Gata6-Dependent GLI3 Repressor Function is Essential in Anterior Limb Progenitor Cells for Proper Limb Development

Sall4-Gli3system in early limb progenitors is essential for the development of limb skeletal elements

(2015) Ryutaro Akiyama et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BMP-mediated induction of GATA4/5/6 blocks somitic responsiveness to SHH

(2014) G. Daoud et al.   DEVELOPMENT

HAND2 Targets Define a Network of Transcriptional Regulators that Compartmentalize the Early Limb Bud Mesenchyme

(2014) Marco Osterwalder et al.   DEVELOPMENTAL CELL

Formation of Proximal and Anterior Limb Skeleton Requires Early Function of Irx3 and Irx5 and Is Negatively Regulated by Shh Signaling

(2014) Danyi Li et al.   DEVELOPMENTAL CELL

Context-dependent signal integration by the GLI code: The oncogenic load, pathways, modifiers and implications for cancer therapy

(2014) Fritz Aberger et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

GATA6 Is a Crucial Regulator of Shh in the Limb Bud

(2014) Elena Kozhemyakina et al.   PLoS Genetics

The mechanisms of Hedgehog signalling and its roles in development and disease

(2013) James Briscoe et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Combinatorial regulation of tissue specification by GATA and FOG factors

(2012) T. M. Chlon et al.   DEVELOPMENT

GLI3 Constrains Digit Number by Controlling Both Progenitor Proliferation and BMP-Dependent Exit to Chondrogenesis

(2012) Javier Lopez-Rios et al.   DEVELOPMENTAL CELL

Preaxial polydactyly caused by Gli3 haploinsufficiency is rescued by Zic3 loss of function in mice

(2012) Malgorzata E. Quinn et al.   HUMAN MOLECULAR GENETICS

Gli Proteins in Development and Disease

(2011) Chi-chung Hui et al.   Annual Review of Cell and Developmental Biology

GATA6 Activates Wnt Signaling in Pancreatic Cancer by Negatively Regulating the Wnt Antagonist Dickkopf-1

(2011) Yi Zhong et al.   PLoS One

Preaxial polydactyly: interactions among ETV, TWIST1 and HAND2 control anterior-posterior patterning of the limb

(2010) Z. Zhang et al.   DEVELOPMENT

Regulation of BMP-dependent chondrogenesis in early limb mesenchyme by TGF  signals

(2010) K. Karamboulas et al.   JOURNAL OF CELL SCIENCE

Kinetics of Hedgehog-Dependent Full-Length Gli3 Accumulation in Primary Cilia and Subsequent Degradation

(2010) X. Wen et al.   MOLECULAR AND CELLULAR BIOLOGY

Distinct Roles of Hand2 in Initiating Polarity and Posterior Shh Expression during the Onset of Mouse Limb Bud Development

(2010) Antonella Galli et al.   PLoS Genetics

A SHH-independent regulation of Gli3 is a significant determinant of anteroposterior patterning of the limb bud

(2009) Patrick Hill et al.   DEVELOPMENTAL BIOLOGY

FGF-Regulated Etv Genes Are Essential for Repressing Shh Expression in Mouse Limb Buds

(2009) Zhen Zhang et al.   DEVELOPMENTAL CELL

Fgf-Dependent Etv4/5 Activity Is Required for Posterior Restriction of Sonic hedgehog and Promoting Outgrowth of the Vertebrate Limb

(2009) Junhao Mao et al.   DEVELOPMENTAL CELL

Tulp3 is a critical repressor of mouse hedgehog signaling

(2009) Don A. Cameron et al.   DEVELOPMENTAL DYNAMICS

Tubby-like protein 3 (TULP3) regulates patterning in the mouse embryo through inhibition of Hedgehog signaling

(2009) Ryan X. Norman et al.   HUMAN MOLECULAR GENETICS

Mouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: identification of Tulp3 as a novel negative regulator of the Sonic hedgehog pathway

(2009) Victoria L. Patterson et al.   HUMAN MOLECULAR GENETICS

Vertebrate limb bud development: moving towards integrative analysis of organogenesis

(2009) Rolf Zeller et al.   NATURE REVIEWS GENETICS

A role for GATA-6 in vertebrate chondrogenesis

(2008) Alexander Alexandrovich et al.   DEVELOPMENTAL BIOLOGY

Loss of both GATA4 and GATA6 blocks cardiac myocyte differentiation and results in acardia in mice

(2008) Roong Zhao et al.   DEVELOPMENTAL BIOLOGY

Uncoupling Sonic Hedgehog Control of Pattern and Expansion of the Developing Limb Bud

(2008) Jianjian Zhu et al.   DEVELOPMENTAL CELL

Integration of growth and specification in chick wing digit-patterning

(2008) Matthew Towers et al.   NATURE