of the roles of phosphorylation in yeast metabolic pathways

(2014) J. C. Schulz et al.   Science Signaling

Epigenetic Silencing Mediates Mitochondria Stress-Induced Longevity

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Rim15-dependent activation of Hsf1 and Msn2/4 transcription factors by direct phosphorylation inSaccharomyces cerevisiae

(2013) Peter Lee et al.   FEBS LETTERS

Cellular redox homeostasis, reactive oxygen species and replicative ageing inSaccharomyces cerevisiae

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mTOR is a key modulator of ageing and age-related disease

(2013) Simon C. Johnson et al.   NATURE

Somatotropic Signaling: Trade-Offs Between Growth, Reproductive Development, and Longevity

(2013) Andrzej Bartke et al.   PHYSIOLOGICAL REVIEWS

TORC1 Inhibits GSK3-Mediated Elo2 Phosphorylation to Regulate Very Long Chain Fatty Acid Synthesis and Autophagy

(2013) Christine Zimmermann et al.   Cell Reports

Synergistic effects of TOR and proteasome pathways on the yeast transcriptome and cell growth

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CDK-Dependent Hsp70 Phosphorylation Controls G1 Cyclin Abundance and Cell-Cycle Progression

(2012) Andrew W. Truman et al.   CELL

Emerging role of DYRK family protein kinases as regulators of protein stability in cell cycle control

(2012) Walter Becker   CELL CYCLE

pH neutralization protects against reduction in replicative lifespan following chronological aging in yeast

(2012) Christopher Murakami et al.   CELL CYCLE

Mitochondrial Respiratory Thresholds Regulate Yeast Chronological Life Span and its Extension by Caloric Restriction

(2012) Alejandro Ocampo et al.   Cell Metabolism

TOR and RAS pathways regulate desiccation tolerance in Saccharomyces cerevisiae

(2012) Aaron Z. Welch et al.   MOLECULAR BIOLOGY OF THE CELL

TOR Signaling Regulates Ribosome and tRNA Synthesis via LAMMER/Clk and GSK-3 Family Kinases

(2012) Jaehoon Lee et al.   MOLECULAR CELL

Yeast Endosulfines Control Entry into Quiescence and Chronological Life Span by Inhibiting Protein Phosphatase 2A

(2012) Séverine Bontron et al.   Cell Reports

The Yeast Forkhead Transcription Factors Fkh1 and Fkh2 Regulate Lifespan and Stress Response Together with the Anaphase-Promoting Complex

(2012) Spike D. L. Postnikoff et al.   PLoS Genetics

Caloric Restriction Extends Yeast Chronological Lifespan by Altering a Pattern of Age-Related Changes in Trehalose Concentration

(2012) Pavlo Kyryakov et al.   Frontiers in Physiology

A genomic analysis of chronological longevity factors in budding yeast

(2011) Christopher R. Burtner et al.   CELL CYCLE

Regulation of Yeast Chronological Life Span by TORC1 via Adaptive Mitochondrial ROS Signaling

(2011) Yong Pan et al.   Cell Metabolism

The AMPK/SNF1/SnRK1 fuel gauge and energy regulator: structure, function and regulation

(2011) Ruben Ghillebert et al.   FEBS Journal

Quick and reliable assessment of chronological life span in yeast cell populations by flow cytometry

(2011) Alejandro Ocampo et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Composition and Acidification of the Culture Medium Influences Chronological Aging Similarly in Vineyard and Laboratory Yeast

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Common toxicities of mammalian target of rapamycin inhibitors

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Initiation of the TORC1-Regulated G0 Program Requires Igo1/2, which License Specific mRNAs to Evade Degradation via the 5′-3′ mRNA Decay Pathway

(2010) Nicolas Talarek et al.   MOLECULAR CELL

Extending Healthy Life Span--From Yeast to Humans

(2010) L. Fontana et al.   SCIENCE

Phosphoproteomic Analysis Reveals Interconnected System-Wide Responses to Perturbations of Kinases and Phosphatases in Yeast

(2010) B. Bodenmiller et al.   Science Signaling

Effect of calorie restriction on the metabolic history of chronologically aging yeast

(2009) Alexander A. Goldberg et al.   EXPERIMENTAL GERONTOLOGY

Gis1 is required for transcriptional reprogramming of carbon metabolism and the stress response during transition into stationary phase in yeast

(2009) N. Zhang et al.   MICROBIOLOGY-SGM

Oxidative stress and chronological aging in glycogen-phosphorylase-deleted yeast

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Yeast Barcoders: a chemogenomic application of a universal donor-strain collection carrying bar-code identifiers

(2008) Zhun Yan et al.   NATURE METHODS

Life Span Extension by Calorie Restriction Depends on Rim15 and Transcription Factors Downstream of Ras/PKA, Tor, and Sch9

(2008) Min Wei et al.   PLoS Genetics